scholarly journals Two-stage window screening and development trajectories in early identification of autism spectrum disorder among Han Chinese children

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
For-Wey Lung ◽  
Bih-Ching Shu
Keyword(s):  
Autism Spectrum Disorder ◽  
Cohort Study ◽  
Language Development ◽  
Birth Cohort ◽  
Screening Method ◽  
Autism Spectrum ◽  
Birth Cohort Study ◽  
Two Stage ◽  
Window Screening ◽  
Taiwan Birth Cohort Study

Abstract Objective An understanding of the trajectory and norm of development in children is needed in order to understand the concept of the spectrum in the diagnosis of autism spectrum disorder (ASD). Children’s developmental growth trajectory was measured from six to 66 months in the Taiwan Birth Cohort Study dataset (N = 11,145). Additionally, over 4 years of follow-up, the negative predictive value of using the Parental Concern Checklist and Taiwan Birth Cohort Study Developmental Instrument was also investigated as the first stage of screening in a two-stage window screening method for ASD diagnosis. Results The growth trajectory showed that children’s language development began to increase at 18 months, and peaked at 36 months. On the other hand, social development showed steady growth from 18 to 66 months. The increase in the trajectory of children’s language development prior to age three, when compared with other developmental dimensions, may increase the difficulty of diagnosing ASD. The two-stage window screening method can be used in settings where the screening sample is large, such as in community or primary care settings, and has been found to be time- and cost-efficient. Better understanding of children’s developmental trajectory can enhance detection and intervention for ASD.

Psychiatric disorders diagnosed in adolescence and subsequent long-term exclusion from education, employment or training: longitudinal national birth cohort study

2021 ◽  
pp. 1-6
Author(s):  
Ida Ringbom ◽  
Jaana Suvisaari ◽  
Antti Kääriälä ◽  
Andre Sourander ◽  
Mika Gissler ◽  
...  
Keyword(s):  
Autism Spectrum Disorder ◽  
Cohort Study ◽  
Psychiatric Disorders ◽  
Birth Cohort ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Birth Cohort Study ◽  
Comprehensive Overview ◽  
Important Indicator

Background Long-term ‘not in education, employment or training’ (NEET) status is an important indicator of youth marginalisation. Aims To carry out a comprehensive overview of the associations between different psychiatric illnesses and long-term NEET status. Method We used the register-based 1987 Finnish Birth Cohort study, which includes all live births in Finland during that year. The analyses comprised 55 273 individuals after exclusions for intellectual disability, death or emigration. We predicted that psychiatric disorders, diagnosed by specialist services between 1998 and 2007 when the cohort were 10–20 years of age, would be associated with subsequent long-term NEET (defined as NEET for at least 5 years between 2008 and 2015, when they were 20–28 years of age). Results In total, 1438 individuals (2.6%) were long-term NEET during follow-up and the associations between long-term NEET and the 11 diagnostic categories we studied were statistically significant (P < 0.001). In multivariate models we included sociodemographic characteristics and upper secondary education as covariates, and the highest effect sizes, measured by odds ratios (OR) with 95% confidence intervals (CI), were found for psychosis (OR = 12.0, 95% CI 9.5–15.2) and autism spectrum disorder (OR = 17.3, 95% CI 11.5–26.0). If individuals had not successfully completed this education, 70.6% of those with autism spectrum disorder and 48.4% of those with psychosis were later long-term NEET. Conclusions Adolescents who receive treatment for psychiatric disorders, particularly autism spectrum disorder or psychosis, need support to access education and employment. This could help to prevent marginalisation in early adulthood.

scholarly journals The disparity of maternal childcare pressure and quality of life between children diagnosed with autism spectrum disorder and developmental delay in the Chinese culture context: Taiwan Birth Cohort pilot Study

2020 ◽  
Author(s):  
For-Wey Lung ◽  
Bih-Ching Shu ◽  
Tung-Liang Chiang ◽  
Shio-Jean Lin
Keyword(s):  
Quality Of Life ◽  
Autism Spectrum Disorder ◽  
Cohort Study ◽  
Family Support ◽  
Birth Cohort ◽  
Cultural Context ◽  
Structural Equation ◽  
Autism Spectrum ◽  
Birth Cohort Study

Abstract Background: Many studies have shown that parents express higher stress when taking care of children with autism spectrum disorder (ASD). However, cultural context should be taken into consideration when investigating children's diagnosis and parental quality of life (QOL). Therefore, this study aimed to investigate the pathway relationship among parental QOL, child development, ASD and developmental delay (DD) risk at 3 years of age, and ASD or DD diagnosis 2.5 years later.Methods: A birth cohort study database collected at age 3 and 5.5 years was used (N=1618). The Modified Checklist of Autism in Toddlers, Taiwan Birth Cohort Study Developmental Instrument, and the Short Form-36 was used to assess ASD risk, developmental condition (DD risk), and parental QOL, respectively.Results: By structural equation modeling, an indirect influence was found between children's diagnosis and maternal health QOL. Mothers of children diagnosed with ASD perceived more family support, and those who perceived more family support had better health QOL. Conversely, mothers of children diagnosed with DD perceived higher childcare pressure, and mothers who perceived higher childcare pressure had worse health QOL.Conclusions: The differences in mother's experience when their children are diagnosed with DD and ASD can only be found in pathway analysis, showing the importance of structural equation models. Healthcare personnel should take into consideration the cultural context of the families we encounter, and the vital role family support plays should be taken into consideration when interacting with families from collectivism cultures.

