scholarly journals Clinical phenotypes and heath-related quality of life of COPD patients in a rural setting in Malaysia – a cross-sectional study

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Chee-Shee Chai ◽  
Sumastika Bt Mos ◽  
Diana-Leh-Ching Ng ◽  
Greta-Miranda-Kim-Choo Goh ◽  
Anselm-Ting Su ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cross Sectional Study ◽  
Rural Setting ◽  
Chronic Obstructive ◽  
Sectional Study ◽  
Cross Sectional ◽  
Exacerbation Frequency ◽  
Copd Patients ◽  
Related Quality

Abstract Background The Spanish chronic obstructive pulmonary disease (COPD) guideline phenotypes patients according to the exacerbation frequency and COPD subtypes. In this study, we compared the patients’ health-related quality of life (HRQoL) according to their COPD phenotypes. Methods This was a cross-sectional study of COPD patients who attended the outpatient clinic of the Serian Divisional Hospital and Bau District Hospital from 23th January 2018 to 22th January 2019. The HRQoL was assessed using modified Medical Research Council (mMRC), COPD Assessment Test (CAT), and St George’s Respiratory Questionnaire for COPD (SGRQ-c). Results Of 185 patients, 108 (58.4%) were non-exacerbators (NON-AE), 51 (27.6%) were frequent exacerbators (AE), and the remaining 26 (14.1%) had asthma-COPD overlap (ACO). Of AE patients, 42 (82.4%) had chronic bronchitis and only 9 (17.6%) had emphysema. Of the 185 COPD patients, 65.9% had exposure to biomass fuel and 69.1% were ex- or current smokers. The scores of mMRC, CAT, and SGRQ-c were significantly different between COPD phenotypes (p <  0.001). There were significantly more patients with mMRC 2–4 among AE (68.6%) (p <  0.001), compared to those with ACO (38.5%) and NON-AE (16.7%). AE patients had significantly higher total CAT (p = 0.003; p <  0.001) and SGRQ-c (both p <  0.001) scores than those with ACO and NON-AE. Patients with ACO had significantly higher total CAT and SGRQ-c (both p <  0.001) scores than those with NON-AE. AE patients had significantly higher score in each item of CAT and component of SGRQ-c compared to those with NON-AE (all p <  0.001), and ACO [(p = 0.003–0.016; p = < 0.001–0.005) except CAT 1, 2 and 7. ACO patients had significantly higher score in each item of CAT and component of SGRQ-c (p = < 0.001–0.040; p <  0.001) except CAT 2 and activity components of SGRQ-c. Conclusions The HRQoL of COPD patients was significantly different across different COPD phenotypes. HRQoL was worst in AE, followed by ACO and NON-AE. This study supports phenotyping COPD patients based on their exacerbation frequency and COPD subtypes. The treatment of COPD should be personalised according to these two factors.

scholarly journals Clinical Phenotypes and Heath-Related Quality of Life of COPD Patients in a Rural Setting in Malaysia – A Cross-Sectional Study

2020 ◽  
Author(s):  
Chee-Shee Chai ◽  
Sumastika Bt Mos ◽  
Diana-Leh-Ching Ng ◽  
Greta-Miranda-Kim-Choo Goh ◽  
Anselm-Ting Su ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cross Sectional Study ◽  
Rural Setting ◽  
Chronic Obstructive ◽  
Sectional Study ◽  
Cross Sectional ◽  
Exacerbation Frequency ◽  
Copd Patients ◽  
Related Quality

