scholarly journals Leaf extract of Caesalpinia mimosoides enhances oxidative stress resistance and prolongs lifespan in Caenorhabditis elegans

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Panthakarn Rangsinth ◽  
Anchalee Prasansuklab ◽  
Chatrawee Duangjan ◽  
Xiaojie Gu ◽  
Krai Meemon ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Caenorhabditis Elegans ◽  
Stress Resistance ◽  
Leaf Extract ◽  
Oxidative Stress Resistance

scholarly journals Production of YP170 Vitellogenins Promotes Intestinal Senescence in Caenorhabditis elegans

2019 ◽  
Vol 74 (8) ◽  
pp. 1180-1188 ◽  
Author(s):  
Thanet Sornda ◽  
Marina Ezcurra ◽  
Carina Kern ◽  
Evgeniy R Galimov ◽  
Catherine Au ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Caenorhabditis Elegans ◽  
Life Span ◽  
Stress Resistance ◽  
Later Life ◽  
Abundant Species ◽  
Yolk Proteins ◽  
Oxidative Stress Resistance ◽  
Vitellogenin Synthesis ◽  
Intestinal Atrophy

Abstract During aging, etiologies of senescence cause multiple pathologies, leading to morbidity and death. To understand aging requires identification of these etiologies. For example, Caenorhabditis elegans hermaphrodites consume their own intestinal biomass to support yolk production, which in later life drives intestinal atrophy and ectopic yolk deposition. Yolk proteins (YPs; vitellogenins) exist as three abundant species: YP170, derived from vit-1–vit-5; and YP115 and YP88, derived from vit-6. Here, we show that inhibiting YP170 synthesis leads to a reciprocal increase in YP115/YP88 levels and vice versa, an effect involving posttranscriptional mechanisms. Inhibiting YP170 production alone, despite increasing YP115/YP88 synthesis, reduces intestinal atrophy as much as inhibition of all YP synthesis, which increases life span. By contrast, inhibiting YP115/YP88 production alone accelerates intestinal atrophy and reduces life span, an effect that is dependent on increased YP170 production. Thus, despite copious abundance of both YP170 and YP115/YP88, only YP170 production is coupled to intestinal atrophy and shortened life span. In addition, increasing levels of YP115/YP88 but not of YP170 increases resistance to oxidative stress; thus, longevity resulting from reduced vitellogenin synthesis is not attributable to oxidative stress resistance.

scholarly journals Monascus-Fermented Dioscorea Enhances Oxidative Stress Resistance via DAF-16/FOXO in Caenorhabditis elegans

PLoS ONE ◽  
2012 ◽  
Vol 7 (6) ◽  
pp. e39515 ◽  
Author(s):  
Yeu-Ching Shi ◽  
Chan-Wei Yu ◽  
Vivian Hsiu-Chuan Liao ◽  
Tzu-Ming Pan
Keyword(s):  
Oxidative Stress ◽  
Caenorhabditis Elegans ◽  
Stress Resistance ◽  
Oxidative Stress Resistance

scholarly journals Correction: A Novel Role for the SMG-1 Kinase in Lifespan and Oxidative Stress Resistance in Caenorhabditis elegans

PLoS ONE ◽  
2009 ◽  
Vol 4 (1) ◽  
Author(s):  
Ingrid Masse ◽  
Laurent Molin ◽  
Laurent Mouchiroud ◽  
Philippe Vanhems ◽  
Francesca Palladino ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Caenorhabditis Elegans ◽  
Stress Resistance ◽  
Oxidative Stress Resistance ◽  
And Oxidative Stress

scholarly journals Arginine methylation of SKN-1 promotes oxidative stress resistance in Caenorhabditis elegans

Redox Biology ◽  
2019 ◽  
Vol 21 ◽  
pp. 101111 ◽  
Author(s):  
Hongyuan Li ◽  
Liangping Su ◽  
Xin Su ◽  
Xin Liu ◽  
Dan Wang ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Caenorhabditis Elegans ◽  
Stress Resistance ◽  
Arginine Methylation ◽  
Oxidative Stress Resistance

scholarly journals Açaí (Euterpe oleracea Mart.) Modulates Oxidative Stress Resistance in Caenorhabditis elegans by Direct and Indirect Mechanisms

PLoS ONE ◽  
2014 ◽  
Vol 9 (3) ◽  
pp. e89933 ◽  
Author(s):  
Larissa de Freitas Bonomo ◽  
David Nunes Silva ◽  
Patrícia Ferreira Boasquivis ◽  
Franciny Aparecida Paiva ◽  
Joyce Ferreira da Costa Guerra ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Caenorhabditis Elegans ◽  
Stress Resistance ◽  
Euterpe Oleracea ◽  
Oxidative Stress Resistance ◽  
Euterpe Oleracea Mart

scholarly journals A Novel Role for the SMG-1 Kinase in Lifespan and Oxidative Stress Resistance in Caenorhabditis elegans

PLoS ONE ◽  
2008 ◽  
Vol 3 (10) ◽  
pp. e3354 ◽  
Author(s):  
Ingrid Masse ◽  
Laurent Molin ◽  
Laurent Mouchiroud ◽  
Philippe Vanhems ◽  
Francesca Palladino ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Caenorhabditis Elegans ◽  
Stress Resistance ◽  
Oxidative Stress Resistance ◽  
And Oxidative Stress
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