scholarly journals Biocompatible orthodontic cement with antibacterial capability and protein repellency

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Miao Chen ◽  
Jianru Yi ◽  
Zhihe Zhao

Abstract Background White spot lesions (WSLs) often occur in orthodontic treatments. The objectives of this study were to develop a novel orthodontic cement using particles of nano silver (NAg), N-acetylcysteine (NAC) and 2-methacryloyloxyethyl phosphorylcholine (MPC), and to investigate the effects on bonding strength, biofilms and biocompatibility. Methods A commercial resin-modified glass ionomer cement (RMGIC) was modified by adding NAg, NAC and MPC. The unmodified RMGIC served as the control. Enamel bond strength and cytotoxicity of the cements were investigated. The protein repellent behavior of cements was also evaluated. The metabolic assay, lactic acid production assay and colony-forming unit assay of biofilms were used to determine the antibacterial capability of cements. Results The new bioactive cement with NAg, NAC and MPC had clinically acceptable bond strength and biocompatibility. Compared to commercial control, the new cement suppressed metabolic activity and lactic acid production of biofilms by 59.03% and 70.02% respectively (p < 0.05), reduced biofilm CFU by 2 logs (p < 0.05) and reduced protein adsorption by 76.87% (p < 0.05). Conclusions The new cement with NAg, NAC and MPC had strong antibacterial capability, protein-repellent ability and acceptable biocompatibility. The new cement is promising to protect enamel from demineralization during orthodontic treatments.

1994 ◽  
Vol 21 (1) ◽  
pp. 23-26 ◽  
Author(s):  
A. Hallgren ◽  
A. Oliveby ◽  
S. Twetman

The lactic acid production in suspensions of plaque collected adjacent to orthodontic brackets retained with a glass ionomer cement (GIC), or a resin-based composite was investigated using a split-mouth technique. Forty-eight-hour-old plaque was collected at 3, 8, and 28 days, and 3 months after the onset of orthodontic treatment. Acid fermentation was induced by glucose and the L(+)-lactic acid concentrations were determined enzymatically after a 30-minute incubation period. Significantly (P<0·05) lower levels of lactic acid were found in plaque from GIC-retained brackets compared with the composite controls at the 28 days and 3 months sampling occasions, respectively. The results suggest that the use of GIC as a bonding agent in orthodontics can be beneficial for patients assessed at risk of caries development.


2020 ◽  
Vol 8 (02) ◽  
pp. 49-54
Author(s):  
Salil Mehra ◽  
Ashu K. Gupta ◽  
Bhanu Pratap Singh ◽  
Mandeep Kaur ◽  
Ashwath Kumar

Abstract Introduction The aim of the current study was to evaluate shear bond strength of resin composite bonded to Theracal LC, Biodentine, and resin-modified glass ionomer cement (RMGIC) using universal adhesive and mode of fracture. Materials and Methods A total of 50 caries-free maxillary and mandibular molars extracted were taken; occlusal cavities were prepared, mounted in acrylic blocks, and divided into five groups based on the liner used. Group 1: Biodentine liner placed into the cavity and bonding agent and resin composite applied after 12 minutes. Group 2: Biodentine liner placed into the cavity and bonding agent and resin composite applied after 14 days. Group 3: RMGIC liner placed into the cavity and bonding agent and resin composite applied immediately. Group 4: RMGIC liner placed into the cavity and bonding agent and resin composite applied after 7 days. Group 5: Theracal LC liner placed into the cavity and bonding agent and resin composite applied immediately. Each sample was bonded to resin composite using universal adhesive. Shear bond strength analysis was performed at a cross-head speed of 0.1 mm/min. Statistical Analysis  Statistical analysis was performed with one-way analysis of variance and posthoc Bonferroni test using SPSS version 22.0. Results and Conclusion Biodentine liner when bonded immediately to resin composite showed minimum shear bond strength. RMGIC when bonded to resin composite after 7 days showed maximum shear bond strength. Mode of fracture was predominantly cohesive in groups having Biodentine and Theracal LC as liner.


