scholarly journals Assessment of naive indolent lymphoma using whole-body diffusion-weighted imaging and T2-weighted MRI: results of a prospective study in 30 patients

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Gil-Sun Hong ◽  
Eun Jin Chae ◽  
Jin-Sook Ryu ◽  
Sun Young Chae ◽  
Hyo Sang Lee ◽  
...  
Keyword(s):  
Prospective Study ◽  
Fdg Pet ◽  
Diffusion Weighted Imaging ◽  
High Specificity ◽  
Whole Body ◽  
Indolent Lymphoma ◽  
Body Regions ◽  
Diffusion Weighted ◽  
Pet Ct ◽  
Fdg Pet Ct

Abstract Background We prospectively evaluated the diagnostic utility of whole-body diffusion-weighted imaging with background body signal suppression and T2-weighted short-tau inversion recovery MRI (WB-DWIBS/STIR) for the pretherapeutic staging of indolent lymphoma in 30 patients. Methods This prospective study included 30 treatment-naive patients with indolent lymphomas who underwent WB-DWIBS/STIR and conventional imaging workup plus biopsy. The pretherapeutic staging agreement, sensitivity, and specificity of WB-DWIBS/STIR were investigated with reference to the multimodality and multidisciplinary consensus review for nodal and extranodal lesions excluding bone marrow. Results In the pretherapeutic staging, WB-DWIBS/STIR showed very good agreement (κ = 0.96; confidence interval [CI], 0.88–1.00), high sensitivity (93.4–95.1%), and high specificity (99.0–99.4%) for the whole-body regions. These results were similar to those of 18F-FDG-PET/CT, except for the sensitivity for extranodal lesions. For extranodal lesions, WB-DWIBS/STIR showed higher sensitivity compared to 18F-FDG-PET/CT for the whole-body regions (94.9–96.8% vs. 79.6–86.3%, P = 0.058). Conclusion WB-DWIBS/STIR is an effective modality for the pretherapeutic staging of indolent lymphoma, and it has benefits when evaluating extranodal lesions, compared with 18F-FDG-PET/CT.

Whole-body diffusion-weighted imaging compared with FDG-PET/CT in staging of lymphoma patients

2011 ◽  
Vol 52 (2) ◽  
pp. 173-180 ◽  
Author(s):  
Goran Abdulqadhr ◽  
Daniel Molin ◽  
Gunnar Åström ◽  
Madis Suurküla ◽  
Lars Johansson ◽  
...  
Keyword(s):  
Fdg Pet ◽  
Diffusion Weighted Imaging ◽  
Whole Body ◽  
Diffusion Weighted ◽  
Pet Ct ◽  
Fdg Pet Ct

Prospective comparison of 18-FDG PET/CT and whole-body diffusion-weighted MRI in the assessment of multiple myeloma

2020 ◽  
Vol 99 (12) ◽  
pp. 2869-2880
Author(s):  
Charles Mesguich ◽  
Cyrille Hulin ◽  
Valerie Latrabe ◽  
Axelle Lascaux ◽  
Laurence Bordenave ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Fdg Pet ◽  
Whole Body ◽  
Diffusion Weighted Mri ◽  
Diffusion Weighted ◽  
Prospective Comparison ◽  
Pet Ct ◽  
Fdg Pet Ct

Non–Small Cell Lung Cancer: Whole-Body MR Examination for M-Stage Assessment—Utility for Whole-Body Diffusion-weighted Imaging Compared with Integrated FDG PET/CT

Radiology ◽  
2008 ◽  
Vol 248 (2) ◽  
pp. 643-654 ◽  
Author(s):  
Yoshiharu Ohno ◽  
Hisanobu Koyama ◽  
Yumiko Onishi ◽  
Daisuke Takenaka ◽  
Munenobu Nogami ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Fdg Pet ◽  
Diffusion Weighted Imaging ◽  
Small Cell ◽  
Whole Body ◽  
Small Cell Lung ◽  
Pet Ct ◽  
Fdg Pet Ct

Diagnostic performances of FDG-PET/CT and diffusion-weighted imaging indices for differentiating benign pheochromocytoma from other benign adrenal tumors

2014 ◽  
Vol 40 (6) ◽  
pp. 1655-1665 ◽  
Author(s):  
Masatoyo Nakajo ◽  
Masayuki Nakajo ◽  
Yoshihiko Fukukura ◽  
Megumi Jinguji ◽  
Toshikazu Shindo ◽  
...  
Keyword(s):  
Fdg Pet ◽  
Diffusion Weighted Imaging ◽  
Adrenal Tumors ◽  
Diffusion Weighted ◽  
Pet Ct ◽  
Fdg Pet Ct ◽  
And Diffusion

scholarly journals Staging of Primary Abdominal Lymphomas: Comparison of Whole-Body MRI with Diffusion-Weighted Imaging and18F-FDG-PET/CT

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Alessandro Stecco ◽  
Francesco Buemi ◽  
Martina Quagliozzi ◽  
Mariangela Lombardi ◽  
Alberto Santagostino ◽  
...  
Keyword(s):  
Fdg Pet ◽  
Weighted Kappa ◽  
Whole Body ◽  
Gastrointestinal Lymphoma ◽  
Predictive Values ◽  
Whole Body Mri ◽  
Diffusion Weighted ◽  
Pet Ct ◽  
Fdg Pet Ct ◽  
Kappa Agreement

