scholarly journals Characteristics of High-density Lipoprotein Subclasses Distribution for Subjects with Desirable Total Cholesterol Levels

2011 ◽  
Vol 10 (1) ◽  
pp. 64 ◽  
Author(s):  
Li Tian ◽  
Shiyin Long ◽  
Mingde Fu ◽  
Yinghui Liu ◽  
Yanhua Xu ◽  
...  
Keyword(s):  
High Density Lipoprotein ◽  
Total Cholesterol ◽  
Density Lipoprotein ◽  
High Density ◽  
Lipoprotein Subclasses ◽  
Cholesterol Levels

A Retrospective Evaluation of the Inflammatory Marker C-Reactive Protein (CRP), Cholesterol and High-Density Lipoproteins in Patients with Major Depression: Preliminary Findings

2005 ◽  
Vol 3 (3) ◽  
pp. 127-134 ◽  
Author(s):  
F. Gambi ◽  
D. De Berardis ◽  
D. Campanella ◽  
A. Carano ◽  
G. Sepede ◽  
...  
Keyword(s):  
High Density Lipoprotein ◽  
Total Cholesterol ◽  
High Density Lipoprotein Cholesterol ◽  
Suicide Risk ◽  
Density Lipoprotein ◽  
High Density ◽  
Lipoprotein Cholesterol ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Cholesterol Levels

The aim of this study was to retrospectively evaluate the role of C-reactive protein, total cholesterol and high-density lipoprotein cholesterol in patients suffering from Major Depression (MD). Data of C-reactive protein, total cholesterol (TC) and high-density lipoprotein cholesterol of 37 adult outpatients (17 men, 20 women) with a DSM-IV diagnosis of MD were analyzed. Depression was measured with the 17-item Hamilton Depression Rating Scale (HAM-D) and with the Beck Depression Inventory (BDI). Suicide risk was evaluated with the Scale of Suicide Ideation (SSI). Patients with a lifetime history of attempted suicide were categorized as having higher suicide risk. Higher suicide risk patients showed higher C-reactive protein levels and lower high-density lipoprotein cholesterol levels than lower suicide risk patients whereas total cholesterol levels were not statistically different. C-reactive protein positively correlated with BDI, HAM-D, SSI scores and with number of previous depressive episodes. High-density lipoprotein cholesterol correlated inversely with BDI, HAM-D and SSI scores, whereas, no significant correlations were found between Total Cholesterol and other variables including C-reactive protein. In linear regression models, C-reactive protein was predictor of more severe depression and increased suicide risk. Lower high-density lipoprotein cholesterol levels were significantly predictive of increased suicide risk.

DYSLIPIDEMIA IN BETA THALASSAEMIA MAJOR PATIENTS

1969 ◽  
Vol 5 (2) ◽  
pp. 695-697
Author(s):  
MUHAMMAD ASIF ◽  
ASMA RASHEED
Keyword(s):  
High Density Lipoprotein ◽  
Lipid Profile ◽  
Total Cholesterol ◽  
Density Lipoprotein ◽  
High Density ◽  
Lipoprotein Cholesterol ◽  
Beta Thalassemia ◽  
Thalassaemia Major ◽  
Beta Thalassaemia ◽  
Cholesterol Levels

BACKGROUND: Beta thalassaemia is the most common frequent hereditary blood disorderthroughout the world. Changes in lipid levels have been seen in different types of beta thalassaemia.OBJECTIVE: The aim of study was to evaluate the lipid profile (serum cholesterol, HDL, LDL, serumtriglyceride) in beta-thalassemia major patients and to compare the lipid profile of beta-thalassemiamajor patients with healthy controlsMATERIALS AND METHODS: In the present study we included clinically diagnosed 45 patients ofbeta thalassaemia major. The levels of Cholesterol, Triglyceride, HDLc, LDLc, VLDLc, were measuredby using latest techniques in clinical biochemistry laboratory.RESULTS: Our study revealed that in thalassaemic patients lipid pattern became altered had high levelof triglyceride, low level of cholesterol and low HDL-cholesterol levels and conclude that thalassaemicpatients are at risk of coronary heart disease .CONCLUSION: Significant variations were found which confirm that lipid changes occur in Bthalassaemic patients when Total cholesterol, Serum triglycerides, Low density lipoprotein cholesterol,high density lipoprotein cholesterol levels are compared with normal healthy subjects. Multiple factorssuch as age, iron overload, hormonal changes and liver injury might cause these changes. As this studyfocus on lipid abnormalities in beta thalassaemia major, this may help clinicians in the management ofsuch patients.KEYWORDS: Total Cholesterol (TC), Triglyceride (TG), High density lipoprotein (HDL), Lowdensity lipoprotein (LDL), Beta thalassaemia major.

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