scholarly journals Pre-colectomy location and TNM staging of colon cancer by the computed tomography colonography: a diagnostic performance study

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Yadong Zhou ◽  
Zhiwei Han ◽  
Fafu Dou ◽  
Tao Yan
Keyword(s):  
Computed Tomography ◽  
Colon Cancer ◽  
Diagnostic Performance ◽  
Tnm Staging ◽  
Chinese Society ◽  
Level Of Evidence ◽  
Colon Wall ◽  
Colon Tumors ◽  
Computed Tomography Colonography ◽  
Differentiation Of Tumors

Abstract Background The Chinese Society of Clinical Oncology guidelines 2018 and the recent update of that (version 2020) recommends accurate examination before major treatment for decision(s) in cases of colon cancer. Also, the difficulty in the identification of the lesion during colectomy may lead to resection of a wrong segment of the colon or a more extensive resection than planned. Accurate pre-colectomy local staging of colon cancer is required to make decisions for treatment of colon cancer. The objective of the study was to evaluate the diagnostic performance of the computed tomography colonography (CTC) for pre-colectomy tumor location and tumor, node, and metastasis (TNM) staging of colon cancer. Methods Data of preoperative colonoscopies, CTC, surgeries, and surgical pathology of a total of 269 patients diagnosed with colon cancer by colonoscopy and biopsy and underwent pre-colectomy location and TNM staging by CTC were collected and analyzed. The consistency between the radiological and the surgery/surgical-pathological for location and TN stages of colon tumor were estimated with the weighted kappa or kappa coefficient (κ) at 95% confidence interval (CI). Results CTC detected 261 (93%) and colonoscopy detected 201 (72%) correct locations of tumors. Sensitivity and accuracy of CTC for detection of location of colon tumors were 100% and 92.58% (κ = 0.89; 95% Cl: 0.83–0.95). 72.48% sensitivity, 90.64% specificity, and 83.57% accuracy were reported for CTC in differentiation of tumors confined to the colon wall (T1/T2) from advanced tumors (T3/T4) (κ = 0.69, 95% Cl: 0.51–0.75). 81.01% sensitivity, 89.11% specificity, and 83.93% accuracy of CTC was reported for differentiation of tumors between low–intermediate risk and high risk (κ = 0.68, 95% Cl: 0.53–0.75). 69.31% sensitivity, 66.15% specificity, and 67.14% accuracy of CTC were reported for N staging of tumors (κ = 0.41, 95% Cl: 0.59–0.69). Conclusions CTC has high diagnostic parameters for pre-colectomy location and T staging of colon tumors except patients of colon cancer who received neoadjuvant chemotherapy. Level of Evidence III. Technical Efficacy Stage 2.

Incidental Extra-Colonic Findings in CT Colonography at Riyadh Region (Preprint)

2020 ◽  
Author(s):  
Muhannad Alanazi
Keyword(s):  
Computed Tomography ◽  
Colon Cancer ◽  
Medical Records ◽  
Medical Attention ◽  
Mortality And Morbidity ◽  
Computed Tomography Colonography ◽  
Screening Population ◽  
Extracolonic Findings ◽  
Atherosclerotic Changes

BACKGROUND Computed tomography colonography (CTC) is a new radiologic technique for examination of the colorectum. The search for, analysis and interpretation of extracolonic findings (ECFs) are a matter of permanent debate and review, given the arguments for and against them. OBJECTIVE To assess the prevalence and type of extracolonic findings (ECFs) in a screening population undergoing computed tomography colonography (CTC) in Riyadh region. METHODS This retrospective study was conducted in Riyadh region. To achieve the objectives of this study 305 subjects medical records were reviewed, where male represented 55% of participants and female represented only 45%. RESULTS About 21% of subjects had any type Extra Colonic Findings (ECFs) where about 74 incidental findings were identified in 65 patients. Out of these findings; 6 patients (9%) required immediate medical attention or urgent imaging/intervention, these included high suspicious of extracolonic malignancy or active infection, 16 patients (25%) required either further imaging and characterization, or follow up imaging, these included undetermined masses or nodules, while 43 patients (66%) required either reassurance or life style modification, which included extensive atherosclerotic changes, fatty liver or spondylolisthesis. CONCLUSIONS Colon cancer is one of the leading cause of mortality and morbidity in our Saudi Arabia community. Early detection of colon cancer and its precursor (i.e. polyps) is essential for successful management.