Diagnostic And Cultural Considerations to Improve The Identification Of Autism Spectrum Disorder Among Han Chinese Children

2020 ◽  
Author(s):  
For-Wey Lung ◽  
Bih-Ching Shu
Keyword(s):  
Autism Spectrum Disorder ◽  
Language Development ◽  
Screening Method ◽  
Autism Spectrum ◽  
Developmental Trajectory ◽  
Spectrum Disorder ◽  
Growth Trajectory ◽  
Fine Motor ◽  
Birth Cohort Study ◽  
Cost Efficient

Abstract Objective: The trajectory and norm of children's development is needed to understand the idea of spectrum in autism spectrum disorder (ASD) diagnosis. The children's developmental growth trajectory from six to 66 months in the developmental dimensions of growth motor, fine motor, language, and social communication is investigated in the Taiwan Birth Cohort Study dataset (N=11,145).Results: The growth trajectory showed children's language development began to incline at 18 months, and peaked at 36 months. On the other hand, children's social development showed a steady growth from 18 to 66 months. Furthermore, the increase in the trajectory of children's language development prior to age three, compared to other developmental dimensions, may also increase the difficulty of diagnosis. The two-stage window screening method can be used in settings where the screening sample is larger in size, such as the community or primary care settings, and has found to be more time and cost efficient. Better understanding of the children's developmental trajectory can enhance autism spectrum disorder detection and intervention.

scholarly journals Gestational Age, Perinatal Characteristics, and Autism Spectrum Disorder: A Birth Cohort Study

2020 ◽  
Vol 220 ◽  
pp. 175-183.e8 ◽  
Author(s):  
Jane E. Brumbaugh ◽  
Amy L. Weaver ◽  
Scott M. Myers ◽  
Robert G. Voigt ◽  
Slavica K. Katusic
Keyword(s):  
Autism Spectrum Disorder ◽  
Cohort Study ◽  
Birth Cohort ◽  
Gestational Age ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Birth Cohort Study

scholarly journals Association between maternal shift work and infant neurodevelopmental outcomes: results from the Taiwan Birth Cohort Study with propensity-score-matching analysis

2019 ◽  
Vol 48 (5) ◽  
pp. 1545-1555
Author(s):  
Chih-Fu Wei ◽  
Mei-Huei Chen ◽  
Ching-Chun Lin ◽  
Yueliang Leon Guo ◽  
Shio-Jean Lin ◽  
...  
Keyword(s):  
Cohort Study ◽  
Propensity Score ◽  
Birth Cohort ◽  
Shift Work ◽  
Fine Motor ◽  
Birth Cohort Study ◽  
Work Status ◽  
Neurodevelopmental Outcomes ◽  
Gross Motor ◽  
Taiwan Birth Cohort Study

Abstract Background Maternal shift work is associated with preterm delivery, small-for-gestational-age new-borns, childhood obesity and future behavioural problems. However, the adverse effects on and interactions of maternal shift work with infant neurodevelopment remain uncertain. Therefore, we examined the associations between maternal-shift-work status and infant neurodevelopmental parameters. Methods The Taiwan Birth Cohort Study is a nationwide birth cohort study following representatively sampled mother–infant pairs in 2005. The participants’ development and exposure conditions were assessed by home interviews with structured questionnaires at 6 and 18 months of age. Propensity scores were calculated with predefined covariates for 1:1 matching. Multivariate conditional logistic regression and the Cox proportional-hazards model were used to examine the association between maternal-shift-work status and infant neurodevelopmental-milestone-achievement status. Results In this study, 5637 term singletons were included, with 2098 cases selected in the propensity-score-matched subpopulation. Persistent maternal shift work was associated with increased risks of delays in gross-motor neurodevelopmental milestones [aOR = 1.36, 95% confidence interval (CI) = 1.06–1.76 for walking steadily], fine-motor neurodevelopmental milestones (aOR = 1.39, 95% CI = 1.07–1.80 for scribbling) and social neurodevelopmental milestones (aOR = 1.35, 95% CI = 1.03–1.76 for coming when called upon). Moreover, delayed gross-motor and social development were identified in the propensity-score-matched sub-cohort. Conclusions This study shows negative associations between maternal shift work and delayed neurodevelopmental-milestone achievement in the gross-motor, fine-motor and social domains at 18 months. Future research is necessary to elucidate the possible underlying mechanisms and long-term health effects.

scholarly journals From dissociative experience and internet use to happiness: A Taiwan Birth Cohort Study

2020 ◽  
Author(s):  
For-Wey Lung ◽  
Bih-Ching Shu ◽  
Tung-Liang Chiang ◽  
Shio-Jean Lin
Keyword(s):  
Cohort Study ◽  
Protective Factors ◽  
Birth Cohort ◽  
Internet Use ◽  
Depressive Mood ◽  
High Risk Group ◽  
Birth Cohort Study ◽  
Self Identity ◽  
Study Results ◽  
Taiwan Birth Cohort Study

Abstract Background Functional and excessive use of internet is hard to distinguish, and internet use can affect adolescents’ development of self-identity. The aim of our study was to investigate the pathway relationship of the risk and protective factors of internet use, including mother care, absorptive dissociative trait, having been bullied, exercise, self-perceived depressive mood and happiness of 12-year-old adolescents. Methods The Taiwan Birth Cohort Study dataset, which used a national household probability sampling method and included 17,694 12-years-old adolescents, was used for this study. Results Our results showed 5.3% adolescents reported to spend more than five hours online during schooldays. Additionally, adolescents that spend more than five hours online during schooldays tended to have higher absorptive trait, perceived less care from mothers, more likely to have been bullied, expressed higher level of depressed mood, which leads to lower level of perceived happiness. Conclusions Adolescents that spend more than 5 hours online during schooldays, compared to those that spent less than an hour online, were more likely to have been bullied and affect their level of happiness, showing that they may be a group of higher concern. Since parental care and regular exercise are protective factors for internet addiction, it should be promoted to all adolescents, especially those in the high risk group, to prevent them from being addicted online.

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