Impact of clinical trial design and execution-related factors on incidence of thromboembolic events in cancer patients: a systematic review and meta-analysis

2008 ◽  
Vol 24 (2) ◽  
pp. 497-505 ◽  
Author(s):  
Matthew W. Reynolds ◽  
Atsuko Shibata ◽  
Sean Zhao ◽  
Natalie Jones ◽  
Kyle Fahrbach ◽  
...  
2021 ◽  
Vol 12 ◽  
Author(s):  
Armin Fereidouni ◽  
Maryam Rassouli ◽  
Mahmood Salesi ◽  
Hadis Ashrafizadeh ◽  
Amir Vahedian-Azimi ◽  
...  

Background: Identifying the preferred place of death is a key indicator of the quality of death in cancer patients and one of the most important issues for health service policymakers. This study was done to determine the preferred place of death and the factors affecting it for adult patients with cancer.Methods: In this systematic review and meta-analysis study four online databases (PubMed, Scopus, web of science, ProQuest) were searched by relevant keywords. Quality assessment of papers was conducted using Newcastle-Ottawa (NOS) criterion. Odds ratios, relative risks, and 95% confidence intervals were determined for each of the factors extracted from the investigations.Results: A total of 14,920 participants of 27 studies were included into the meta-analysis. Based on the results, 55% of cancer patients with a confidence interval [95% CI (41–49)] preferred home, 17% of patients with a confidence interval [95% CI (−12%) 23)] preferred hospital and 10% of patients with confidence interval [95% CI (13–18)] preferred hospices as their favored place to die. Effective factors were also reported in the form of demographic characteristics, disease-related factors and psychosocial factors.Conclusions: This study showed that more than half of cancer patients chose home as their preferred place of death. Therefore, guided policies need to ensure that the death of the patients in the preferred place should be considered with priority.Systematic Review Registration:https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42020218680, identifier: CRD42020218680.


Geriatrics ◽  
2018 ◽  
Vol 3 (3) ◽  
pp. 34 ◽  
Author(s):  
Shóna Whelehan ◽  
Orlaith Lynch ◽  
Niall Treacy ◽  
Ciara Gleeson ◽  
Andrea Oates ◽  
...  

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