scholarly journals Utilization of isoniazid prophylaxis therapy and its associated factors among HIV positive clients taking antiretroviral therapy at Fre Semaetat primary hospital, Hawzien districts, Tigrai, Northern Ethiopia

Author(s):  
Haftom Legese ◽  
Hagos Degefa ◽  
Aderajew Gebrewahd ◽  
Haftay Gebremedhin
2020 ◽  
Vol Volume 14 ◽  
pp. 1585-1594
Author(s):  
Abraham Aregay Desta ◽  
Kibriti Mehari Kidane ◽  
Ataklti Gebretsadik Woldegebriel ◽  
Kiros Fenta Ajemu ◽  
Asfawosen Aregay Berhe ◽  
...  

2020 ◽  
Author(s):  
Eyob Araya Gebrekidan ◽  
Alehegn Bishaw Geremew ◽  
Telake Azale Bisetegn

Abstract Background: Antiretroviral therapy scales up globally and in Ethiopia, as a result, AIDS-related mortality has reduced, but the number of new HIV infections increasing. Antiretroviral therapy in Ethiopia gives a chance of living longer for reproductive-age women. Prevention of pregnancy among HIV positive women is the second WHO prongs of HIV transmission with respecting women’s reproductive rights. Antiretroviral therapy uses improve the health of HIV positive women using and women's fertility desire increasing. Therefore this study aimed to assess the fertility desire and associated factors among ART user reproductive-age women. Methods: A facility-based cross-sectional study design conducted from November 2-30/2018. The calculated sample size was 400 and study participants were selected by using systematic random sampling. A pre-tested structured questionnaire was used to collect data. A binary logistic regression model was employed and adjusted odds ratio with a 95% confidence interval used to consider statistically significant Results: A total of 397 clients were participated in the study, giving a response rate of 99.3%. The proportion of fertility desire in this study was 55.2 %(95% CI, 50.4%- 60.2%). A duration of marriage < 4 year [AOR=6.9(95 CI: 1.65, 28.81)], and 5–9 years duration of marriage [AOR= 13.8 (95% CI: 2.39, 80.39)] higher as compared to 15 years and above, family influence 3.4 times more likely to have fertility desire than have no family influence [AOR= 3.4 (95% CI: 1.06, 11.25)], partner desire 4.3 times more likely have had fertility desires as compared to with counterpart [AOR= 4.3 (95% CI: 1.93,9.41)], and discussion with health care provider 66 % less likely to have fertility desire as compared with counterpart [AOR = 0.34 (95% CI: 0.39, 3.31)]. Conclusion: In this study, we have identified a high proportion of fertility desire among ART user reproductive-age women. The duration of marital status, partner influence, family influence, and discussion of health care were associated with fertility desire. Family-oriented counseling, partner involvement on reproductive health services should be encouraged to support the rights of all women to safely achieve their fertility. Keywords: Fertility desire, reproductive age, women on ART.


2020 ◽  
Vol 78 (1) ◽  
Author(s):  
Tsegu Hailu Gebru ◽  
Haftea Hagos Mekonen ◽  
Kbrom Gemechu Kiros

Abstract Background Undernutrition and HIV/AIDS are highly prevalent in sub-Saharan Africa, Ethiopia inclusive as linked in a vicious cycle. Thus, several studies have documented that undernutrition among HIV/AIDS patients increases the risk of mortality, decrease survival rates, affect the overall clinical outcome and quality of life. Despite this fact, information about the burden of undernutrition and associated factors among adults receiving antiretroviral therapy is lacking in the particular study area. Hence, this study aimed to examine the prevalence of undernutrition and associated factors among adult HIV/AIADS patients receiving antiretroviral therapy patients in Eastern Zone of Tigray, Northern Ethiopia. Methods A cross-sectional research design was adopted in data collection while systematic sampling technique was employed to sample and select the study subjects. A structured questionnaire was used to collect information from 394 study subjects through face to face method. Also, data on demographics, laboratory and anthropometric variables were collected from each selected patients sampled. The data collected were entered and analyzed using SPSS version 22.. Bivariate and multivariable logistic regression analysis with 95% confidence interval were used to find factors associated with undernutrition. The adjusted odds ratio was calculated to show the strength of the association. Variables with p-value of < 0.05 were considered statically significant. Results The mean age of the respondents was 41 (± 10). Out of 394 study respondents, about 42.9% of them were undernourished (95% CI: 37.8–47.7). Respondents who had CD4+ count less than 200 cells/μl (AOR = 1.84; 95% CI: 1–3.36), being advanced clinical staging (AOR = 3.6; 95% CI: 2.11–6.18), and not taking co-trimoxazole preventive therapy (AOR = 2.38; 95% CI: 1.21–4.6) were independently associated with undernutrition. Conclusion The result of this study indicated that the prevalence of undernutrition was high. Respondents with advanced clinical stage of CD4+ count less than 200 cells/ul and those that were not taking co-trimoxazole preventive therapy was found to be positively associated with undernutrition. Therefore, the implementation of nutritional programs is very crucial to improve the nutritional status of HIV/AIDS patients in the particular study.


