scholarly journals Effects of omega-3 carboxylic acids on lipoprotein particles and other cardiovascular risk markers in high-risk statin-treated patients with residual hypertriglyceridemia: a randomized, controlled, double-blind trial

2015 ◽  
Vol 14 (1) ◽  
Author(s):  
Richard L. Dunbar ◽  
Stephen J. Nicholls ◽  
Kevin C. Maki ◽  
Eli M. Roth ◽  
David G. Orloff ◽  
...  
2009 ◽  
Vol 201 (6) ◽  
pp. S127-S128 ◽  
Author(s):  
Avi Harlev ◽  
Barak Aricha-Tamir ◽  
Roy Kessous ◽  
Savyona Ben Ayun ◽  
Arnon Wiznitzer ◽  
...  

2016 ◽  
Vol 194 ◽  
pp. 774-780 ◽  
Author(s):  
Yong-jun Ahn ◽  
Joon-Shik Shin ◽  
Jinho Lee ◽  
Yoon Jae Lee ◽  
Me-riong Kim ◽  
...  

2001 ◽  
Vol 18 (6) ◽  
pp. 389-393 ◽  
Author(s):  
U. R. Döpfmer ◽  
M. R. Schenk ◽  
S. Kuscic ◽  
D. H. Beck ◽  
S. Döpfmer ◽  
...  

Author(s):  
N Ciavarella ◽  
S Antoneecchit ◽  
N D’Elia ◽  
P Ranieri ◽  
A Manzini

Platelets play an important role in thromboembo lie episodes in the life of patients with heart prosthetic valves. Decreased platelet survival and increased B-Tromboglobulin and Platelet F4 in the blood are constant features of such condition.45 patients on long term anticoagulant treatment (thrombotest 5-10%),26 males(mean age 46) and 19 females(mean age 44), were studied. 22 normal sub jects served as controls.Platelets survival was studied with MDA production after 5oo mg Aspirin intake and was found signifi canly reduced in patients in comparison to contro Is(p.8.00±1.4 days;c.10.00±1.67 days; P<0.01).BTG and PF4 as measured by RIA were increased (BTG:p.97.8±59 NG/ML;c.29.18±22.40 NG/ML; P<0.01) (PF4:p.36.6±26.5 NG/ML;c.6.29±4.78 NG/ML; P<0.01) The patients were randomly allocated to one of the following groups( 15 subjects each): placebo, Suloctidil 600 mg:die, Suloctidil 1200 mg:die. Duration treatment was 30 days.The effect of Suloctidil was significantly different from that of placebo( P<0.005),as regards Platelet survival without difference between dosa ges of the drug;as concerns BTG and PF4 the chang es under placebo and drug were not different.


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