Molecular characterization of a novel Muscovy duck parvovirus isolate: evidence of recombination between classical MDPV and goose parvovirus strains

ABSTRACT: Goose parvovirus (GPV), also called Derzsy’s disease, is a viral pathogen that causes high morbidity and mortality in goslings and ducklings. In this study, we perform the molecular characterization of the GPV in Turkey. The definition of similarity to the world of GPV isolates in Turkey and construction of a phylogenetic tree was aimed. For this purpose, the presence of GPV in the liver, spleen, and intestine tissues of nine goslings with symptoms such as dysphagia, bilateral ocular swelling, eye discharge, diarrhea, and fatigue were investigated by real-time PCR method and all samples were detected as positive. According to the data obtained by molecular characterization, phylogenetic analysis of GPV has been presented in Turkey. As a result of this study, it was determined that the GPVs available in Turkey are virulent strains.

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Identification of recombination between Muscovy duck parvovirus and goose parvovirus structural protein genes

Archives of Virology ◽

10.1007/s00705-015-2541-9 ◽

2015 ◽

Vol 160 (10) ◽

pp. 2617-2621 ◽

Cited By ~ 13

Author(s):

Hongxing Shen ◽

Wen Zhang ◽

Hua Wang ◽

Yang Zhou ◽

Shihe Shao

Keyword(s):

Muscovy Duck ◽

Structural Protein ◽

Goose Parvovirus ◽

Muscovy Duck Parvovirus

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Biochemical and genomic characterization of muscovy duck parvovirus

Archives of Virology ◽

10.1007/bf01309459 ◽

1994 ◽

Vol 139 (1-2) ◽

pp. 121-131 ◽

Cited By ~ 48

Author(s):

G. Le Gall-Reculé ◽

V. Jestin

Keyword(s):

Muscovy Duck ◽

Genomic Characterization ◽

Muscovy Duck Parvovirus

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Molecular Characterization and Pathogenicity of the Novel Recombinant Muscovy Duck Parvovirus Isolated from Geese

Animals ◽

10.3390/ani11113211 ◽

2021 ◽

Vol 11 (11) ◽

pp. 3211

Author(s):

Kuang-Po Li ◽

Yu-Chen Hsu ◽

Chih-An Lin ◽

Poa-Chun Chang ◽

Jui-Hung Shien ◽

...

Keyword(s):

Genomic Sequence ◽

Economic Losses ◽

High Morbidity ◽

Post Inoculation ◽

Muscovy Duck ◽

The Novel ◽

Highly Pathogenic ◽

Goose Parvovirus ◽

Challenge Tests ◽

Muscovy Duck Parvovirus

Goose parvovirus (GPV) and Muscovy duck parvovirus (MDPV) are the main agents associated with waterfowl parvovirus infections that caused great economic losses in the waterfowl industry. In 2020, a recombinant waterfowl parvovirus, 20-0910G, was isolated in a goose flock in Taiwan that experienced high morbidity and mortality. The whole genome of 20-0910G was sequenced to investigate the genomic characteristics of this isolate. Recombination analysis revealed that, like Chinese rMDPVs, 20-0910G had a classical MDPV genomic backbone and underwent two recombination events with classical GPVs at the P9 promoter and partial VP3 gene regions. Phylogenetic analysis of the genomic sequence found that this goose-origin parvovirus was highly similar to the circulating recombinant MDPVs (rMDPVs) isolated from duck flocks in China. The results of experimental challenge tests showed that 20-0910G caused 100% mortality in goose embryos and in 1-day-old goslings by 11 and 12 days post-inoculation, respectively. Taken together, the results indicated that this goose-origin rMDPV was closely related to the duck-origin rMDPVs and was highly pathogenic to young geese.

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Advances in research on genetic relationships of waterfowl parvoviruses

Journal of Veterinary Research ◽

10.2478/jvetres-2021-0063 ◽

2021 ◽

Vol 0 (0) ◽

Author(s):

Yanhui Chen ◽

Ruth Afumba ◽

Fusheng Pang ◽

Rongxin Yuan ◽

Hao Dong

Keyword(s):

Clinical Symptoms ◽

Genetic Relationships ◽

Eastern China ◽

Economic Losses ◽

Muscovy Duck ◽

Mortality And Morbidity ◽

Causative Agents ◽

Goose Parvovirus ◽

Short Beak ◽

Muscovy Duck Parvovirus

Abstract Derzsy’s disease and Muscovy duck parvovirus disease have become common diseases in waterfowl culture in the world and their potential to cause harm has risen. The causative agents are goose parvovirus (GPV) and Muscovy duck parvovirus (MDPV), which can provoke similar clinical symptoms and high mortality and morbidity rates. In recent years, duck short beak and dwarfism syndrome has been prevalent in the Cherry Valley duck population in eastern China. It is characterised by the physical signs for which it is named. Although the mortality rate is low, it causes stunting and weight loss, which have caused serious economic losses to the waterfowl industry. The virus that causes this disease was named novel goose parvovirus (NGPV). This article summarises the latest research on the genetic relationships of the three parvoviruses, and reviews the aetiology, epidemiology, and necropsy characteristics in infected ducks, in order to facilitate further study.

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Genetic characterization and phylogenetic analysis of Novel Duck-Origin Goose Parvovirus in Anhui Province, Eastern China

10.21203/rs.3.rs-202531/v1 ◽

2021 ◽

Author(s):

Yong Wang ◽

Jianfei Sun ◽

Da Zhang ◽

Xu Guo ◽

Wenhao Shen ◽

...

Keyword(s):

Phylogenetic Analysis ◽

Genome Sequencing ◽

Phylogenetic Trees ◽

Genetic Characterization ◽

Eastern China ◽

Anhui Province ◽

Muscovy Duck ◽

Goose Parvovirus ◽

Short Beak ◽

Muscovy Duck Parvovirus

Abstract Recently, a novel duck-origin goose parvovirus (N-GPV) was reported to cause short beak and dwarfism syndrome in ducks. In this study, we performed complete genome sequencing and analyzed three different duck-derived parvoviruses that infected different breeds of ducks. Phylogenetic trees based on gene sequences indicated that they were classical goose parvovirus (C-GPV), Muscovy duck parvovirus (MDPV), and N-GPV, respectively. Furthermore, potential recombination events were found. These results improve our understanding of the diversity of duck-derived parvoviruses in the Anhui province, eastern China, and provide a reference for the prevention of associated diseases.

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