scholarly journals Functional networks are impaired by elevated tau-protein but reversible in a regulatable Alzheimer’s disease mouse model

2019 ◽  
Vol 14 (1) ◽  
Author(s):  
Claudia Green ◽  
Astrid Sydow ◽  
Stefanie Vogel ◽  
Marta Anglada-Huguet ◽  
Dirk Wiedermann ◽  
...  
2015 ◽  
Vol 11 (7S_Part_14) ◽  
pp. P636-P636
Author(s):  
Claudia Luna-Herrera ◽  
Azucena Vázquez-Aguilar ◽  
Maria del Carmen Cardenas-Aguayo ◽  
Fidel de la Cruz-López ◽  
Amparo Viramontes-Pintos ◽  
...  

2021 ◽  
Author(s):  
Mohammad Ali Taheri ◽  
Sara Torabi ◽  
Noushin Nabavi ◽  
Farid Semsarha

Abstract Background: Alzheimer’s Disease (AD) is one of the most common causes of dementia, imposing large financial and psychological burdens on nations worldwide. Thus, we are in dire need for new treatment strategies or drugs for this disease. The aim of this study is to investigate the effects of a novel non-pharmacological method in the treatment of Alzheimer’s disease, based on Taheri's Consciousness Field approach. This approach works at the level of cellular and molecular processes and is tested in neuronal cells of AD mouse models. Methods: In this study, we established a neuron cell culture from an AD mouse model as well as a traumatic brain injury mouse model. We then measured changes in amyloidopathy, tau protein content, microtubule assembly, neuronal cell survival, and finally behavior of TBI mice in elevated Plus Maze under treatment of the Faradarmani Consciousness Field (FCF). Results: According to the results of this study, treatment of neural cell and mouse model of Alzheimer's disease by the FCF, leads to about complete survival of neural cell models and elimination of amyloidopathy and tau protein and remarkable behavioral improvement of the treated TBI mice model in the elevated plus maze. Conclusions: Based on the results, the FCF treatment suppresses AD development in the laboratory models. In this regard, conducting a human clinical study with the aim of introducing a new global complementary and alternative medicine in AD treatment is highly recommended.


2014 ◽  
Vol 10 ◽  
pp. P649-P649
Author(s):  
Juan Carlos Polanco ◽  
Benjamin James Scicluna ◽  
Andrew Francis Hill ◽  
Jürgen Götz

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