scholarly journals International cohort study of 73 anti-Ku-positive patients: association of p70/p80 anti-Ku antibodies with joint/bone features and differentiation of disease populations by using principal-components analysis

2012 ◽  
Vol 14 (1) ◽  
pp. R2 ◽  
Author(s):  
Katja Lakota ◽  
Gerhard G Thallinger ◽  
Snezna Sodin-Semrl ◽  
Blaz Rozman ◽  
Ales Ambrozic ◽  
...  
2014 ◽  
Vol 18 (8) ◽  
pp. 1436-1443 ◽  
Author(s):  
Tim T Morris ◽  
Kate Northstone

AbstractObjectiveDespite differences in obesity and ill health between urban and rural areas in the UK being well documented, very little is known about differences in dietary patterns across these areas. The present study aimed to examine whether urban/rural status is associated with dietary patterns in a population-based UK cohort study of children.DesignDietary patterns were obtained using principal components analysis and cluster analysis of 3 d diet records collected from children at 10 years of age. Rurality was obtained from the 2001 UK Census urban/rural indicator at the time of dietary assessment. General linear models were used to examine the relationship between rurality and dietary pattern scores from principal components analysis; multinomial logistic regression was used to assess the association between rurality and dietary clusters.SettingThe Avon Longitudinal Study of Parents and Children (ALSPAC), South West England.SubjectsChildren (n 5677) aged 10 years (2817 boys and 2860 girls).ResultsAfter adjustment, increases in rurality were associated with increased scores on the ‘health awareness’ dietary pattern (β=0·35; 95 % CI 0·14, 0·56; P<0·001 for the most rural compared with the most urban group) and lower scores on the ‘packed lunch/snack’ dietary pattern (β=−0·39; 95 % CI −0·59, −0·19; P<0·001 for the most rural compared with the most urban group). The odds ratio for participants being in the ‘healthy’ compared with the ‘processed’ dietary cluster for the most rural areas was 1·61 (95 % CI 1·05, 2·49; P=0·02) compared with those in the most urban areas.ConclusionsThere is evidence to suggest that differences exist in dietary patterns between rural and urban areas. Similar results were found using two different methods of dietary pattern analysis, showing that children residing in rural households were more likely to consume healthier diets than those in urban households.


1980 ◽  
Vol 19 (04) ◽  
pp. 205-209
Author(s):  
L. A. Abbott ◽  
J. B. Mitton

Data taken from the blood of 262 patients diagnosed for malabsorption, elective cholecystectomy, acute cholecystitis, infectious hepatitis, liver cirrhosis, or chronic renal disease were analyzed with three numerical taxonomy (NT) methods : cluster analysis, principal components analysis, and discriminant function analysis. Principal components analysis revealed discrete clusters of patients suffering from chronic renal disease, liver cirrhosis, and infectious hepatitis, which could be displayed by NT clustering as well as by plotting, but other disease groups were poorly defined. Sharper resolution of the same disease groups was attained by discriminant function analysis.


2020 ◽  
Vol 6 (2) ◽  
pp. 151-183
Author(s):  
Diana B. Archangeli ◽  
Jonathan Yip

AbstractBased on impressionistic and acoustic data, Assamese is described as having a phonological tongue root harmony system, with blocking by certain phonological configurations and over-application in certain morphological contexts. This study explores physical properties of the patterns using ultrasonic imaging to determine whether the impressionistic descriptions match what speakers actually do. Principal components analysis (PCA) determines that most participants produce a contrast in tongue root position in the appropriate contexts, though there is less of an impact on tongue root with greater distance from the triggering vowel. Analysis uses the root mean squared distance (RMSD) calculation to determine whether both blocking and over-application take effect. The blocking results conform to the impressionistic descriptions. With over-application, [e] and [o] are expected; while some speakers clearly produce these vowels, others articulate a vowel that is indeterminant between the expected [e]/[o] and an unexpected [ɛ]/[ɔ]. No speaker consistently showed the expected tongue root position in all contexts, and some speakers appeared to have lost the contrast entirely, yet all are considered to be speakers of the same dialect of Assamese. Whether this (apparent) loss is a consequence of crude research methodologies or accurately reflects what is happening within the language community remains an open question.


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