ABT-126 monotherapy in mild-to-moderate Alzheimer’s dementia: randomized double-blind, placebo and active controlled adaptive trial and open-label extension

Laura M. Gault; Robert A. Lenz; Craig W. Ritchie; Andreas Meier; Ahmed A. Othman; Qi Tang; Scott Berry; Yili Pritchett; Weining Z. Robieson

doi:10.1186/s13195-016-0210-1

ABT-126 monotherapy in mild-to-moderate Alzheimer’s dementia: randomized double-blind, placebo and active controlled adaptive trial and open-label extension

Alzheimer s Research & Therapy ◽

10.1186/s13195-016-0210-1 ◽

2016 ◽

Vol 8 (1) ◽

Cited By ~ 15

Author(s):

Laura M. Gault ◽

Robert A. Lenz ◽

Craig W. Ritchie ◽

Andreas Meier ◽

Ahmed A. Othman ◽

...

Keyword(s):

Alzheimer’S Dementia ◽

Open Label ◽

Double Blind ◽

Alzheimer's Dementia ◽

Double Blind Placebo ◽

Open Label Extension ◽

Adaptive Trial

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The Effects of Rasagiline on Glucose Metabolism and Cognition and Their Relationship to Tau Burden in a Double-Blind, Placebo-Controlled Phase Ii Clinical Trial of Participants with Alzheimer's Dementia

SSRN Electronic Journal ◽

10.2139/ssrn.3544838 ◽

2020 ◽

Author(s):

Dawn Matthews ◽

Aaron Ritter ◽

Ronald G. Thomas ◽

Randolph D. Andrews ◽

Ana S. Lukic ◽

...

Keyword(s):

Clinical Trial ◽

Glucose Metabolism ◽

Phase Ii ◽

Alzheimer’S Dementia ◽

Phase Ii Clinical Trial ◽

Double Blind ◽

Alzheimer's Dementia ◽

Double Blind Placebo

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Oxcarbazepine adjunctive therapy for partial seizures in Japanese pediatric patients: a randomized double-blind placebo-controlled study and open-label extension study

Epilepsy & Seizure ◽

10.3805/eands.11.30 ◽

2019 ◽

Vol 11 (1) ◽

pp. 30-45

Author(s):

Tateki Fujiwara ◽

Rie Teshima ◽

Ikuo Sugiyama ◽

Ken Tsuchida ◽

Yoko Ohtsuka

Keyword(s):

Adjunctive Therapy ◽

Pediatric Patients ◽

Extension Study ◽

Controlled Study ◽

Partial Seizures ◽

Open Label ◽

Double Blind ◽

Double Blind Placebo ◽

Open Label Extension

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Body composition and weight changes after ivacaftor treatment in adults with cystic fibrosis carrying the G551 D cystic fibrosis transmembrane conductance regulator mutation: A double-blind, placebo-controlled, randomized, crossover study with open-label extension

Nutrition ◽

10.1016/j.nut.2020.111124 ◽

2021 ◽

Vol 85 ◽

pp. 111124

Author(s):

Susannah J. King ◽

Audrey C. Tierney ◽

Deirdre Edgeworth ◽

Dominic Keating ◽

Elyssa Williams ◽

...

Keyword(s):

Cystic Fibrosis ◽

Transmembrane Conductance Regulator ◽

Weight Changes ◽

Transmembrane Conductance ◽

Open Label ◽

Double Blind ◽

Double Blind Placebo ◽

Open Label Extension ◽

Cystic Fibrosis Transmembrane ◽

Randomized Crossover Study

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72-Week Safety and Tolerability of Dimethyl Fumarate in Japanese Patients with Relapsing-remitting Multiple Sclerosis: Analysis of the Randomised, Double Blind, Placebo-Controlled, Phase III APEX Study and its Open-Label Extension

Advances in Therapy ◽

10.1007/s12325-018-0788-8 ◽

2018 ◽

Vol 35 (10) ◽

pp. 1598-1611 ◽

Cited By ~ 9

Author(s):

Hirofumi Ochi ◽

Masaaki Niino ◽

Yasuhiro Onizuka ◽

Katsutoshi Hiramatsu ◽

Masakazu Hase ◽

...

