scholarly journals Application of the human estrogen receptor within a synthetic transcription factor in Trichoderma reesei

2020 ◽  
Vol 7 (1) ◽  
Author(s):  
Christian Derntl ◽  
Robert Mach ◽  
Astrid Mach-Aigner
2007 ◽  
Vol 313 (8) ◽  
pp. 1548-1560 ◽  
Author(s):  
Elisabetta Lambertini ◽  
Letizia Penolazzi ◽  
Elisa Tavanti ◽  
Gian Pietro Schincaglia ◽  
Margherita Zennaro ◽  
...  

2002 ◽  
Vol 80 (3) ◽  
pp. 335-341 ◽  
Author(s):  
Laura L Hart ◽  
James R Davie

The human estrogen receptor is a steroid nuclear receptor found in breast cancer and a variety of other tissues. Located in the nucleus, it can exist either loosely or tightly associated with the nuclear matrix depending on whether or not it is bound to ligand. When bound to ligand, it is responsible for the transcriptional regulation of estrogen-responsive genes through recruitment of coactivators and corepressors of transcription. The estrogen receptor is also capable of ligand-independent transcriptional activation via the mitogen-activated protein kinase pathway. Ligands have been implicated in the regulation of estrogen receptor levels via changing the levels and stability of estrogen receptor mRNA and protein. The resulting levels of estrogen receptor and the type of ligand bound to it have a direct impact on the transcription of estrogen-responsive genes.Key words: estrogen receptor, transcription factor, mitogen-activated protein kinase, MAPK, estrogen-responsive genes.


2004 ◽  
Vol 10 (12) ◽  
pp. 853-860 ◽  
Author(s):  
Martin K. Oehler ◽  
Holger Greschik ◽  
Dagmar-C. Fischer ◽  
Xiaowen Tong ◽  
Roland Schuele ◽  
...  

1995 ◽  
Vol 52 (2) ◽  
pp. 159-171 ◽  
Author(s):  
Steven F. Arnold ◽  
John D. Obourn ◽  
Matthew R. Yudt ◽  
Timothy H. Carter ◽  
Angelo C. Notides

Science ◽  
1999 ◽  
Vol 285 (5428) ◽  
pp. 744-746 ◽  
Author(s):  
J. D. Norris

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