scholarly journals Optical coherence tomography features and risk of macular hole formation in the fellow eye

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Birger Lindtjørn ◽  
Jørgen Krohn ◽  
Vegard A. Forsaa
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Hole ◽  
Disease Risk ◽  
Posterior Vitreous Detachment ◽  
Optical Coherence ◽  
Multiple Testing Correction ◽  
Fellow Eye ◽  
Bilateral Group ◽  
Increased Risk ◽  
Unilateral Group

Abstract Background To investigate the risk of primary macular hole (MH) in the fellow eye, and to evaluate baseline characteristics and optical coherence tomography (OCT) features that precede MH formation in the fellow eye. Methods A retrospective review of 229 patients treated for primary MH at Stavanger University Hospital, Norway, from January 2008 through December 2018. The patients were categorised into two groups according to subsequent development of MH in the fellow eye. The OCT findings of the two groups were compared, and associated risk factors for MH formation assessed. Results Twenty cases of bilateral MH were identified. The overall bilateral disease risk was 8.8% (95% CI, 5.8–13.2%). Two patients were previously operated in the fellow eye, six patients presented with bilateral MH, and 12 patients subsequently developed MH in the fellow eye. The risk of subsequent MH development was 5.7% (95% CI, 3.3–9.8%). Although the extent of posterior vitreous detachment (PVD) tended to be more progressed in the bilateral group compared with the unilateral group, the difference was not statistically significant. In the bilateral group, 41.7% had outer retinal defects vs 6.6% in the unilateral group (p = 0.001), and 33.3% in the bilateral group had intraretinal pseudocysts vs 10.2% in the unilateral group (p = 0.036, not significant after multiple testing correction). Conclusion Outer retinal defects and intraretinal pseudocysts are associated with an increased risk of MH formation in the fellow eye, and complete PVD indicates a decreased risk of MH formation.

Optical Coherence Tomography Evaluation of Idiopathic Macular Hole Treatment by Gas-assisted Posterior Vitreous Detachment

2006 ◽  
Vol 142 (5) ◽  
pp. 869-871 ◽  
Author(s):  
Rodrigo Jorge ◽  
Rogério A. Costa ◽  
José A. Cardillo ◽  
Fausto Uno ◽  
Pedro P. Bonomo ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Hole ◽  
Posterior Vitreous Detachment ◽  
Optical Coherence ◽  
Idiopathic Macular Hole ◽  
Vitreous Detachment

Optical coherence tomography evaluation of idiopathic macular hole treatment by gas-assisted posterior vitreous detachment

2001 ◽  
Vol 132 (2) ◽  
pp. 264-266 ◽  
Author(s):  
Rogério A. Costa ◽  
José A. Cardillo ◽  
Paulo H. Morales ◽  
Rodrigo Jorge ◽  
Fausto Uno ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Hole ◽  
Posterior Vitreous Detachment ◽  
Optical Coherence ◽  
Idiopathic Macular Hole ◽  
Vitreous Detachment

OPTICAL COHERENCE TOMOGRAPHY DOCUMENTATION OF SPONTANEOUS MACULAR HOLE CLOSURE WITHOUT POSTERIOR VITREOUS DETACHMENT

Retina ◽  
2002 ◽  
Vol 22 (4) ◽  
pp. 506-509 ◽  
Author(s):  
K. BAILEY FREUND ◽  
ANTONIO P. CIARDELLA ◽  
VIRAL SHAH ◽  
LAWRENCE A. YANNUZZI ◽  
YALE A. FISHER
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Hole ◽  
Posterior Vitreous Detachment ◽  
Optical Coherence ◽  
Vitreous Detachment ◽  
Hole Closure

scholarly journals Spontaneous disappearance and recurrence of impending macular hole: a case report

