scholarly journals Persistence of the protective immunity and kinetics of the isotype specific antibody response against the viral nucleocapsid protein after experimental Schmallenberg virus infection of sheep

2015 ◽  
Vol 46 (1) ◽  
Author(s):  
Antoine Poskin ◽  
Stephanie Verite ◽  
Loic Comtet ◽  
Yves Van der Stede ◽  
Brigitte Cay ◽  
...  
Keyword(s):  
Virus Infection ◽  
Antibody Response ◽  
Specific Antibody ◽  
Nucleocapsid Protein ◽  
Protective Immunity ◽  
Schmallenberg Virus ◽  
Specific Antibody Response ◽  
Kinetics Of ◽  
Viral Nucleocapsid

scholarly journals Immunization with Pneumocystis carinii gpA Is Immunogenic but Not Protective in a Mouse Model of P. carinii Pneumonia

1998 ◽  
Vol 66 (7) ◽  
pp. 3179-3182 ◽  
Author(s):  
Francis Gigliotti ◽  
James A. Wiley ◽  
Allen G. Harmsen
Keyword(s):  
T Cell ◽  
Animal Models ◽  
Mouse Model ◽  
Antibody Response ◽  
Specific Antibody ◽  
Protective Immunity ◽  
Subunit Vaccine ◽  
Pneumocystis Carinii ◽  
Specific Antibody Response ◽  
A Subunit

ABSTRACT Immunization with whole Pneumocystis carinii has been shown to protect mice from the development of P. carinii pneumonia (PCP) when they are subsequently immunosuppressed and challenged with viable organisms. To determine whether these results could be duplicated by using a subunit vaccine, we examined the immunogenicity and efficacy of an immunization strategy based on P. carinii gpA. This antigen was chosen for study because passive immunoprophylaxis, based on gpA, has been shown to be partially protective in various animal models of infection. Immunization with gpA produced an anti-gpA specific antibody response comparable to that resulting from immunization with whole organisms. However, in contrast to immunization with whole P. carinii, which was protective, immunization with gpA did not protect T-cell-depleted mice from the development of PCP. These studies suggest that other antigens in addition to gpA need to be evaluated for their role in protective immunity against P. carinii.

scholarly journals Whole Transcriptome Profiling Identifies CD93 and Other Plasma Cell Survival Factor Genes Associated with Measles-Specific Antibody Response after Vaccination

PLoS ONE ◽  
2016 ◽  
Vol 11 (8) ◽  
pp. e0160970 ◽  
Author(s):  
Iana H. Haralambieva ◽  
Michael T. Zimmermann ◽  
Inna G. Ovsyannikova ◽  
Diane E. Grill ◽  
Ann L. Oberg ◽  
...  
Keyword(s):  
Antibody Response ◽  
Cell Survival ◽  
Plasma Cell ◽  
Specific Antibody ◽  
Transcriptome Profiling ◽  
Specific Antibody Response ◽  
Survival Factor ◽  
Whole Transcriptome ◽  
Cell Survival Factor

scholarly journals A highly specific antibody response after protein prime-peptide boost immunization with Eppin/B-cell epitope in mice

2011 ◽  
Vol 7 (8) ◽  
pp. 849-855 ◽  
Author(s):  
Zhengqiong Chen ◽  
Wei He ◽  
Yuzhang Wu ◽  
Ping Yan ◽  
Haiyang He ◽  
...  
Keyword(s):  
Antibody Response ◽  
B Cell ◽  
Specific Antibody ◽  
Cell Epitope ◽  
Specific Antibody Response ◽  
B Cell Epitope ◽  
Boost Immunization
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