scholarly journals Tissue hemoglobin index: a non-invasive optical measure of total tissue hemoglobin

Critical Care ◽  
2009 ◽  
Vol 13 (Suppl 5) ◽  
pp. S2 ◽  
Author(s):  
Dean Myers ◽  
Michelle McGraw ◽  
Mark George ◽  
Kristine Mulier ◽  
Greg Beilman

Circulation ◽  
2015 ◽  
Vol 132 (suppl_3) ◽  
Author(s):  
Takeji Saitoh ◽  
Hiroshi Satoh ◽  
Naohiro Kanayama ◽  
Masatsugu Niwayama ◽  
Hironao Hozumi ◽  
...  

Introduction: In patients with poor general conditions, the conventional pulse oximetry is sometimes unable to determine the oxygen saturation because of peripheral arteriole constriction. The near infra-red spectroscopy (NIRS) can measure absolute concentration of oxygenated, deoxygenated, and total tissue hemoglobin. Purpose: This study aimed to investigate the potential of a novel minimized NIRS system in terms of measurements of tissue oxygen and hemoglobin. Methods: We enrolled 22 normal controls and 83 emergency patients who came to the emergency department with poor general conditions. The tissue oxygen saturation (StO2) and tissue hemoglobin index (T-HbI) on second finger pulp (SFP), thenar eminence (TE), and sternocleid muscle (SM) were measured in both groups. Results: (1) In all subjects including patients with cardio-pulmonary arrest, both the StO2 and T-Hbl values were obtained stably. (2) In the emergency patients, the StO2 value on SFP was lower than those on TE and SM (53% [49-56] vs. 57% [55-60] and 58% [53-62], median [inter-quartile range], p<0.01), whereas those in the normal controls were not different. The StO2 value on SFP was lower in the emergency patients than that in normal controls (60% [58-61], p<0.01). (3) In the emergency patients, the T-Hbl value on SBP was also lower than those on TE and SM (0.13 mM [0.11-0.15] vs. 0.25 [0.22-0.29] and 0.23 [0.18-0.29], p<0.01). The T-HbI value on SFP was also lower in the emergency patients than that in normal controls (0.18 mM [0.17-0.21], p<0.01). Conclusion: NIRS detected peripheral circulatory failure easily and immediately in the emergency patients.



Author(s):  
H.W. Deckman ◽  
B.F. Flannery ◽  
J.H. Dunsmuir ◽  
K.D' Amico

We have developed a new X-ray microscope which produces complete three dimensional images of samples. The microscope operates by performing X-ray tomography with unprecedented resolution. Tomography is a non-invasive imaging technique that creates maps of the internal structure of samples from measurement of the attenuation of penetrating radiation. As conventionally practiced in medical Computed Tomography (CT), radiologists produce maps of bone and tissue structure in several planar sections that reveal features with 1mm resolution and 1% contrast. Microtomography extends the capability of CT in several ways. First, the resolution which approaches one micron, is one thousand times higher than that of the medical CT. Second, our approach acquires and analyses the data in a panoramic imaging format that directly produces three-dimensional maps in a series of contiguous stacked planes. Typical maps available today consist of three hundred planar sections each containing 512x512 pixels. Finally, and perhaps of most import scientifically, microtomography using a synchrotron X-ray source, allows us to generate maps of individual element.



2001 ◽  
Vol 120 (5) ◽  
pp. A266-A266
Author(s):  
R BUTLER ◽  
B ZACHARAKIS ◽  
D MOORE ◽  
K CRAWFORD ◽  
G DAVIDSON ◽  
...  


2001 ◽  
Vol 120 (5) ◽  
pp. A491-A491 ◽  
Author(s):  
A LEODOLTER ◽  
D VAIRA ◽  
F BAZZOLL ◽  
A HIRSCHL ◽  
F MEGRAUD ◽  
...  
Keyword(s):  


2020 ◽  
Vol 158 (6) ◽  
pp. S-1249
Author(s):  
Yuri Hanada ◽  
Juan Reyes Genere ◽  
Bryan Linn ◽  
Tiffany Mangels-Dick ◽  
Kenneth K. Wang


2007 ◽  
Vol 177 (4S) ◽  
pp. 430-430
Author(s):  
Ram Ganapathi ◽  
Troy R. Gianduzzo ◽  
Arul Mahadevan ◽  
Monish Aron ◽  
Lee E. Ponsky ◽  
...  


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