2020 ◽  
Vol 10 ◽  
pp. 2235042X1989931
Author(s):  
Zenebework Getahun ◽  
Muluken Azage ◽  
Taye Abuhay ◽  
Fantu Abebe

Background: People living with human immunodeficiency virus (HIV) are facing an increased burden of noncommunicable diseases (NCDs) comorbidity. There is, however, paucity of information on the magnitude of HIV-NCDs comorbidity, its associated factors, and how the health system is responding to the double burden in Ethiopia. Objective: To determine the magnitude of comorbidity between HIV and hypertension or diabetes and associated factors among HIV-positive adults receiving antiretroviral therapy (ART) in Bahir Dar city, Ethiopia. Methods: A facility-based cross-sectional study was conducted among 560 randomly selected HIV-positive adults taking ART. Data were collected using a structured questionnaire and analyzed using SPSS version 23. Descriptive statistics were used to describe the data. A logistic regression model was fit to identify associated factors with comorbidity of HIV and NCDs. Results: The magnitude of comorbidity was 19.6% (95% confidence interval (CI): 16.0–23.0). Being older (55 and above years) adjusted odds ratio (AOR: 8.5; 95% CI: 3.2–15.1), taking second-line ART regimen containing tenofovir (AOR: 2.7; 95% CI: 1.3–5.6), and increased body mass index (BMI) ≥25 (AOR: 2.7; 95% CI: 1.2–6.5) were the factors associated with comorbidity. Participants reported that they were not managed in an integrated and coordinated manner. Conclusions: The magnitude of comorbidity among adults was high in the study area. Being older, second-line ART regimen and high BMI ≥25 increased the odds of having NCDs among HIV-positive adults. Targeted screening for the incidences of NCDs, addressing modifiable risk factors, and providing integrated care would help to improve the quality of life comorbid patients.


2020 ◽  
Vol Volume 12 ◽  
pp. 687-695
Author(s):  
Gebremedhin Gebreegziabher Gebretsadik ◽  
Hailay Gebretnsae ◽  
Mulu Ftwi ◽  
Afewerki Tesfahunegn Nigusse

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Dawit Jember Tesfaye ◽  
Desalegn Tsegaw Hibistu ◽  
Teshome Abuka Abebo ◽  
Feleke Tafesse Asfaw ◽  
Kaleegziabher Lukas ◽  
...  

2020 ◽  
Vol 8 ◽  
pp. 205031212090607
Author(s):  
Rahel Feleke ◽  
Biftu Geda ◽  
Kedir Teji Roba ◽  
Fitsum Weldegebreal

Background: Antiretroviral treatment failure occurred when the antiretroviral regimen is unable to control HIV infection. There is no information on antiretroviral therapy failure in this study area. Objective: The aim of this study was to assess the magnitude and associated factors of antiretroviral therapy failure among HIV-positive adult patients in Harar public hospitals from January to February 2018. Methods: An institution-based cross-sectional study was conducted using chart review data from February 2005 to July 2017. Systematic sampling technique was used to include a sample of 1094 patient charts. Data were analyzed by Statistical Package for Social Sciences version 20.0. Statistical significance was considered at p < 0.05. Results: The prevalence of first-line antiretroviral treatment failure was 21% (95% confidence interval = 18.3–23.5). Being male in sex, age of 45–54 years, patients with World Health Organization stages 3 and 4 during antiretroviral therapy initiation, a baseline CD4 count <100 cells/mm3, poor drug adherence, and on antiretroviral therapy follow-up for ⩾25 months were predictors of antiretroviral treatment failure. Conclusion: In this study, the rate of antiretroviral treatment failure is relatively high. Therefore, the concerned body should pay attention to the predictors to reduce the risk of treatment failure among this study group.


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