2010 ◽  
Vol 33 (2) ◽  
pp. 180-184 ◽  
Author(s):  
H. Y. Cheng ◽  
C. H. Chen ◽  
C. L. Li ◽  
H. H. Tsai ◽  
T. H. Chou ◽  
...  

2013 ◽  
Vol 38 (2) ◽  
pp. 186-196 ◽  
Author(s):  
Camila Sabatini ◽  
Manthan Patel ◽  
Eric D'Silva

SUMMARY Objective To evaluate the shear bond strength (SBS) of three self-adhesive resin cements and a resin-modified glass ionomer cement (RMGIC) to different prosthodontic substrates. Materials and Methods The substrates base metal, noble metal, zirconia, ceramic, and resin composite were used for bonding with different cements (n=12). Specimens were placed in a bonding jig, which was filled with one of four cements (RelyX Unicem, Multilink Automix, Maxcem Elite, and FujiCEM Automix). Both light-polymerizing (LP) and self-polymerizing (SP) setting reactions were tested. Shear bond strength was measured at 15 minutes and 24 hours in a testing device at a test speed of 1 mm/min and expressed in MPa. A Student t-test and a one-way analysis of variance (ANOVA) were used to evaluate differences between setting reactions, between testing times, and among cements irrespective of other factors. Generalized linear regression model and Tukey tests were used for multifactorial analysis. Results Significantly higher mean SBS were demonstrated for LP mode relative to SP mode (p&lt;0.001) and for 24 hours relative to 15 minutes (p&lt;0.001). Multifactorial analysis revealed that all factors (cement, substrate, and setting reaction) and all their interactions had a significant effect on the bond strength (p&lt;0.001). Resin showed significantly higher SBS than other substrates when bonded to RelyX Unicem and Multilink Automix in LP mode (p&lt;0.05). Overall, FujiCEM demonstrated significantly lower SBS than the three self-adhesive resin cements (p&lt;0.05). Conclusions Overall, higher bond strengths were demonstrated for LP relative to SP mode, 24 hours relative to 15 minutes and self-adhesive resin cements compared to the RMGICs. Bond strengths also varied depending on the substrate, indicating that selection of luting cement should be partially dictated by the substrate and the setting reaction.


2018 ◽  
Vol 29 (2) ◽  
pp. 128-132 ◽  
Author(s):  
Gabriela Cristina Santin ◽  
Alexandra Mussolino de Queiroz ◽  
Regina Guenka Palma-Dibb ◽  
Harley Francisco de Oliveira ◽  
Paulo Nelson Filho ◽  
...  

Abstract Patients undergoing radiotherapy treatment present more susceptibility to dental caries and the use of an orthodontic device increases this risk factor due to biofilm accumulation around the brackets. The objective of this study was to evaluate the shear bond strength to irradiated permanent teeth of orthodontic brackets bonded with conventional glass ionomer cement and resin-modified glass ionomer cement due to the fluoride release capacity of these materials. Ninety prepared human premolars were divided into 6 groups (n=15), according to the bonding material and use or not of radiation: CR: Transbond XT composite resin; RMGIC: Fuji Ortho LC conventional glass ionomer cement; GIC: Ketac Cem Easymix resin-modified glass ionomer cement. The groups were irradiated (I) or non-irradiated (NI) prior to bracket bonding. The specimens were subjected to a fractioned radiation dose of 2 Gy over 5 consecutive days for 6 weeks. After the radiotherapy, the brackets were bonded on the specimens with Transbond XT, Fuji Ortho LC and Ketac Cem Easymix. After 24 h, the specimens were subjected to shear bond strength test. The image of enamel surface (classified by Adhesive Remnant Index - ARI) was also evaluated and its frequency was checked among groups/subgroups. The shear bond strength variable was evaluated with ANOVA and Tukey’s post-hoc test. GIC group showed the lowest adhesion values among the groups (p<0.05). There was no statistically significant difference among non-irradiated and irradiated groups (p>0.05). As for the ARI, the CR-I group showed the highest material retention on enamel surface among the irradiated groups. RMGIC group showed the highest values for shear bond strength and presented ARI acceptable for clinical practices.


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