scholarly journals Unrecognized circulation of SAT 1 foot-and-mouth disease virus in cattle herds around Queen Elizabeth National Park in Uganda

2016 ◽  
Vol 12 (1) ◽  
Author(s):  
Moses Tefula Dhikusooka ◽  
Chrisostom Ayebazibwe ◽  
Alice Namatovu ◽  
Graham J. Belsham ◽  
Hans Redlef Siegismund ◽  
...  
2006 ◽  
Vol 159 (10) ◽  
pp. 299-308 ◽  
Author(s):  
B. M. de C. Bronsvoort ◽  
J. Anderson ◽  
A. Corteyn ◽  
P. Hamblin ◽  
R. P. Kitching ◽  
...  

1965 ◽  
Vol 63 (3) ◽  
pp. 357-368 ◽  
Author(s):  
N. St G. Hyslop ◽  
R. H. Fagg

Foot-and-mouth disease virus of Type SAT 1 (strain Turkey 323/62) was passaged serially 34 times in cattle previously vaccinated with increasing doses of formol-treated vaccine of the homologous strain. Primary vesicles developed in all the partly immunized animals and secondary lesions occurred in the majority. Virus from the 34th passage was capable of reinfecting a steer only 76 days after primary infection early in the passage series. Virus isolated from the second infection of this animal differed from that isolated from the primary infection in complement-fixing properties and in sensitivity to antiserum, and these differences were of a degree indicative of subtype variation.The variant strain was transmissible by contact, and virus titres in tongue and foot lesions of partly immunized animals were of the same order as those encountered in susceptible cattle.These observations suggest one way in which variant strains may arise in the field.


2010 ◽  
Vol 58 (2) ◽  
pp. 173-178 ◽  
Author(s):  
W. Vosloo ◽  
S. P. Swanepoel ◽  
M. Bauman ◽  
B. Botha ◽  
J. J. Esterhuysen ◽  
...  

2020 ◽  
Vol 176 ◽  
pp. 104929 ◽  
Author(s):  
Daniel Nthiwa ◽  
Bernard Bett ◽  
David Odongo ◽  
Eucharia Kenya ◽  
Martin Wainaina ◽  
...  

Author(s):  
Christopher J. Kasanga ◽  
Raphael Sallu ◽  
Fredrick Kivaria ◽  
Mathias Mkama ◽  
Joseph Masambu ◽  
...  

This study was conducted to investigate the presence of foot-and-mouth disease virus (FMDV) in different geographic locations of Tanzania. Epithelial tissues and fluids (n = 364) were collected from cattle exhibiting oral and foot vesicular lesions suggestive of FMD and submitted for routine FMD diagnosis. The analysis of these samples collected during the period of 2002 and 2010 was performed by serotype-specific antigen capture ELISA to determine the presence of FMDV. The results of this study indicated that 167 out of 364 (46.1%) of the samples contained FMDV antigen. Of the 167 positive samples, 37 (28.4%) were type O, 7 (4.1%) type A, 45 (21.9%) SAT 1 and 79 (45.6%) SAT 2. Two FMDV serotypes (O and SAT 2) were widely distributed throughout Tanzania whilst SAT 1 and A types were only found in the Eastern zone. Our findings suggest that serotypes A, O, SAT 1 and SAT 2 prevail in Tanzania and are associated with the recent FMD outbreaks. The lack of comprehensive animal movement records and inconsistent vaccination programmes make it difficult to determine the exact source of FMD outbreaks or to trace the transmission of the disease over time. Therefore, further collection and analysis of samples from domestic and wild animals are being undertaken to investigate the genetic and antigenic characteristics of the circulating strains, so that a rational method to control FMD in Tanzania and the neighbouring countries can be recommended.


1963 ◽  
Vol 61 (2) ◽  
pp. 217-230 ◽  
Author(s):  
N. St G. Hyslop ◽  
J. Davie ◽  
Sally P. Carter

Antigenic differences between the strains RV 11 and SA 13/61 of foot-and-mouth disease virus (type SAT 1) were studiedin vivoby cross-protection tests. Cattle inoculated with formolized antigen of either strain developed good immunity to experimental infection with the identical strain but little resistance to the other strain.In vitrothe results of complement fixation tests and of serum-virus neutralization tests in tissue culture were consistent with the observations madein vivo. The results of studies on the serological relationships between four strains of type SAT 1 are presented.The importance of strain differences in the epizootiology and control of the disease is discussed briefly.The authors wish to thank Dr I. A. Galloway and Dr J. B. Brooksby for their advice and criticism, and to acknowledge the valuable technical assistance of Mr K. Herniman, Mr R. L. G. King and Mr E. Scoates.


2019 ◽  
Vol 8 (49) ◽  
Author(s):  
Miranda R. Bertram ◽  
Simon Dickmu ◽  
Rachel M. Palinski ◽  
Steven J. Pauszek ◽  
Ethan J. Hartwig ◽  
...  

We report the genomes of four foot-and-mouth disease virus (FMDV) serotype SAT 1 topotype X isolates from Cameroon. The viruses were isolated from bovine epithelium collected during an outbreak in 2016. These novel sequences update knowledge of FMDV diversity in Central Africa and contribute to regional FMDV molecular epidemiology.


1975 ◽  
Vol 74 (2) ◽  
pp. 227-232 ◽  
Author(s):  
A. J. Forman

SUMMARYSixteen foot-and-mouth disease virus (FMDV) strains of type SAT 1 were compared in complement-fixation tests. With the test used, the range of antigenic variation within a type appeared to be greater than previously described. The concept of a sub-type group within which all strains are more closely related to each other than to any strain outside the group was not supported. Considering the group of strains studied, it is suggested that the classification of strains is best achieved by nominating a reference strain for each sub-type. Others are classified as related strains in one or more sub-type groups according to their relationships with the reference strains.


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