scholarly journals Corneal biomechanical changes in allergic conjunctivitis

2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Qian Wang ◽  
Yuqing Deng ◽  
Saiqun Li ◽  
Xinyue Du ◽  
Xuan Zhao ◽  
...  
Keyword(s):  
Allergic Conjunctivitis ◽  
Clinical Manifestations ◽  
Related Factors ◽  
Corneal Epithelial ◽  
Epithelial Thickness ◽  
Biomechanical Changes ◽  
Corneal Epithelial Thickness ◽  
Development Risk ◽  
Biomechanical Measurements ◽  
Corneal Tomography

Abstract Background To explore corneal biomechanical changes, identify related factors and determine early indicators of keratoconus (KC) development risk in allergic conjunctivitis (AC) patients. Methods A total of 50 patients, including 20 eyes without AC and 30 eyes with AC were enrolled in this study. All patients underwent a complete ocular examination, including evaluations of clinical manifestations of AC, corneal tomography and densitometry by Pentacam, corneal biomechanics by Corvis ST, and corneal and epithelial thickness mapping by RTvue optical coherence tomography (OCT). Results The index of surface variance (ISV), index of vertical asymmetry (IVA), keratoconus index (KI), index of height decentration (IHD) and Belin/Ambrosio enhanced ectasia total deviation index (BAD-D) were significantly higher in the AC group than in the non-allergic conjunctivitis (NAC) group (P < 0.05). The tomography and biomechanical index (TBI) was also significantly higher in the AC group (P = 0.04). The average epithelial thickness in the 2–7 mm annulus was significantly thinner in the AC group than in the NAC group (P < 0.05). The average densitometry of the total cornea and the anterior layer were higher in the AC group than in the NAC group (P < 0.001). The ISV, IVA, KI, IHD and BAD-D were significantly correlated with the TBI and changes in corneal epithelial thickness in AC patients (P < 0.05). The changes in epithelial thickness were closely related to the eye rubbing frequency and allergic sign scores (P < 0.05). Conclusions AC patients should be advised to routinely undergo corneal tomographic and biomechanical measurements, and the TBI could be used as an indicator of KC development risk in AC patients. Trial registration Corneal Biomechanical Changes of Allergic Conjunctivitis, NCT04299399. Registered March 3, 2020 - Retrospectively registered.

The effect of PRK on corneal epithelium thickness and pachmetry in treatment of myopia.

2018 ◽  
Vol 9 (SPL1) ◽  
Author(s):  
Furkaan Majied Hamied ◽  
Deyaa Neama Kadhim ◽  
Sohaib A Mahmood
Keyword(s):  
Refractive Error ◽  
Anterior Segment ◽  
Thickness Change ◽  
Corneal Epithelial ◽  
Epithelial Thickness ◽  
Refractive Outcomes ◽  
Epithelium Thickness ◽  
Profile Changes ◽  
Corneal Epithelial Thickness ◽  
Myopic Astigmatism

In order to facilitate the corneal stromal ablation in photorefractive keratectomy the epithelium is removed so corneal repair associated with changes in epithelium and stroma. To study the corneal epithelial thickness and pachymetry profile changes after photorefractive keratec­tomy (PRK) for myopia. Retrospective analysis of the postoperative corneal epithelial thickness and pachymetry profile changes in 22 eyes of 12 patients treated with PRK for myopia or myopic astigmatism. Corneal and epithelial thickness maps within the central 6 mm were obtained by anterior segment spectral-domain optical coherence tomography (SD-OCT) preop­eratively and at 3 months postoperatively. Correlations between pachymetry,epithelial thickness changes and the amount of correction,were analyzed.Compared to preoperative values,the central 2 mm and the paracentral 2 to 5 mm zone epithelium was 1 ± 2.85 and 1 ± 3.11 μm thicker,respec­tively,at 3 months postoperatively (P <.05). The spheri­cal equivalent (SE) changed from-2.80 ± 2.028 diop­ters (D) preoperatively to -0.40 ± 0.42 D at 3 months postoperatively. Females show greater postoperative epithelial thickening, 2.6 ± 3.77 μm,than males,0.34 ± 1.98 μm. There was a trend toward greater epithelial thickening with a larger amount of programmed SE correction, and thinner preoperative epithelium. No correlation between epithelial thickness change and postoperative change in refraction was detected.Negative correlation between between age, refractive error,with the pre and post-operative pachymetry. In general female pachymetry reading is higher than it in male.The corneal epithelial thickness in­creased after PRK up to 3 months postoperatively. It was affected by the amount of myopia treated, gender, and preoperative epithelial thickness. The refractive outcomes did not affected by the postoperative epithelial thickening. Negative correlation between between age, refractive error, with the pre and post-operative pachymetry. In general female pachymetry reading is higher than it in male.