Abstract Background:The Spanish chronic obstructive pulmonary disease (COPD) guideline phenotypes patients according to the exacerbation frequency and COPD subtypes. In this study, we compared the patients’ health-related quality of life (HRQoL) according to their COPD phenotypes.Methods:This was a cross-sectional study of COPD patients who attended the outpatient clinic of the Serian Divisional Hospital and Bau District Hospital from 23th January 2018 to 22th January 2019. The HRQoL was assessed using modified Medical Research Council (mMRC), COPD Assessment Test (CAT), and St George's Respiratory Questionnaire for COPD (SGRQ-c). Results:Of 185 patients, 108 (58.4%) were non-exacerbators (NON-AE), 51 (27.6%) were frequent exacerbators (AE), and the remaining 26 (14.1%) had asthma-COPD overlap (ACO). Of AE patients, 42 (82.4%) had chronic bronchitis and only 9 (17.6%) had emphysema. Of the COPD patients, 65.9% had exposure to biomass fuel and 69.1% were ex- or current smokers. The scores of mMRC, CAT, and SGRQ-c were significantly different between COPD phenotypes (p < 0.001). There were significantly more patients with mMRC 2 – 4 among AE (68.6%) (p < 0.001), compared to those with ACO (38.5%) and NON-AE (16.7%). AE patients had significantly higher total CAT (p = 0.003; p < 0.001) and SGRQ-c (both p < 0.001) scores than those with ACO and NON-AE. Patients with ACO also had significantly higher total CAT and SGRQ-c (both p < 0.001) scores than those with NON-AE. AE patients had significantly higher score in each item of CAT and component of SGRQ-c compared to those with NON-AE (all p < 0.001), and ACO [(p = 0.003 – 0.016; p = < 0.001 – 0.005) except CAT 1, 2 and 7. ACO patients had significantly higher score in each item of CAT and component of SGRQ-c (p = < 0.001 – 0.040; p < 0.001) except CAT 2 and activity components of SGRQ-c.Conclusions:The HRQoL of COPD patients was significantly different across COPD phenotypes. HRQoL was worst in AE, followed by ACO and NON-AE. This study supports phenotyping COPD patients based on their exacerbation frequency and COPD subtypes. The treatment of COPD should be personalised according to these two factors.

scholarly journals Clinical Phenotypes and Heath-Related Quality of Life of COPD Patients in a Rural Setting in Malaysia – A Cross-Sectional Study

2020 ◽  
Author(s):  
Chee-Shee Chai ◽  
Sumastika Bt Mos ◽  
Diana-Leh-Ching Ng ◽  
Greta-Miranda-Kim-Choo Goh ◽  
Anselm-Ting Su ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cross Sectional Study ◽  
Rural Setting ◽  
Chronic Obstructive ◽  
Sectional Study ◽  
Cross Sectional ◽  
Exacerbation Frequency ◽  
Copd Patients ◽  
Related Quality

Abstract Background: The Spanish chronic obstructive pulmonary disease (COPD) guideline phenotypes patients according to the exacerbation frequency and COPD subtypes. In this study, we compared the patients’ health-related quality of life (HRQoL) according to their COPD phenotypes.Methods: This was a cross-sectional study of COPD patients who attended the outpatient clinic of the Serian Divisional Hospital and Bau District Hospital from 23th January 2018 to 22th January 2019. The HRQoL was assessed using modified Medical Research Council (mMRC), COPD Assessment Test (CAT), and St George's Respiratory Questionnaire for COPD (SGRQ-c). Results: Of 185 patients, 108 (58.4%) were non-exacerbators (NON-AE), 51 (27.6%) were frequent exacerbators (AE), and the remaining 26 (14.1%) had asthma-COPD overlap (ACO). Of AE patients, 42 (82.4%) had chronic bronchitis and only 9 (17.6%) had emphysema. Of the 185 COPD patients, 65.9% had exposure to biomass fuel and 69.1% were ex- or current smokers. The scores of mMRC, CAT, and SGRQ-c were significantly different between COPD phenotypes (p < 0.001). There were significantly more patients with mMRC 2 – 4 among AE (68.6%) (p < 0.001), compared to those with ACO (38.5%) and NON-AE (16.7%). AE patients had significantly higher total CAT (p = 0.003; p < 0.001) and SGRQ-c (both p < 0.001) scores than those with ACO and NON-AE. Patients with ACO had significantly higher total CAT and SGRQ-c (both p < 0.001) scores than those with NON-AE. AE patients had significantly higher score in each item of CAT and component of SGRQ-c compared to those with NON-AE (all p < 0.001), and ACO [(p = 0.003 – 0.016; p = < 0.001 – 0.005) except CAT 1, 2 and 7. ACO patients had significantly higher score in each item of CAT and component of SGRQ-c (p = < 0.001 – 0.040; p < 0.001) except CAT 2 and activity components of SGRQ-c.Conclusions: The HRQoL of COPD patients was significantly different across different COPD phenotypes. HRQoL was worst in AE, followed by ACO and NON-AE. This study supports phenotyping COPD patients based on their exacerbation frequency and COPD subtypes. The treatment of COPD should be personalised according to these two factors.