2019 ◽  
Vol 13 (1) ◽  
Author(s):  
Makiko Miyamoto ◽  
Kazuhiro Shimizu ◽  
Yohei Sato ◽  
Bunsei Konose ◽  
Natsuko Mano ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Visual Acuity ◽  
Macular Hole ◽  
Posterior Vitreous Detachment ◽  
Unknown Origin ◽  
Optical Coherence ◽  
Initial Examination ◽  
Vitreous Traction ◽  
Old Japanese ◽  
Spontaneous Disappearance

Abstract Background There have been several reports of spontaneous closure and reopening of a macular hole, however, in most of those cases, it was observed in eyes post vitrectomy. Here, we report a case of multiple episodes of spontaneous disappearance and recurrence of impending macular hole (stage 1B macular hole) with no history of previous surgery. Case presentation A 76-year-old Japanese man presented with a primary complaint of reduced visual acuity in his right eye. On initial examination, the visual acuity in his right and left eye was 0.4 and 0.01, respectively. He had previously been diagnosed as having macular degeneration of unknown origin in his left eye. Optical coherence tomography imaging confirmed vitreomacular traction and impending macular hole in his right eye. After a 1-week follow-up period, posterior vitreous detachment was detected, and the impending macular hole appeared to be resolved. Two months later, the impending macular hole had completely disappeared and his visual acuity had improved to 0.9. Six months later, he again noticed decreased vision in his right eye. An examination revealed that his visual acuity had dropped to 0.4, and there was a recurrence of impending macular hole. An optical coherence tomography examination showed no definitive findings of vitreous traction, and, 1 month later, spontaneous disappearance was observed again and his visual acuity improved to 0.7. Conclusions In this case, both the initial onset and the recurrence involved impending macular hole, however, the optical coherence tomography findings differed at each examination. These findings suggest that some causes other than vitreous traction were responsible for both the spontaneous disappearance and recurrence of the impending macular hole in this present case.

Mapping posterior vitreous detachment by optical coherence tomography in eyes with idiopathic macular hole

2003 ◽  
Vol 135 (3) ◽  
pp. 351-355 ◽  
Author(s):  
Yasuki Ito ◽  
Hiroko Terasaki ◽  
Toshimitsu Suzuki ◽  
Takeshi Kojima ◽  
Masako Mori ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Hole ◽  
Posterior Vitreous Detachment ◽  
Optical Coherence ◽  
Idiopathic Macular Hole ◽  
Vitreous Detachment

Abstract 15219: Fully Automated Calcification Segmentation in Intravascular Optical Coherence Tomography Images Using a Two-step Deep Learning Approach

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Juhwan Lee ◽  
Yazan Gharaibeh ◽  
Vladislav N Zimin ◽  
Luis A Dallan ◽  
Hiram G Bezerra ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Deep Learning ◽  
Learning Approach ◽  
Optical Coherence ◽  
Stent Deployment ◽  
Automated Method ◽  
Increased Risk ◽  
Maximum Angle ◽  
Intravascular Optical Coherence Tomography ◽  
Sensitivity Specificity

Introduction: Major calcifications are of great concern when performing percutaneous coronary intervention as they hinder stent deployment. Calcifications can lead to under-expansion and strut malapposition, with increased risk of thrombosis and in-stent restenosis. Therefore, accurate identification, visualization, and quantification of calcifications are important. Objective: In this study, we developed a 2-step deep learning approach to enable segmentation of major calcifications in a typical 500+ frame intravascular optical coherence tomography (IVOCT) images. Methods: The dataset consisted of a total of 12,551 IVOCT frames across 68 patients with 68 pullbacks. We applied a series of pre-processing steps including guidewire/shadow removal, lumen detection, pixel shifting, and Gaussian filtering. To detect the major calcifications in step 1, we implemented the 3D convolutional neural network consisting of 5 convolutional, 5 max-pooling, and 2 fully-connected layers. In step-2, SegNet deep learning model was used to segment calcified plaques. In both steps, classification errors were reduced using conditional random field. Results: Step-1 reliably identified major calcifications (sensitivity/specificity: 97.7%/87.7%). Semantic segmentation of calcifications following step-2 was typically visually quite good (Fig. 1) with (sensitivity/specificity: 86.2%/96.7%). Our method was superior to a single step approach and showed excellent reproducibility on repetitive IVOCT pullbacks, with very small differences of clinically relevant attributes (maximum angle, maximum thickness, and length) and the exact same IVOCT calcium scores for assessment of stent deployment. Conclusions: We developed the fully-automated method for identifying calcifications in IVOCT images based on a 2-step deep learning approach. Extensive analyses indicate that our method is very informative for both live-time treatment planning and research purposes.