Corneal Epithelial Thickness Intrasubject Repeatability and its Relation With Visual Limitation in Keratoconus

2019 ◽  
Vol 200 ◽  
pp. 255-262 ◽  
Author(s):  
Alfredo Vega-Estrada ◽  
Michael Mimouni ◽  
Elias Espla ◽  
Jorge Alió del Barrio ◽  
Jorge L. Alio
Keyword(s):  
Corneal Epithelial ◽  
Epithelial Thickness ◽  
Corneal Epithelial Thickness

Reliability and Reproducibility of Assessment of Corneal Epithelial Thickness by Fourier Domain Optical Coherence Tomography

2012 ◽  
Vol 53 (6) ◽  
pp. 2580 ◽  
Author(s):  
Gaurav Prakash ◽  
Amar Agarwal ◽  
Anjum Iqbal Mazhari ◽  
Mathangi Chari ◽  
Dhivya Ashok Kumar ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Fourier Domain ◽  
Optical Coherence ◽  
Corneal Epithelial ◽  
Epithelial Thickness ◽  
Corneal Epithelial Thickness

Evaluation of Corneal Epithelial Thickness Imaged by High Definition Optical Coherence Tomography in Healthy Eyes

Cornea ◽  
2019 ◽  
Vol 38 (1) ◽  
pp. 62-66 ◽  
Author(s):  
Elmira Baghdasaryan ◽  
Tudor C. Tepelus ◽  
Kenneth M. Marion ◽  
Homayoun Bagherinia ◽  
SriniVas R. Sadda ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence ◽  
High Definition ◽  
Corneal Epithelial ◽  
Epithelial Thickness ◽  
Corneal Epithelial Thickness ◽  
Healthy Eyes

scholarly journals A pre-test post-test assessment of non-invasive keratograph break up time and corneal epithelial thickness after vaping

1970 ◽  
Vol 19 (4) ◽  
pp. 2926-2933 ◽  
Author(s):  
Alvin Munsamy ◽  
Bhavna Bhanprakash ◽  
Amina Sirkhot ◽  
Lufun Mlambo ◽  
Samukelisiwe Dlamuka ◽  
...  
Keyword(s):  
Electronic Cigarettes ◽  
Cigarette Use ◽  
Corneal Epithelial ◽  
Non Invasive ◽  
Epithelial Thickness ◽  
Test Assessment ◽  
Post Test ◽  
Corneal Epithelial Thickness ◽  
Break Up ◽  
The Impact

Background: The effects of electronic cigarettes on the ocular surface has yet to be shown. The purpose of the study was to assess the impact of e-cigarette use on the anterior corneal surface integrity.Methods: Forty three males and 21 females with an average of 21years were required to vape 0.05ml of e-liquid of 8mg nicotine concentration. Corneal epithelial thickness (CET) and Non Invasive Keratograph Tear Break up Time (NIKBUT) measurements were obtained prior to and post vaping. The Optovue iVue optical coherence topographer was used to measure central; superior; inferior; nasal and temporal CET and NIKBUT was assessed using the Oculus Keratograph 5M.Results: There was a mean increase for central corneal epithelial thickness of 0.3448 microns. The superior CET increased by 0.2414 microns. The inferior CET increased by 0.2931microns. The nasal CET increased by 0.2069 microns. The temporal CET increased by 0.2759 microns. The mean change in NIKBUT post-vaping was an increase of 1.40 seconds. All observations occurred at p > 0.05.Conclusion: The acute effect of e-cigarette use does not impact corneal epithelial thickness and non-invasive keratography tear break up time after 10 puffs mild exposure but more research is needed to assess if this remains the case with more frequent, higher exposure.Keywords: Pre-test post-test assessment, non-invasive keratograph breakup time, corneal epithelial thickness, vaping.

scholarly journals Assessment of Corneal Epithelial Thickness in Dry Eye Patients

2014 ◽  
Vol 91 (12) ◽  
pp. 1446-1454 ◽  
Author(s):  
Xinhan Cui ◽  
Jiaxu Hong ◽  
Fei Wang ◽  
Sophie X. Deng ◽  
Yujing Yang ◽  
...  
Keyword(s):  
Dry Eye ◽  
Corneal Epithelial ◽  
Epithelial Thickness ◽  
Corneal Epithelial Thickness
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