scholarly journals Clinical Phenotypes and Heath-Related Quality of Life of COPD Patients in a Rural Setting in Malaysia – A Cross-Sectional Study

2020 ◽  
Author(s):  
Chee-Shee Chai ◽  
Sumastika Bt Mos ◽  
Diana-Leh-Ching Ng ◽  
Greta-Miranda-Kim-Choo Goh ◽  
Anselm-Ting Su ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cross Sectional Study ◽  
Rural Setting ◽  
Chronic Obstructive ◽  
Sectional Study ◽  
Cross Sectional ◽  
Exacerbation Frequency ◽  
Copd Patients ◽  
Related Quality

Abstract Background The Spanish chronic obstructive pulmonary disease (COPD) guideline phenotypes patients according to the exacerbation frequency and COPD subtypes. In this study, we compared the patients’ health-related quality of life (HRQoL) according to their COPD phenotypes. Methods This was a cross-sectional study of COPD patients who attended the outpatient clinic of the Serian Divisional Hospital and Bau District Hospital from 23 th January 2018 to 22 th January 2019. The HRQoL was assessed using modified Medical Research Council (mMRC), COPD Assessment Test (CAT), and St George's Respiratory Questionnaire for COPD (SGRQ-c). Results Of 185 patients, 108 (58.4%) were non-exacerbators (NON-AE), 51 (27.6%) were frequent exacerbators (AE), and the remaining 26 (14.1%) had asthma-COPD overlap (ACO). Of AE patients, 42 (82.4%) had chronic bronchitis and only 9 (17.6%) had emphysema. Of the COPD patients, 65.9% had exposure to biomass fuel. The scores of mMRC, CAT, and SGRQ-c were significantly different between COPD phenotypes (p < 0.001). There were significantly more patients with mMRC 2 – 4 among AE (68.6%) (p < 0.001), compared to those with ACO (38.5%) and NON-AE (16.7%). AE patients had significantly higher total CAT (p = 0.003; p < 0.001) and SGRQ-c (both p < 0.001) scores than those with ACO and NON-AE. Patients with ACO also had significantly higher total CAT and SGRQ-c (both p < 0.001) scores than those with NON-AE. AE patients had significantly higher score in each item of CAT and component of SGRQ-c compared to those with NON-AE (all p < 0.001), and ACO [(p = 0.003 – 0.016; p = < 0.001 – 0.005) except CAT 1, 2 and 7. ACO patients had significantly higher score in each item of CAT and component of SGRQ-c (p = < 0.001 – 0.040; p < 0.001) except CAT 2 and activity components of SGRQ-c. Conclusions The HRQoL of COPD patients was significantly different across COPD phenotypes. HRQoL was worst in AE, followed by ACO and NON-AE. This study supports phenotyping COPD patients based on their exacerbation frequency and COPD subtypes. The treatment of COPD should be personalised according to these two factors.

scholarly journals Health related quality of life in COPD patients: a cross-sectional study

2018 ◽  
Vol 5 (5) ◽  
pp. 2038
Author(s):  
Nilam C. Gaude ◽  
Archana M. Desai
Keyword(s):  
Quality Of Life ◽  
Cross Sectional Study ◽  
Chronic Obstructive ◽  
Health Related Quality ◽  
Cross Sectional ◽  
Copd Patients ◽  
Related Quality ◽  
Health Related ◽  
Impaired Quality

Background: Chronic obstructive pulmonary disease (COPD) is a progressive lung disease that causes breathlessness (initially with exertion) and predisposes to exacerbations and serious illness. COPD is not curable, improvement of quality of life of such patients is thus of importance. The aims and objective of the study was to assess health related quality of life and its determinants in patients with COPD.Methods: Cases were first identified from the medical records of Department of RHTC, Mandur. Eligible cases were then interviewed by home visits. Health Related Quality of Life (HRQL) of participants was assessed using St. George’s Respiratory Questionnaire (SGRQ). ANOVA, student’s t test and correlation were used to interpret the data.Results: This study shows an impaired quality of life in COPD patients. Quality of life was impaired in all the domains. However, activity domain was the most affected while impact domain was least affected. Age, sex, smoking, BMI, socioeconomic status, occupation did not impact quality of life in significant manner.Conclusions: This study shows an impaired quality of life in COPD patients. As COPD is slowly progressing disease with no specific cure, we should focus more on treatable aspects of quality of life.

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