scholarly journals Hepatitis C and HIV incidence and harm reduction program use in a conflict setting: an observational cohort of injecting drug users in Kabul, Afghanistan

2015 ◽  
Vol 12 (1) ◽  
Author(s):  
Catherine S. Todd ◽  
Abdul Nasir ◽  
Mohammad Raza Stanekzai ◽  
Katja Fiekert ◽  
Heather L. Sipsma ◽  
...  
Addiction ◽  
2013 ◽  
Vol 108 (6) ◽  
pp. 1070-1081 ◽  
Author(s):  
Anneke S. de Vos ◽  
Jannie J. van der Helm ◽  
Amy Matser ◽  
Maria Prins ◽  
Mirjam E. E. Kretzschmar

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Abdolhalim Rajabi ◽  
Heidar Sharafi ◽  
Seyed Moayed Alavian

Abstract Background Prevalence of hepatitis C virus (HCV) infection among people who inject drugs (PWID) in Iran is high. Since 2005, the Iranian government has implemented a harm reduction program to control HCV. We aimed to describe the prevalence of HCV antibody (Ab) in Iranian PWID before and after the implementation of harm reduction with cumulative meta-analysis. Methods Following PRISMA guidelines, we conducted a systematic review and meta-analysis of studies published on the seroprevalence of HCV among PWID. We systematically reviewed the literature to identify eligible studies up to December 2018 in international and national databases. Pooled prevalence and 95% confidence intervals were calculated using Der Simonian and Laird method, taking into account conceptual heterogeneity. Subgroup analyses were performed by harm reduction implementation and studies’ characteristics to assess the sources of heterogeneity. We used Cochran–Armitage test for the linear trend of the prevalence of HCV Ab among PWID. Results We reviewed 5966 papers and reports and extracted data from 62 eligible records. The pooled HCV Ab prevalence among PWID in Iran was 46.5% (95% confidence interval [95% CI] 41.1–52.0%). Overall, the Cochran–Armitage test for trend indicated a significant decreasing trend of HCV Ab prevalence (P = 0.04). The cumulative meta-analysis showed a slight decline in the prevalence of HCV Ab between the years 2005 and 2018. Conclusions The HCV Ab prevalence among PWID in Iran is high, with a considerable geographical variation. The prevalence of HCV Ab among PWID in Iran slightly decreased after 2005 which could be, at least to some extent, related to the implementation of extensive harm reduction programs in the country.


Addiction ◽  
2011 ◽  
Vol 106 (8) ◽  
pp. 1437-1445 ◽  
Author(s):  
Yen-Fang Huang ◽  
Hsu-Sung Kuo ◽  
Chin-Yin Lew-Ting ◽  
Fang Tian ◽  
Chin-Hui Yang ◽  
...  

2006 ◽  
Vol 19 (5) ◽  
pp. 280-281 ◽  
Author(s):  
Zaheer-Ud-Din Babar ◽  
Nur Rashidah Mohd Zaini ◽  
Choon Wai Yee

In Malaysia, because of an alarming increase in the number of intravenous drug users, the government has started a harm reduction program in which methadone is used as a drug substitution therapy. This article discusses a 19-month-old Malay girl who was brought to the hospital after an episode of accidental ingestion of methadone. The methadone was for her uncle, who was found to be an intravenous drug user. Although methadone has been proven to be cost-effective and useful, it has also been reported that increasing availability of methadone can put children at increased risk of accidental ingestion. In Malaysia, methadone is available at government as well as private medical clinics. Home consumption may be problematic as the drug may be dispensed without adequate patient education and clear instructions on its handling, storage, and indication of use. In this scenario, a greater emphasis on and the adaptation of clear guidelines on the use and storage of methadone are required. There is also a need to create awareness among the public as well as health care professionals regarding the issue.


2004 ◽  
Vol 8 (16) ◽  
Author(s):  
A Taylor ◽  
A Fleming ◽  
Jeanne Rutherford ◽  
D Goldberg

There is considerable evidence that needle/syringe exchange provision has helped to control HIV transmission among injecting drug users (IDUs) [1]. However, the indications are that current interventions may be reducing, but are not controlling, the spread of hepatitis C infection (HCV) [2].


PLoS Medicine ◽  
2014 ◽  
Vol 11 (4) ◽  
pp. e1001625 ◽  
Author(s):  
Yen-Fang Huang ◽  
Jyh-Yuan Yang ◽  
Kenrad E. Nelson ◽  
Hsu-Sung Kuo ◽  
Chin-Yin Lew-Ting ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document