Keyword(s):

Multiple Sclerosis ◽

Japanese Patients ◽

Dimethyl Fumarate ◽

Phase Iii ◽

Open Label ◽

Double Blind ◽

Double Blind Placebo ◽

Relapsing Remitting ◽

Open Label Extension ◽

Relapsing Remitting Multiple Sclerosis

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Efficacy and safety of esmirtazapine in adult outpatients with chronic primary insomnia: a randomized, double-blind placebo-controlled study and open-label extension

Journal of Clinical Sleep Medicine ◽

10.5664/jcsm.8526 ◽

2020 ◽

Vol 16 (9) ◽

pp. 1455-1467 ◽

Cited By ~ 2

Author(s):

Neely Ivgy-May ◽

Goeran Hajak ◽

Gonnie van Osta ◽

Sabine Braat ◽

Qing Chang ◽

...

Keyword(s):

Primary Insomnia ◽

Controlled Study ◽

Efficacy And Safety ◽

Open Label ◽

Double Blind ◽

Double Blind Placebo ◽

Open Label Extension

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Mo1945 Intragastric Injection of Botulinum Toxin a to Treat Obesity: Mechanism of Action and a Randomized, Double-Blind, Placebo-Controlled Phase II Trial With Open-Label Extension Study

Gastroenterology ◽

10.1016/s0016-5085(16)32787-1 ◽

2016 ◽

Vol 150 (4) ◽

pp. S823

Author(s):

Duan Chen ◽

Magnus K. Olsen ◽

Magnus Strommen ◽

Helene Johannessen ◽

Hege T. Bjoru ◽

...

Keyword(s):

Botulinum Toxin ◽

Phase Ii ◽

Mechanism Of Action ◽

Phase Ii Trial ◽

Botulinum Toxin A ◽

Open Label ◽

Toxin A ◽

Double Blind ◽

Double Blind Placebo ◽

Open Label Extension

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Effect of Sildenafil Citrate on the Male Sexual Experience Assessed with the Sexual Experience Questionnaire: A Multicenter, Double‐Blind, Placebo‐Controlled Trial with Open‐Label Extension

Journal of Sexual Medicine ◽

10.1111/j.1743-6109.2008.00879.x ◽

2008 ◽

Vol 5 (8) ◽

pp. 1955-1964 ◽

Cited By ~ 18

Author(s):

LeRoy A. Jones ◽

Ira W. Klimberg ◽

James G. McMurray ◽

Rebecca Padula ◽

Li‐Jung Tseng ◽

...

Keyword(s):

Sexual Experience ◽

Controlled Trial ◽

Sildenafil Citrate ◽

Open Label ◽

Double Blind ◽

Double Blind Placebo ◽

Open Label Extension ◽

Experience Questionnaire

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Interleukin-2 diphtheria fusion protein (dab486il-2) in refractory rheumatoid arthritis a double-blind, placebo-controlled trial with open-label extension

Arthritis & Rheumatism ◽

10.1002/art.1780380902 ◽

1995 ◽

Vol 38 (9) ◽

pp. 1177-1186 ◽

Cited By ~ 49

Author(s):

Larry W. Moreland ◽

K. Lea Sewell ◽

David E. Trentham ◽

R. Pat Bucy ◽

William F. Sullivan ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Fusion Protein ◽

Controlled Trial ◽

Interleukin 2 ◽

Open Label ◽

Double Blind ◽

Double Blind Placebo ◽

Refractory Rheumatoid Arthritis ◽

Open Label Extension

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An open-label extension study following the HRM4396B/3001 study (a double-blind, placebo-controlled, parallel arms, dose response study of two doses of HMR4396 versus placebo for anaemia in subjects treated with chemotherapy)

http://isrctn.org/> ◽

10.1186/isrctn41606826 ◽

2013 ◽

Author(s):

Chris Freitag

Keyword(s):

Dose Response ◽

Extension Study ◽

Open Label ◽

Double Blind ◽

Double Blind Placebo ◽

Open Label Extension ◽

Dose Response Study

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Enzyme replacement therapy for mucopolysaccharidosis VI: A phase 3, randomized, double-blind, placebo-controlled, multinational study of recombinant human N-acetylgalactosamine 4-sulfatase (recombinant human arylsulfatase B or rhASB) and follow-on, open-label extension study

The Journal of Pediatrics ◽

10.1016/j.jpeds.2005.12.014 ◽

2006 ◽

Vol 148 (4) ◽

pp. 533-539.e6 ◽

Cited By ~ 256

Author(s):

Paul Harmatz ◽

Roberto Giugliani ◽

Ida Schwartz ◽

Nathalie Guffon ◽

Elisa Leão Teles ◽

...

Keyword(s):

Multinational Study ◽

Open Label ◽

Phase 3 ◽

Double Blind ◽

Double Blind Placebo ◽

Enzyme Replacement ◽

Arylsulfatase B ◽

Open Label Extension ◽

Mucopolysaccharidosis Vi ◽

Human Arylsulfatase

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