scholarly journals Optical Coherence Tomography Findings in Idiopathic Macular Holes

2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
Lynn L. Huang ◽  
David H. Levinson ◽  
Jonathan P. Levine ◽  
Umar Mian ◽  
Irena Tsui
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Hole ◽  
Clinical Assessment ◽  
Chart Review ◽  
Subretinal Fluid ◽  
Optical Coherence ◽  
Cross Sectional ◽  
Macular Holes ◽  
Idiopathic Macular Holes ◽  
Intraretinal Cysts

Purpose. To describe the characteristics of idiopathic macular holes (MH) on optical coherence tomography (OCT) and correlate OCT with clinical assessment.Design. Cross-sectional chart review and OCT assessment.Participants. Sixty-seven eyes with a clinically diagnosed idiopathic MH with available OCT data.Methods. A retrospective chart review and OCT assessment.Results. Based on OCT grading, 40 eyes had a full-thickness macular hole (FTMH) and 21 eyes had a lamellar macular hole (LMH). Clinical exam and OCT assessment agreed in 53 (87%) eyes when assessing the extent of MH. Six eyes (14.6%) in the FTMH group, and 3 eyes in the LMH group (14.3%) had persistent vitreomacular traction. Thirty-seven eyes (92.5%) in the FTMH group and 11 eyes (52.4%) in the LMH group had associated intraretinal cysts. Two eyes (5.0%) in the FTMH group and zero eyes in the LMH group had subretinal fluid. Intraretinal cysts were found to be more frequently associated with FTMH than with LMH (P<0.001).Conclusion. This paper described OCT findings in a group of patients with clinically diagnosed MH. A high level of correlation between clinical assessment and OCT findings of LMH and FTMH was observed, and intraretinal cysts were often present in FTMH.

Morphofunctional analysis of the retina in the surgical treatment of idiopathic macular holes

2021 ◽  
pp. 48-52
Author(s):  
A.S. Zotov ◽  
◽  
A.S. Balalin ◽  
S.V. Balalin ◽  
S.M. Purshak ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Surgical Treatment ◽  
Macular Hole ◽  
Practical Importance ◽  
Functional Results ◽  
Hole Diameter ◽  
Optical Coherence ◽  
Macular Holes ◽  
Idiopathic Macular Holes ◽  
Morphofunctional Analysis

Purpose. To evaluate the role of microperimetry and optical coherence tomography (OCT) in the morphofunctional analysis of the retina after surgical treatment of idiopathic macular holes (IMH). Materials and methods. A retrospective study of 33 patient's treatment results (33 eyes) with IMH was carried out. All patients underwent minimally invasive with 25G or 27G vitrectomy. Best corrected visual acuity (BCVA), macular photosensitivity, fixation stability, macular neuroepithelial (NE) volume and minimal macular hole diameter were analyzed. Follow-up period: 6 months. Results. A complete closure of the macular hole was achieved in all cases post-op. The patients had reliable improvement of BCVA, retinal photosensitivity and decrease of macular NE volume. Based on a multifactor correlation analysis with the purpose to predict the results of surgical treatment, the dependence of post-op BCVA on the pre-op photosensitivity of the retina and the minimal diameter of the macular hole was revealed. Conclusions. Microperimetry and OCT are modern non-invasive research methods allowing to estimate anatomical and functional results of surgical IMH treatment. The study of retinal photosensitivity in the macula and minimal macular hole diameter pre-op allows to predict post-op BCVA, which has a practical importance. Keywords: idiopathic macular hole, vitrectomy, microperimetry, optical coherence tomography.

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