Diagnostic performance of computed tomography colonography in symptomatic patients and in patients with increased risk for colorectal disease

2006 ◽  
Vol 47 (9) ◽  
pp. 888-898 ◽  
Author(s):  
M. H. Reuterskiöld ◽  
A. Lasson ◽  
E. Svensson ◽  
A. Kilander ◽  
P.-O. Stotzer ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Diagnostic Performance ◽  
Colorectal Disease ◽  
Computed Tomography Colonography ◽  
Increased Risk

scholarly journals Feasibility of Computed Tomography Colonography as a Diagnostic Procedure in Colon Cancer Screening in India

2014 ◽  
Vol 15 (13) ◽  
pp. 5111-5116 ◽  
Author(s):  
Kanabagatte Nanjundappa Manjunath ◽  
Prabhu Karkala Gopalakrishna ◽  
Puttappa Chandrappa Siddalingaswamy
Keyword(s):  
Computed Tomography ◽  
Colon Cancer ◽  
Cancer Screening ◽  
Diagnostic Procedure ◽  
Colon Cancer Screening ◽  
Computed Tomography Colonography

Diagnostic performance of computed tomography colonography and colonoscopy: a prospective and validated analysis of 231 paired examinations

2007 ◽  
Vol 48 (8) ◽  
pp. 831-837 ◽  
Author(s):  
R. B. Arnesen ◽  
E. von Benzon ◽  
S. Adamsen ◽  
L. B. Svendsen ◽  
H. O. Raaschou ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Diagnostic Performance ◽  
Helical Ct ◽  
Cost Effective ◽  
Colorectal Polyps ◽  
Low Grade ◽  
Ct Scanner ◽  
Computed Tomography Colonography ◽  
First Choice ◽  
Effective Use

Background: Detection of colorectal tumors with computed tomography colonography (CTC) is an alternative to conventional colonoscopy (CC), and clarification of the diagnostic performance is essential for cost-effective use of both technologies. Purpose: To evaluate the diagnostic performance of CTC compared with CC. Material and Methods: 231 consecutive CTCs were performed prior to same-day scheduled CC. The radiologist and endoscopists were blinded to each other's findings. Patients underwent a polyethylene glycol bowel preparation, and were scanned in prone and supine positions using a single-detector helical CT scanner and commercially available software for image analysis. Findings were validated (matched) in an unblinded comparison with video-recordings of the CCs and re-CCs in cases of doubt. Results: For patients with polyps ⩾5 mm and ⩾10 mm, the sensitivity was 69% (95% CI 58–80%) and 81% (68–94%), and the specificity was 91% (84–98%) and 98% (93–100%), respectively. For detection of polyps ⩾5 mm and ⩾10 mm, the sensitivity was 66% (57–75%) and 77% (65–89%). A flat, elevated low-grade carcinoma was missed by CTC. One cancer relapse was missed by CC, and a cecal cancer was missed by an incomplete CC and follow-up double-contrast barium enema. Conclusion: CC was superior to CTC and should remain first choice for the diagnosis of colorectal polyps. However, for diagnosis of lesions ⩾10 mm, CTC and CC should be considered as complementary methods.

Contrast-Enhanced Computed Tomography Colonography in Preoperative Distinction between T1-T2 and T3-T4 Staging of Colon Cancer

2013 ◽  
Vol 20 (5) ◽  
pp. 590-595 ◽  
Author(s):  
Nicola Flor ◽  
Miriam Mezzanzanica ◽  
Paolo Rigamonti ◽  
Elena Guerini Rocco ◽  
Silvano Bosari ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Colon Cancer ◽  
Computed Tomography Colonography ◽  
Contrast Enhanced ◽  
Enhanced Computed Tomography ◽  
Contrast Enhanced Computed Tomography
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