scholarly journals Laparoscopic distal pancreatectomy for metastatic melanoma originating from the choroidal membrane: a case report

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Shigeaki Baba ◽  
Yuji Akiyama ◽  
Fumitaka Endo ◽  
Haruka Nikai ◽  
Ryo Sugimoto ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Malignant Melanoma ◽  
Metastatic Melanoma ◽  
Distal Pancreatectomy ◽  
Heavy Particle ◽  
Posterior Wall ◽  
Laparoscopic Distal Pancreatectomy ◽  
Particle Therapy ◽  
Pancreatic Metastasis ◽  
Term Survival

Abstract Background Metastatic melanoma originating from the choroidal membrane is extremely rare. Here, we report a case of laparoscopic distal pancreatectomy for malignant melanoma that developed after heavy-particle therapy for malignant choroidal melanoma. Case presentation A 43-year-old Japanese woman underwent 70 Gy heavy-particle radiotherapy for a right choroidal malignant melanoma. Positron emission tomography-computed tomography examination was performed 4 years after treatment, when contrast accumulation was observed on the posterior wall of the stomach. Endoscopic ultrasonography and computed tomography showed a mass with contrast enhancement in contact with the stomach wall. Based on the imaging findings, a gastrointestinal stromal tumor of the posterior wall of the lower gastric corpus with extramural growth was suspected. Laparoscopic surgery was performed under general anesthesia. A black-pigmented tumor originating from the pancreas was discovered. Following an intraoperative diagnosis of metastasis of malignant melanoma, a laparoscopic distal pancreatectomy was performed. The pathological diagnosis was pancreatic metastasis of malignant melanoma. The patient was treated with adjuvant immune checkpoint inhibitors and chemotherapy after surgery, which led to long-term survival. Conclusions Including this case, only eight case reports on pancreatic resection for metastatic ocular malignant melanoma have been reported. The ocular malignant melanoma with distant metastasis has a poor prognosis. Therefore, in our case, careful follow-up is required. A single pancreatic metastasis from a malignant melanoma of the choroid can be successfully managed by laparoscopic radical resection of the pancreas, and molecularly targeted adjuvant chemotherapy.

scholarly journals Primary giant aggressive amelanotic duodenal melanoma

2017 ◽  
Vol 99 (5) ◽  
pp. e131-e134 ◽  
Author(s):  
R Kilambi ◽  
AN Singh ◽  
NR Dash ◽  
KS Madhusudhan ◽  
P Das
Keyword(s):  
Computed Tomography ◽  
Malignant Melanoma ◽  
Postoperative Recovery ◽  
Amelanotic Melanoma ◽  
Whole Body ◽  
Duodenal Wall ◽  
Upper Gastrointestinal Endoscopy ◽  
Whole Body Imaging ◽  
Term Survival ◽  
Operative Specimen

Primary malignant melanoma of the gastrointestinal tract is extremely rare. A 35-year-old man presented with complaints of abdominal pain and weight loss. Contrast enhanced computed tomography showed a large mass involving the duodenum and the superior mesenteric vessels. Upper gastrointestinal endoscopy demonstrated a large, friable mass along the duodenal wall and biopsy was suggestive of malignant melanoma. A detailed physical examination and whole body imaging (positron emission tomography and computed tomography) did not reveal any other lesion. The patient underwent a pancreaticoduodenectomy with segmental resection and anastomosis of the superior mesenteric vein as well as a segmental colectomy. His postoperative recovery was uneventful. The histopathology of the operative specimen showed a malignant amelanotic melanoma arising from the duodenum with lymph nodal involvement. He received oral temozolomide. However, he developed liver metastasis at six months and again at ten months, which was managed with radiofrequency ablation both times. He is doing well at 32 months of follow-up review. Multimodality treatment including surgery, adjuvant chemotherapy and salvage therapy appears to be a promising tool for achieving long-term survival in such patients.

scholarly journals A case of laparoscopic distal pancreatectomy for pancreatic metastasis from small cell carcinoma of the lung

Suizo ◽  
2015 ◽  
Vol 30 (5) ◽  
pp. 712-719
Author(s):  
Yukiyasu OKAMURA ◽  
Masanori TOKUNAGA ◽  
Ryo ASHIDA ◽  
Yusuke YAMAMOTO ◽  
Takaaki ITO ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Distal Pancreatectomy ◽  
Small Cell Carcinoma ◽  
Laparoscopic Distal Pancreatectomy ◽  
Small Cell ◽  
Pancreatic Metastasis

scholarly journals A Case of Laparoscopic Distal Pancreatectomy for Metachoronous Pancreatic Metastasis from Renal Cell Carcinoma

2019 ◽  
Vol 80 (5) ◽  
pp. 983-989 ◽  
Author(s):  
Tetsuji WAKABAYASHI ◽  
Tsuneyuki UCHIDA ◽  
Hideyuki OYAMA ◽  
Toshimitsu SHIOZAWA ◽  
Gaku KIGAWA ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Distal Pancreatectomy ◽  
Renal Cell ◽  
Laparoscopic Distal Pancreatectomy ◽  
Pancreatic Metastasis

scholarly journals Metastatic melanoma causing recurrent intussusception and perforation of small bowel: case reports and literature review

