scholarly journals Oral versus intravenous proton pump inhibitors in preventing re-bleeding for patients with peptic ulcer bleeding after successful endoscopic therapy

2012 ◽  
Vol 12 (1) ◽  
Author(s):  
Hsu-Heng Yen ◽  
Chia-Wei Yang ◽  
Wei-Wen Su ◽  
Maw-Soan Soon ◽  
Shun-Sheng Wu ◽  
...  
Keyword(s):  
Peptic Ulcer ◽  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Endoscopic Therapy ◽  
Ulcer Bleeding ◽  
Peptic Ulcer Bleeding

UPDATE ON ENDOSCOPIC MANAGEMENT OF PEPTIC ULCER BLEEDING

2012 ◽  
pp. 5-11
Author(s):  
Ngoc Quy Hue Dang ◽  
Van Huy Tran
Keyword(s):  
Peptic Ulcer ◽  
High Risk ◽  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Endoscopic Therapy ◽  
Active Bleeding ◽  
Ulcer Bleeding ◽  
Endoscopic Management ◽  
High Dose ◽  
Peptic Ulcer Bleeding

Peptic ulcer bleeding is a common medical emergency and still a potentially fatal condition. It is the best managed using a multidisciplinary approach by a team with medical, endoscopic and surgical expertise. Appropriate resuscitation followed by early endoscopy for diagnosis and treatment are of major importance in these patients. Endoscopy is recommended within 24 h of presentation. Endoscopic therapy is indicated for patients with high-risk stigmata, in particular those with active bleeding and visible vessels. A combination of proton pump inhibitors and endoscopic therapy (using a combination of injection and mechanical hemostasis) offers the best chance of hemostasis for those with active bleeding ulcers. The application of an ulcer-covering hemospray is a new promising tool. High dose proton pump inhibitors should be administered intravenously for 72 h in high-risk patients. Helicobacter pylori should be tested for in all patients with peptic ulcer bleeding and eradicated if positive

EFFICACY OF ENDOSCOPIC HEMOCLIPS AND INTERMITTENT INTRAVENOUS PPI IN PEPTIC ULCER BLEEDING

2019 ◽  
pp. 40-44
Author(s):  
Van Huy Tran ◽  
Duy Lieu Dinh
Keyword(s):  
Peptic Ulcer ◽  
Key Words ◽  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Ulcer Bleeding ◽  
Peptic Ulcer Bleeding ◽  
Forrest Classification

Background: Efficacy of continuous intravenous proton- pump inhibitors (IV PPI) and hemoclips alone was proved, but data about combination of an application of endoscopy clips and intermittent IV PPI in Vietnam was still limited. This study aimed to assess the efficacy of endoscopy hemoclip combined with intermittent IV PPI in the patients of peptic ulcer bleeding. Patients and methods: 34 patients diagnosed as peptic ulcer bleeding, having Forrest classification of Ia, Ib, IIa and IIb, were enrolled. Esomeprazole was administered as 80 mg IV bolus followed by intermittent IV injection of 40 mg/8h during 72h. Results: Immediate hemostasis was achieved in all 34 patients. Only 1 patient (2.9%) had early rebleeding. No severe complications was found in this study. Conclusion: Combination of endoscopy hemoclips and intermittent PPI showed effective, safe in patients of peptic ulcer bleeding. Key words: Peptic ulcer bleeding, intermittent PPI, endoscopy hemoclip

Outcomes of Peptic Ulcer Bleeding After Treatment With Intravenous Proton Pump Inhibitors in Routine Clinical Practice

2011 ◽  
Vol 140 (5) ◽  
pp. S-740
Author(s):  
Angel Lanas ◽  
Mónica Polo-Tomás ◽  
Luis A. Garcia Rodriguez ◽  
S. García ◽  
María Teresa Arroyo ◽  
...  
Keyword(s):  
Peptic Ulcer ◽  
Clinical Practice ◽  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Routine Clinical Practice ◽  
Ulcer Bleeding ◽  
Peptic Ulcer Bleeding

Effect of proton pump inhibitors on the outcomes of peptic ulcer bleeding: comparison of event rates in routine clinical practice and a clinical trial

2013 ◽  
Vol 48 (3) ◽  
pp. 285-294 ◽  
Author(s):  
Angel Lanas ◽  
Mónica Polo-Tomas ◽  
Luis A. García-Rodríguez ◽  
Santiago García ◽  
María Teresa Arroyo-Villarino ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Peptic Ulcer ◽  
Clinical Practice ◽  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Routine Clinical Practice ◽  
Ulcer Bleeding ◽  
Peptic Ulcer Bleeding ◽  
Event Rates
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