scholarly journals Ratio of preoperative atrial natriuretic peptide to brain natriuretic peptide predicts the outcome of the maze procedure in mitral valve disease

2013 ◽  
Vol 8 (1) ◽  
Author(s):  
Masafumi Sato ◽  
Akihito Mikamo ◽  
Hiroshi Kurazumi ◽  
Ryo Suzuki ◽  
Masanori Murakami ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Atrial Natriuretic Peptide ◽  
Brain Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Mitral Valve Disease ◽  
Valve Disease ◽  
Maze Procedure ◽  
Atrial Natriuretic

Small Animal Review

2020 ◽  
Vol 25 (3) ◽  
pp. 1-1
Author(s):  
Bryn BVSc PhD MRCVS
Keyword(s):  
Mitral Valve ◽  
Atrial Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Mitral Valve Disease ◽  
Small Animal ◽  
Valve Disease ◽  
Plasma Atrial Natriuretic Peptide ◽  
Echocardiographic Findings ◽  
Atrial Natriuretic

Summary: Plasma atrial natriuretic peptide and troponin concentrations interpreted together are useful in assessing the severity of mitral valve disease in the dog and are useful measures to augment echocardiographic findings.

Brain-natriuretic peptide and cyclic guanosine monophosphate as biomarkers of myxomatous mitral valve disease in dogs

2011 ◽  
Vol 189 (3) ◽  
pp. 349-352 ◽  
Author(s):  
Sophia G. Moesgaard ◽  
Torkel Falk ◽  
Tom Teerlink ◽  
Halldóra H. Guðmundsdóttir ◽  
Sif Sigurðardóttir ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Brain Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Mitral Valve Disease ◽  
Cyclic Guanosine Monophosphate ◽  
Guanosine Monophosphate ◽  
Valve Disease

Biologic variability of N-terminal pro-brain natriuretic peptide in healthy dogs and dogs with myxomatous mitral valve disease

2017 ◽  
Vol 19 (2) ◽  
pp. 124-131 ◽  
Author(s):  
Randolph L. Winter ◽  
Ashley B. Saunders ◽  
Sonya G. Gordon ◽  
Jesse S. Buch ◽  
Matthew W. Miller
Keyword(s):  
Mitral Valve ◽  
Brain Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Mitral Valve Disease ◽  
Valve Disease ◽  
Healthy Dogs

CHANGES IN SERUM CONCENTRATION OF N-TERMINAL PRO-BRAIN NATRIURETIC PEPTIDE AFTER TREATMENT IN TWO DOGS WITH CONGESTIVE HEART FAILURE SECONDARY TO MITRAL VALVE DISEASE

2018 ◽  
Vol 45 (04) ◽  
pp. 129-134
Author(s):  
I.-Ping Chan ◽  
Tung Hsueh ◽  
Wen-Ying Chen
Keyword(s):  
Heart Failure ◽  
Congestive Heart Failure ◽  
Mitral Valve ◽  
Brain Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Mitral Valve Disease ◽  
Valve Disease ◽  
Gradual Decline ◽  
Serial Measurements ◽  
New Onset

Two 8-year-old small-breed neutered dogs were referred due to respiratory distress caused by a new onset of congestive heart failure secondary to degenerative mitral valve disease. Medical treatment, including a diuretic and a vasodilator, was initiated, and blood samples for evaluating the levels of blood urea nitrogen, creatinine, and N-terminal pro-brain natriuretic peptide (NT-proBNP) were collected at every visit. The two dogs had entirely different outcomes: one is still alive with its symptoms well controlled by the medications, whereas the other one was unstable during the therapeutic period and only survived for 89 days after the diagnosis was made. Serial measurements of NT-proBNP concentration revealed that its gradual decline corresponded to better outcome, whereas fluctuant and ascending concentrations reflected a poor prognosis.

Biological effects of rat iso-atrial natriuretic peptide and brain natriuretic peptide are indistinguishable from each other

1992 ◽  
Vol 70 (11) ◽  
pp. 1525-1528 ◽  
Author(s):  
D. A. Wigle ◽  
B. M. Bennett ◽  
D. B. Jennings ◽  
I. R. Sarda ◽  
T. G. Flynn ◽  
...  
Keyword(s):  
Amino Acid ◽  
Atrial Natriuretic Peptide ◽  
Brain Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Receptor Binding ◽  
Amino Acid Substitution ◽  
Cyclic Gmp ◽  
Cardiovascular Response ◽  
Biological Effects ◽  
Atrial Natriuretic

Rat brain natriuretic peptide (rBNP) and iso-atrial natriuretic peptide (iso-rANP) were discovered independently by two research laboratories. They are considered to be members of the B-type natriuretic peptides. Except for the Gln/Leu substitution at position 44, the amino acid sequence of iso-rANP is identical with that of the C-terminal 45 amino acids of rat pro-BNP and with the 5-kDa cardiac peptide from rat atria. To determine whether this amino acid substitution can modify the known biological effects of rBNP and iso-rANP, the present investigation examined the cardiovascular and renal responses, vasorelaxant effect, receptor binding characteristics, and cyclic GMP production by the two peptides in relation to that of rat atrial natriuretic peptide (rANP). Results indicate that rBNP and iso-rANP are indistinguishable from each other in terms of these known biological activities of atrial natriuretic peptide. We therefore conclude that rBNP and iso-rANP are identical peptides and that the amino acid substitution at position 44 represents a polymorphic form of the rat B-type natriuretic peptide.Key words: atrial natriuretic peptide, brain natriuretic peptide, cardiovascular response, vasorelaxation, cyclic GMP, receptor binding.

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