scholarly journals Ophthalmic artery chemosurgery for retinoblastoma: an initial 3-year experience from two major institutes in Egypt

2020 ◽  
Vol 51 (1) ◽  
Author(s):  
Moustafa H Othman ◽  
Farouk Hassan ◽  
Hamdy M Ibrahim ◽  
Eman Aboelhamd Ahmed ◽  
George Yassa ◽  
...  
Keyword(s):  
Ophthalmic Artery

Contralateral catheterization of the ophthalmic artery to deliver intra-arterial chemotherapy in retinoblastoma

2021 ◽  
pp. 197140092110246
Author(s):  
Giancarlo Saal-Zapata ◽  
Rodolfo Rodríguez ◽  
Aaron Rodriguez-Calienes ◽  
Raúl Cordero
Keyword(s):  
Ophthalmic Artery ◽  
Internal Carotid ◽  
Pediatric Population ◽  
Anterior Communicating Artery ◽  
Chemotherapeutic Drugs ◽  
First Line ◽  
Chemotherapy Administration ◽  
Class D ◽  
Severity Of The Disease ◽  
Cure Rates

Retinoblastoma is the most frequent ocular malignancy in the pediatric population and intra-arterial chemotherapy has emerged as the first-line treatment of this entity with cure rates ranging from 33–100%, depending on the severity of the disease. We present the case of an advanced retinoblastoma in a pediatric patient who underwent intra-arterial chemotherapy through a contralateral route due to unsuccessful catheterization of the ophthalmic artery. The patient was diagnosed with a class D retinoblastoma which underwent the catheterization of the ophthalmic artery through the contralateral internal carotid and through the anterior communicating artery. In this case, intra-arterial chemotherapy administration was successfully delivered without complications. Contralateral routes for intra-arterial chemotherapy are safe and allow adequate penetration of the chemotherapeutic drugs in cases where a well-developed anterior communicating artery is present.

scholarly journals Risk factors for ophthalmic artery stenosis and occlusion in patients with retinoblastoma treated with intra-arterial chemotherapy

2021 ◽  
pp. bjophthalmol-2021-319118
Author(s):  
Min Zhou ◽  
Xuyang Wen ◽  
Shichong Jia ◽  
Yanping Han ◽  
Xiaoyu He ◽  
...  
Keyword(s):  
Risk Factors ◽  
Ophthalmic Artery ◽  
Cox Regression ◽  
Median Number ◽  
Disease Stage ◽  
Orifice Diameter ◽  
Clinical Predictors ◽  
Total Incidence ◽  
Intraocular Retinoblastoma ◽  
Stenosis And Occlusion

PurposeTo explore the risk factors for ophthalmic artery (OA) stenosis and occlusion after intra-arterial chemotherapy (IAC) with selective ophthalmic artery catheterisation (OAC) in the treatment of retinoblastoma.DesignRetrospective, single centre case-control study.MethodsThe study was conducted including consecutive patients with unilateral or bilateral intraocular retinoblastoma undergoing IAC between June 2016 and June 2019 with a follow-up time of 4 years. Main outcomes are rate of IAC-induced OA occlusion and OA diameter.Results346 attempted OAC infusions were successful. The total incidence of OA occlusion was 15.89%. The occlusion and control groups were similar in patients’ age, sex and disease stage. Median OA diameter was 0.49 mm in those with OA occlusion, and 0.66 mm in those without occlusion. In the occlusion group, the OA diameter difference was significantly larger between the first IAC and the final IAC (0.22mm vs 0.12mm, p=0.001). In both groups, the median number of IAC treatments was 3. Multivariate Cox regression models included initial OA diameter (OR: 0.005, p=0.001), ratio of OA orifice diameter differences between first and last IAC to the initial OA orifice diameter (OR: 4.661, p=0.003), and number of IAC (OR: 1.538, p=0.042) as clinical features significantly associated with OA occlusion.ConclusionsThe OA diameter at first IAC treatment, the ratio of OA orifice diameter differences between first and last IAC to the initial OA orifice diameter and total number of IAC treatments may be three main clinical predictors for OA occlusion after IAC for retinoblastoma.

Selective Ophthalmic artery chemotherapy with melphalan in the management of unilateral retinoblastoma: a prospective study

2021 ◽  
Author(s):  
Livia Lumbroso-Le Rouic ◽  
Raphaël Blanc ◽  
Caroline Saint Martin ◽  
Alexia Savignoni ◽  
Hervé J. Brisse ◽  
...  
Keyword(s):  
Prospective Study ◽  
Ophthalmic Artery ◽  
A Prospective Study

Prospective analysis of serious cardiorespiratory events in children during ophthalmic artery chemotherapy for retinoblastoma under a deep standardized anesthesia

2017 ◽  
Vol 28 (2) ◽  
pp. 120-126 ◽  
Author(s):  
Marie-Claire Nghe ◽  
Anne Godier ◽  
Anoushée Shaffii ◽  
Isabelle Leblanc ◽  
Hervé Picard ◽  
...  
Keyword(s):  
Ophthalmic Artery ◽  
Prospective Analysis
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