scholarly journals Positive association of the hepatic lipase gene polymorphism c.514C > T with estrogen replacement therapy response

2011 ◽  
Vol 10 (1) ◽  
Author(s):  
Alvaro Pulchinelli ◽  
Ana Maria Massad Costa ◽  
Cristina V de Carvalho ◽  
Naiara Correa Nogueira de Souza ◽  
Mauro A Haidar ◽  
...  
Keyword(s):  
Gene Polymorphism ◽  
Replacement Therapy ◽  
Estrogen Replacement Therapy ◽  
Hepatic Lipase ◽  
Therapy Response ◽  
Positive Association ◽  
Estrogen Replacement ◽  
Lipase Gene ◽  
Hepatic Lipase Gene

Hepatic lipase gene polymorphism, pre-pregnancy overweight status and risk of preeclampsia among Peruvian women

2005 ◽  
Vol 21 (4) ◽  
pp. 211-217 ◽  
Author(s):  
Daniel A. Enquobahrie ◽  
Sixto E. Sanchez ◽  
Martin Muy-Rivera ◽  
Chunfang Qiu ◽  
Cuilin Zhang ◽  
...  
Keyword(s):  
Gene Polymorphism ◽  
Hepatic Lipase ◽  
Lipase Gene ◽  
Overweight Status ◽  
Hepatic Lipase Gene ◽  
Risk Of Preeclampsia

380-S: Hepatic Lipase Gene Polymorphism, Prepregnancy Overweight Status and Risk of Preeclampsia Among Peruvian Women

2005 ◽  
Vol 161 (Supplement_1) ◽  
pp. S95-S95
Author(s):  
D A Enquobahrie ◽  
S E Sanchez ◽  
M Muy-Rivera ◽  
C Qiu ◽  
C Zhang ◽  
...  
Keyword(s):  
Gene Polymorphism ◽  
Hepatic Lipase ◽  
Lipase Gene ◽  
Overweight Status ◽  
Hepatic Lipase Gene ◽  
Risk Of Preeclampsia

The Effects of Transdermal Estradiol and Oral Conjugated Estrogens on Haemostasis Variables

1994 ◽  
Vol 71 (04) ◽  
pp. 420-423 ◽  
Author(s):  
Ulla-Beth Kroon ◽  
G Silfverstolpe ◽  
L Tengborn
Keyword(s):  
Replacement Therapy ◽  
Estrogen Replacement Therapy ◽  
Hormone Replacement ◽  
Plasminogen Activator Inhibitor ◽  
Estrogen Replacement ◽  
Transdermal Administration ◽  
Conjugated Estrogens ◽  
Transdermal Estradiol ◽  
Estrogen Administration ◽  
Activator Inhibitor

SummaryThe effects of oral and transdermal administration of estrogen replacement therapy (ERT) have been fairly well investigated regarding lipoprotein and carbohydrate metabolism, while the effects of different modes of estrogen administration on the haemostatic system have been less well studied.To delineate and compare the effects of perorally administered conjugated estrogens (CE) and transdermally administered estradiol (E2) in doses needed for hormone replacement therapy (HRT) on haemostasis parameters, 23 postmenopausal women were engaged in a study with an open cross-over design. The doses compared (0.625 mg CE and 50 μg E2/24h) are the lowest which, with few exceptions, eliminate climacteric symptoms. Both CE and E2 increased factor VII:C, factor VII:Ag, and the prothrombin fragment1+2. The increase in factor VII:Ag, however, was significantly higher after treatment with CE. These changes were all towards a state of hypercoagulability. Furthermore, CE decreased plasminogen activator inhibitor (PAI) and the thrombin-antithrombin complexes (TAT), as well as antithrombin (ATIII).

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