Paradoxical physiological responses to propranolol in a Rett syndrome patient: a case report

Purpose Misophonia is a sound tolerance disorder condition in certain sounds that trigger intense emotional or physiological responses. While some persons may experience misophonia, a few patients suffer from misophonia. However, there is a dearth of literature on audiological assessment and management of persons with misophonia. The purpose of this report is to discuss the assessment of misophonia and highlight the management option that helped a patient with misophonia. Method A case study of a 26-year-old woman with the complaint of decreased tolerance to specific sounds affecting quality of life is reported. Audiological assessment differentiated misophonia from hyperacusis. Management included retraining counseling as well as desensitization and habituation therapy based on the principles described by P. J. Jastreboff and Jastreboff (2014). A misophonia questionnaire was administered at regular intervals to monitor the effectiveness of therapy. Results A detailed case history and audiological evaluations including pure-tone audiogram and Johnson Hyperacusis Index revealed the presence of misophonia. The patient benefitted from intervention, and the scores of the misophonia questionnaire indicated a decrease in the severity of the problem. Conclusions It is important to differentially diagnose misophonia and hyperacusis in persons with sound tolerance disorders. Retraining counseling as well as desensitization and habituation therapy can help patients who suffer from misophonia.

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A case report of atlanto-axial instability in a Down Syndrome patient

Spinal Cord Series and Cases ◽

10.1038/s41394-018-0139-7 ◽

2018 ◽

Vol 4 (1) ◽

Author(s):

Mubashir Alavi Jusabani ◽

Sakina Mehboob Rashid ◽

Honest Herman Massawe ◽

William Patrick Howlett ◽

Marieke Cornelia Johanna Dekker

Keyword(s):

Down Syndrome ◽

Case Report ◽

Syndrome Patient ◽

Down Syndrome Patient

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A Case Study on Management of Rett Syndrome by Wholistic approach

International Journal of Ayurvedic Medicine ◽

10.47552/ijam.v11i2.1403 ◽

2020 ◽

Vol 11 (2) ◽

pp. 351-357

Author(s):

Renu Rathi ◽

Bharat Rathi ◽

Rakesh Khatana ◽

Suraj Sankh

Keyword(s):

Case Report ◽

Rett Syndrome ◽

Motor Development ◽

Autism Spectrum ◽

Severe Form ◽

Fine Motor ◽

Gross Motor ◽

Gross Motor Development

Background: Rett syndrome-RS comes under Autism spectrum disorder-ASD which is a neurodevelopmental syndrome. It is diagnosed by the main differentiating features of lack of interpersonal and communication skills, poor eye contact, delayed speech with pervasive abnormal body movements. Aim and Objectives: This case report is aimed at dissemination of comprehensive role of Ayurveda in management of ASD, Rett syndrome. Material and Methods: RS is the severe form of ASD. This case study of 2.3 year’s girl presented with RS and global delay, being treated with wholistic approach. It comprises Ayurveda chikitsa and other therapies like Yoga, hydrotherapy, occupational, music, physiotherapy and many more. Observation and Result: Patient has shown promising results in all developmental milestones such as gross motor, fine motor and personal social in 6 months duration except language. Different varieties of massage therapy, diet and Basti, Nasya (Panchkarma) procedures, Omkar mantra chanting, passive Yogasana were done. Conclusion: In this case report, mainly Ayurveda interventions were implemented with wholistic approach as an adjuvant, received good result in gross motor development which is very difficult in RS, hence it is a unique case. It also opened the door of wholistic approach with the hope to deliver the good result in similar disorders.

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