In this article public-private partnership issues are considered. The purpose is to offer a partnership trio model for the Republic of Kazakhstan. This is possible taking into account international experience, as well as by exploring the possibilities of partnership among government agencies, business entities and scientific organizations within the national economic system. A model of forming a trio partnership, which is one of the most developed forms of public-private partnership, has been proposed. This is important from the point of view of the development of the state as a whole. The article also discusses the forms of contribution of each of the participants of the partnership to achieve the goal of improving efficiency. The research methodology is based on the developments of scientists in the field of partnership between science and business, institutional economics, the use of an integrated approach and the principles of dialectics to identify the essential characteristics of partnerships, as well as the conditions for their successful application in the national economy.