Background. The purpose of this study was to compare the accuracy of whole-body MRI with diffusion-weighted sequences (WB-DW-MRI) with that of18F-FDG-PET/CT in the staging of patients with primary gastrointestinal lymphoma.Methods. This retrospective study involved 17 untreated patients with primary abdominal gastrointestinal lymphoma. All patients underwent18F-FDG-PET/CT and WB-DW-MRI. Histopathology findings or at least 6 months of clinical and radiological follow-up was the gold standard. The Musshoff-modified Ann Arbor system was used for staging, and diagnostic accuracy was evaluated on a per-node basis.Results. WB-DW-MRI exhibited 100% sensitivity, 96.3% specificity, and 96.1% and 100% positive and negative predictive values (PPV and NPV), respectively. The sensitivity, specificity, and PPV and NPV of PET/CT were 95.9%, 100%, and 100% and 96.4%, respectively. There were no statistically significant differences between the two techniquesp=0.05. The weighted kappa agreement statistics with a 95% confidence interval were 0.97 (0.95–0.99) between the two MRI readers and 0.87 (0.82–0.92) between the two methods.Conclusions. WB-DW-MRI appears to have a comparable diagnostic value to18F-FDG-PET/CT in staging patients with gastrointestinal lymphoma.

Lesion concordance, image quality and artefacts in PET/CT

2010 ◽  
Vol 49 (04) ◽  
pp. 129-137 ◽  
Author(s):  
B. J. Krause ◽  
S. M. Eschmann ◽  
K. U. Juergens ◽  
H. Kuehl ◽  
A. C. Pfannenberg ◽  
...  
Keyword(s):  
Image Quality ◽  
Fdg Pet ◽  
Whole Body ◽  
Ct Scans ◽  
Intravenous Contrast ◽  
Metal Implants ◽  
Body Regions ◽  
Pet Ct ◽  
Fdg Pet Ct ◽  
Attenuation Corrected

Summary Aim: This study had three major objectives: 1.) to record the number of concordant (both in PET and CT) pathological lesions in different body regions/organs, 2.) to evaluate the image quality and 3.) to determine both, the quantity and the quality of artefacts in whole body FDG PET/CT scans. Patients, methods: Routine whole body scans of 353 patients referred to FDG-PET/ CT exams at 4 university hospitals were employed. All potentially malignant lesions in 13 different body regions/organs were classified as either concordant or suspicious in FDG-PET or CT only. In the latter case the diagnostic relevance of this disparity was judged. The image quality in PET and CT was rated as a whole and separately in 5 different body regions. Furthermore we investigated the frequency and site of artefacts caused by metal implants and oral or intravenous contrast media as well as the subjective co-registration quality (in 4 body regions) and the diagnostic impact of such artefacts or misalignment. In addition, the readers rated the diagnostic gain of adding the information from the other tomographic method. Results: In total 1941 lesions (5.5 per patient) were identified, 1094 (56%) out of which were concordant. 602 (71%) out of the 847 remaining lesions were detected only with CT, 245 (29%) were only PET-positive. As expected, CT particularly depicted the majority of lesions in the lungs and abdominal organs. However, the diagnostic relevance was greater with PET-only positive lesions. Most of the PET/CT scans were performed with full diagnostic CT including administration of oral and intravenous contrast media (> 80%). The image quality in PET and CT was rated excellent. Artefacts occurred in more than 60% of the scans and were mainly due to (dental) metal implants and contrast agent. Nevertheless there was almost no impact on diagnostic confidence if reading of the non attenuation corrected PET was included. The co-registration quality in general was also rated as excellent. Misalignment mostly occurred due to patient motion and breathing and led to diagnostic challenges in about 4% of all exams. The diagnostic gain of adding PET to a CT investigation was rated higher than vice versa. Conclusions: As the image quality in both PET and CT was more than satisfying, CT-artefacts almost never led to diagnostic uncertainties and serious misalignment rarely occurred, PET/CT can be considered as suitable for routine use and may replace single PET- and CT-scans. However, additional reading of the non attenuation corrected PET is mandatory to assure best possible diagnostic confidence in PET. Since approximately half of all lesions found in PET/CT were not concordant, at least in a setting with a diagnostic CT the exams need to be reported by both a nuclear medicine physician and a radiologist in consensus.

Comparison of FDG-PET/CT and MR with diffusion-weighted imaging for assessing peritoneal carcinomatosis from gastrointestinal malignancy

2012 ◽  
Vol 22 (7) ◽  
pp. 1479-1487 ◽  
Author(s):  
Michael Soussan ◽  
Gaëtan Des Guetz ◽  
Vincent Barrau ◽  
Vanessa Aflalo-Hazan ◽  
Gabriel Pop ◽  
...  
Keyword(s):  
Peritoneal Carcinomatosis ◽  
Fdg Pet ◽  
Diffusion Weighted Imaging ◽  
Gastrointestinal Malignancy ◽  
Diffusion Weighted ◽  
Pet Ct ◽  
Fdg Pet Ct
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