2021 ◽  
Vol 8 (1) ◽  
pp. MMT54
Author(s):  
Yusuf Yagmur ◽  
Mehmet Ali Açıkgöz
Keyword(s):  
Computed Tomography ◽  
Abdominal Pain ◽  
Malignant Melanoma ◽  
Small Bowel ◽  
Metastatic Melanoma ◽  
Case Reports ◽  
Pain Abdomen ◽  
Free Air ◽  
Recurrent Intussusception ◽  
Short Time

Aim: To present cases of recurred jejuno-jejunal intussusception and jejunal perforation due to melanoma. Materials & methods: Case 1: A 43-year-old male under treatment for malignant melanoma was presented with abdominal pain and distention. Ten centimeter intussuscepted jejunum was resected. Second exploration was done due to failure to pass gas and stool. The reintussusception was detected and resection of reintussuscepted jejunum was performed. Case 2: A 63-year-old male was presented with abdominal pain. Abdomen computed tomography showed free air in the abdomen suggesting intestinal perforations. Perforated area at 80 cm in the jejunum sutured. Conclusion: We present the seemingly first report of reintussusception of resected segment in a very short time. Surgeons should be aware of both intussusception and perforation in metastatic melanoma.

scholarly journals Laparoscopic Distal Pancreatectomy for Insulinoma

2019 ◽  
Vol 3 (1) ◽  
Keyword(s):  
Laparoscopic Surgery ◽  
Distal Pancreatectomy ◽  
Operation Time ◽  
Severe Hypoglycemia ◽  
Laparoscopic Distal Pancreatectomy ◽  
Type I ◽  
Recurrence Rates ◽  
Pancreatic Islet Cell ◽  
Term Survival ◽  
Operative Care

Insulinomas are benign neuroendocrine tumors which are the most common of the pancreatic islet cell tumors, yet they remain a rarity. The incidence is 1-4 cases in one million patients a year. 60% are woman with a median age at presentation of 47 years. 90% are solitary and 10% multiple. More than 90% are benign adenomas and about 5%-6% of cases are malignant, and 5%-8% are associated with multiple endocrine neoplasms (MEN type I). Most insulinoma are 1-3 cm in size. Hyperinsulinism causes severe hypoglycemia and leads convulsion, depression and coma. Initial operation is curative in 88%, and long-term survival is normal. Recurrence rates of 7% (sporadic) and 21% (MEN type I) have been reported at 20 years. Clinical manifestation related with endogenous hyperinsulinism: autonomic (less specific) like sweat, worried, tremble, nausea, hungry palpitation and tingling. The more specific neuroglycopenic are confusion, changes of behavior, dizzy, headache, and weakness. The classic diagnostic criteria (Whipple’s triad): hypoglycemic symptoms, fasting hypoglycemic (< 45 mg/dL) and reversal of changes with glucose. The treatment is surgical, except in advanced metastatic disease, where streptozotocin is helpful. Enucleation is performed for solitary insulinoma, and pancreas resection is performed for multiple insulinomas. Sometimes ultrasonography intra operative is useful to determine the insulinoma location. The surgical can be done by laparotomy or laparoscopic surgery. The benefit of laparoscopic surgery is small incisions, less pain, faster mobilization, short hospitalization and better cosmetic. In the other side, laparoscopic pancreatectomy should be done by experience surgeon with availability of supporting instruments. We report a case insulinoma in 39 years old woman. The locations were in body and tail pancreas. Laparoscopic distal pancreatectomy with spleen preservation is done successfully. The operation time was 3, 5 hours. Post-operative care in ICU for one day. We start enteral nutrition in the third day post-operative and the patient may leave hospital in the fifth day post-operative.

scholarly journals A Case of Laparoscopic Distal Pancreatectomy for Metachronous Pancreatic Metastasis from Lung Cancer

2014 ◽  
Vol 47 (1) ◽  
pp. 49-56
Author(s):  
Yukinari Tokoro ◽  
Tsukasa Takayashiki ◽  
Shintaro Maeda ◽  
Hideyuki Yoshitomi ◽  
Hiroaki Shimizu ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Distal Pancreatectomy ◽  
Laparoscopic Distal Pancreatectomy ◽  
Pancreatic Metastasis

scholarly journals Is laparoscopic distal pancreatectomy decreasing morbidity? A multicentre study (ERPANDIS)

HPB ◽  
2020 ◽  
Vol 22 ◽  
pp. S305-S306
Author(s):  
M. Serradilla ◽  
J.V. Del Río ◽  
F. Rotellar ◽  
L. Sabater ◽  
A. Manuel ◽  
...  
Keyword(s):  
Multicentre Study ◽  
Distal Pancreatectomy ◽  
Laparoscopic Distal Pancreatectomy
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