scholarly journals Clinical pharmacist assessment of drug-related problems among intensive care unit patients in a Turkish university hospital

2022 ◽  
Vol 22 (1) ◽  
Author(s):  
Aslınur Albayrak ◽  
Bilgen Başgut ◽  
Gülbin Aygencel Bıkmaz ◽  
Bensu Karahalil

Abstract Background Critically ill patients treated in the intensive care units (ICUs) often suffer from side effects and drug-related problems (DRPs) that can be life-threatening. A way to prevent DRPs and improve drug safety and efficacy is to include clinical pharmacists in the clinical team. This study aims to evaluate the classification of drug-related problems and the implementation of clinical pharmacy services by a clinical pharmacist in the ICU of a university hospital in Turkey. Methods This study was carried out prospectively between December 2020 and July 2021 in Gazi University Medical Faculty Hospital Internal Diseases ICU. All patients hospitalized in the intensive care unit for more than 24 h were included in the study. During the study, the clinical pharmacist's interventions and other clinical services for patients were recorded. DRPs were classed according to the Pharmaceutical Care Network Europe V.8.02. Results A total of 151 patients were included during the study period corresponding to 2264 patient-days. Patients with DRPs had a longer hospital stay and a higher mortality rate (p < 0.05). 108 patients had at least one DRP and the total number of DRPs was 206. There was an average of 1.36 DRPs per patient, 71.5% of patients experienced DRP and 89.22 DRPs per 1000 patient-days. A total of 35 ADEs were observed in 32 patients. ADE incidence was per 1000 patient-days 15.45. ADEs were caused by nephrotoxicity (48.57%), electrolyte disorders (17.14%), drug-induced thrombocytopenia (17.14%), liver enzyme increase (8.57%) and other causes (8.57%). Drug selection (40.29%) and dose selection (54.36%) constituted most of the causes of DRPs. Dose change was the highest percentage of planned interventions with a rate of 56.79%. Intervention was accepted at a rate of 90.8% and it was fully implemented. Conclusion In this study, the importance of the clinical pharmacist in the determination and analysis of DRPs was emphasized. Clinical pharmacy services like the one described should be implemented widely to increase patient safety.

2018 ◽  
Vol 25 (6) ◽  
pp. 1312-1320 ◽  
Author(s):  
Ahmet S Boşnak ◽  
Nevzat Birand ◽  
Ömer Diker ◽  
Abdikarim Abdi ◽  
Bilgen Başgut

Background Clinical pharmacists have important roles in implementing scientifically valid knowledge and advice on safe, reasonable use of pharmaceuticals. Clinical pharmacy services were introduced and evaluated in oncology clinic in a tertiary university hospital. Methods A prospective interventional study was conducted from November 2017 to March 2018. Drug-related problems were classified using the Pharmaceutical Care Network Europe drug-related problem classification tool v8.01. The main outcome measure is the proposed interventions aimed at identification of the drug-related problems, the role of the pharmacists in the resolution, and the rate of acceptance of these recommendations by physicians. Results A total of 102 patients were included in the study, who were treated with at least two cycles of any cancer type and stage. A total of 55 (53.9%) patients had 251 drug-related problems. Drug-related problems mainly involved antihypertensive (31.6%), antidiabetic (17.8%), and herbal agents (31.6%). Treatment effectiveness was the major type of drug-related problems (50.2%) followed by treatment safety (29.1%). A total of 211 (100%) interventions were accepted and regarded as clinically relevant. Prescriber informed only were the most common types of intervention at the prescriber level. Eighty-six point four percent identified drug-related problems were solved, 9.8% of the problems were partially solved, 2.3% problems were unsolved. Conclusion Clinical pharmacy services may have optimized therapy effectiveness, prevent adverse effects and unclear/compliant problems. The pharmacist interventions were highly acknowledged by oncologists and patients; this may indicate the presence of a great convenience and need to implement Clinical pharmacy services in alternative hospitals in Northern Cyprus.


2002 ◽  
Vol 59 (19) ◽  
pp. 1888-1889 ◽  
Author(s):  
Zaidi Syed Tabish Razi ◽  
Sheikh Abdul Latif ◽  
Raza Syed Shamim

SpringerPlus ◽  
2014 ◽  
Vol 3 (1) ◽  
pp. 34 ◽  
Author(s):  
Jeong Kim ◽  
So Park ◽  
You Sohn ◽  
Young Lee ◽  
Catherine Yang ◽  
...  

2020 ◽  
Vol 11 (SPL4) ◽  
pp. 745-750
Author(s):  
Bushan Kumar GG ◽  
Jyothi Singamsetty ◽  
Rajasekhar K V ◽  
Sahitya Meda

Clinical pharmacy services are the services provided by the pharmacists to promote patient care, optimizes medication therapy, promote health and disease prevention. This prospective cross sectional study was conducted in tertiary care hospital over a period of 6 months. This collected data is checked for their appropriateness of any prescription related errors and DRPs were identified. Results obtained were assessed to determine the influence of Clinical pharmacist services. Majority of the prescriptions were with 5-9(62.5%) drugs. The majority of co-morbidities among 125 enrolled patients in age group of 60-70, 55 patients were with 3-4 co-morbidities. Among 125 prescriptions around 12 prescriptions were identified with 622 drug interactions. Among 125 patients 2 (0.277) adverse drug reactions were observed and according to Naranjo's probability assessment scale these adverse drug reactions were mild and 15(2.08%) dispensing errors, 10(1.386%) prescription errors where majority of prescription errors are due to missed written frequencies in the prescriptions. 5(0.693%) administration errors, 5 (0.693%)untreated indications were observed. Presence of clinical pharmacist in hospital settings can reduce drug related problems and they can assist other staff in improving patient care.


1987 ◽  
Vol 21 (9) ◽  
pp. 748-751 ◽  
Author(s):  
Ene I. Ette ◽  
Judy I. Achumba ◽  
Esther A. Brown-Awala

The types and frequency of questions asked of clinical pharmacists introducing clinical pharmacy services in the internal medicine wards of a Nigerian university hospital and the degree of compliance with pharmacists' recommendations were studied. Three faculty pharmacists collected data in two 30-working day study periods, separated by a year. Totals of 197 questions (an average of 6.57 ± 1.33 questions/working day) and 271 questions (an average of 9.03 ± 1.10 questions/working day) were answered by the pharmacists in the first and second study periods, respectively. Pharmacists recommended changes in patient-specific drug therapy that were implemented 52 percent and 69 percent of the time in the first and second study periods, respectively. The most common type of drug information request concerned the presence or the likelihood of an adverse drug reaction. Continuous interaction between pharmacists and physicians in the patient-care setting results in a better appreciation of the pharmacist's role as drug information consultant, and the consequence of this is a high degree of compliance with pharmacists' recommendations.


2017 ◽  
Vol 39 (6) ◽  
pp. 1185-1193 ◽  
Author(s):  
Haider Al-Baghdadi ◽  
Çiğdem Koca Al-Baghdadi ◽  
Abdikarim Abdi ◽  
Onur Gültekin ◽  
Arijana Meštrović ◽  
...  

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