scholarly journals Good outcome in noncoronary out-of-hospital cardiac arrest treated with mild induced hypothermia

Critical Care ◽  
2009 ◽  
Vol 13 (Suppl 1) ◽  
pp. P72
Author(s):  
M Busch
Resuscitation ◽  
2014 ◽  
Vol 85 (5) ◽  
pp. 657-663 ◽  
Author(s):  
Clifton W. Callaway ◽  
Robert H. Schmicker ◽  
Siobhan P. Brown ◽  
J. Michael Albrich ◽  
Douglas L. Andrusiek ◽  
...  

Critical Care ◽  
2007 ◽  
Vol 11 (4) ◽  
pp. 420 ◽  
Author(s):  
Bhavesh M Patel ◽  
Alyssa B Chapital ◽  
Mohamed Y Rady ◽  
Joel S Larson

Circulation ◽  
2018 ◽  
Vol 138 (Suppl_2) ◽  
Author(s):  
Shinichi Ijuin ◽  
Akihiko Inoue ◽  
Nobuaki Igarashi ◽  
Shigenari Matsuyama ◽  
Tetsunori Kawase ◽  
...  

Introduction: We have reported previously a favorable neurological outcome by extracorporeal cardiopulmonary resuscitation (ECPR) for out of hospital cardiac arrest. However, effects of ECPR on patients with prolonged pulseless electrical activity (PEA) are unclear. We analyzed etiology of patients with favorable neurological outcomes after ECPR for PEA with witness. Methods: In this single center retrospective study, from January 2007 to May 2018, we identified 68 patients who underwent ECPR for PEA with witness. Of these, 13 patients (19%) had good neurological outcome at 1 month (Glasgow-Pittsburgh Cerebral Performance Category (CPC):1-2, Group G), and 55 patients (81%) had unfavorable neurological outcome (CPC:3-5, Group B). We compared courses of treatment and causes/places of arrests between two groups. Results are expressed as mean ± SD. Results: Patient characteristics were not different between the two groups. Time intervals from collapse to induction of V-A ECMO were also not significantly different (Group G; 46.1 ± 20.2 min vs Group B; 46.8 ± 21.7 min, p=0.92). Ten patients achieved favorable neurological outcome among 39 (26%) with non-cardiac etiology. In cardiac etiology, only 3 of 29 patients (9%) had a good outcome at 1 month (p=0.08). In particular, 5 patients of 10 pulmonary embolism, and 4 of 4 accidental hypothermia responded well to ECPR with a favorable neurological outcome. Additionally, 6 of 13 (46%), who had in hospital cardiac arrest, had good outcome, whereas 7 of 55 (15%) who had out of hospital cardiac arrest, had good outcome (p=0.02). Conclusions: In our small cohort of cardiac arrest patients with pulmonary embolism or accidental hypothermia and PEA with witness, EPCR contributed to favorable neurological outcomes at 1 month.


2006 ◽  
Vol 29 (12) ◽  
pp. 525-529 ◽  
Author(s):  
Brook D. Scott ◽  
Tammy Hogue ◽  
Mark S. Fixley ◽  
Philip B. Adamson

2009 ◽  
Vol 20 (4) ◽  
pp. 343-355
Author(s):  
Staci McKean

The use of induced hypothermia has been considered for treatment of head injuries since the 1900s. However, it was not until 2 landmark studies were published in 2002 that induced hypothermia was considered best practice for patients after cardiac arrest. In 2005, the American Heart Association included recommendations in the postresuscitation support guidelines recommending consideration of mild hypothermia for unconscious adult patients with return of spontaneous circulation following out-of-hospital cardiac arrest due to ventricular fibrillation. This article provides an overview on the history and supportive research for inducing mild hypothermia after cardiac arrest, the pathophysiology associated with cerebral ischemia occurring with hypothermia, nursing management for this patient population, and the development of a protocol for induced hypothermia after cardiac arrest.


2015 ◽  
Vol 47 (9) ◽  
pp. 860-866 ◽  
Author(s):  
M Ørbo ◽  
P Aslaksen ◽  
K Larsby ◽  
C Schäfer ◽  
P Tande ◽  
...  

2011 ◽  
Vol 2011 ◽  
pp. 1-7 ◽  
Author(s):  
Pascal Stammet ◽  
Yvan Devaux ◽  
Francisco Azuaje ◽  
Christophe Werer ◽  
Christiane Lorang ◽  
...  

Objective. Determine the potential of procalcitonin (PCT) to predict neurological outcome after hypothermia treatment following cardiac arrest.Methods. Retrospective analysis of patient data over a 2-year period. Mortality and neurological outcome of survivors were determined 6 months after cardiac arrest using the Cerebral Performance Category (CPC) score.Results. Data from 53 consecutive patients were analyzed. Median age was 63 (54–71) and 79% were male. Twenty-seven patients had good outcome (CPC ≤ 2) whereas 26 had severe neurological sequelae or died (CPC 3–5). At 48 h, after regaining normothermia, PCT was significantly higher in patients with bad outcome compared to those with good outcome: 3.38 (1.10–24.48) versus 0.28 (0–0.75) ng/mL (). PCT values correlated with bad neurological outcome (, ) and predicted outcome with an area under the curve of 0.84 (95% CI 0.73–0.96). A cutoff point of 1 ng/mL provided a sensitivity of 85% and a specificity of 81%. Above a PCT level of 16 ng/mL, no patient regained consciousness. PCT provided an additive value over simplified acute physiology score II.Conclusions. PCT might be an ancillary marker for outcome prediction after cardiac arrest treated by induced hypothermia.


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