scholarly journals The value of double inversion recovery MRI sequence in assessment of epilepsy patients

Author(s):  
Mohamed Abdelbar Abdelmaksoud Aly ◽  
Tarek Mohamed Saleh ◽  
Amr Mohamed Ahmed Elfatatry ◽  
Moataz Mohamed Montasser

Abstract Background The double inversion recovery (DIR) pulse sequence was introduced several years ago and since that it grew important value in clinical neuroimaging. We aimed to assess the added value of double inversion recovery in evaluation of epileptic patients. Results In mesial temporal sclerosis, the measured contrast parameters (SNR, CR, CNR and AI) were found to be significantly higher in DIR than in FLAIR and T2 sequences. In cases of focal cortical dysplasia, significantly higher CNR and AI in DIR than in T2 and FLAIR. Also DIR showed higher detection of the increased cortical thickness and cortical signal intensity than the T2 and FLAIR sequences. In tuberous sclerosis cases, the DIR showed higher visibility of the lesions than the T2 and FLAIR. Also DIR showed higher ability to detected grey-white matters junction blurring. Conclusions Our study concluded that the greatest value of the double inversion recovery sequence is its higher ability in detecting multiple characteristics of the lesions in a one sequence.

2016 ◽  
Vol 61 ◽  
pp. 87-93 ◽  
Author(s):  
Lily C. Wong-Kisiel ◽  
Jeffrey W. Britton ◽  
Robert J. Witte ◽  
Kristen M. Kelly-Williams ◽  
Amy L. Kotsenas ◽  
...  

2017 ◽  
Vol 30 (4) ◽  
pp. 352-355 ◽  
Author(s):  
Domenico S Zimatore ◽  
Mirko Trentadue ◽  
Marco Castellaro ◽  
Monica Ferlisi ◽  
Enrico Piovan ◽  
...  

In epileptic patients with multiple sclerosis (MS), cortical lesions have been suggested to cause seizures. In brain magnetic resonance imaging (MRI), double inversion recovery (DIR) sequences are generally used to evaluate MS cortical disease burden. We present the case of a woman, diagnosed with MS, suffering from drug-resistant partial seizures initially attributed to MS. The patient underwent many MRI exams, but only by means of high-resolution three-dimensional DIR sequences was a focal cortical dysplasia discovered. The MRI findings and FDG-PET/CT supported the diagnosis. This case recommends the use of DIR sequences both in patients with suspect epileptogenic lesions not detected with routine MRI protocols and in epileptic patient with MS, before ascribing seizures to MS.


Epilepsia ◽  
2001 ◽  
Vol 42 (s6) ◽  
pp. 37-41 ◽  
Author(s):  
Shigeki Kameyama ◽  
Masafumi Fukuda ◽  
Masaru Tomikawa ◽  
Nobuhito Morota ◽  
Makoto Oishi ◽  
...  

Epilepsia ◽  
2008 ◽  
Vol 42 ◽  
pp. 37-41 ◽  
Author(s):  
Shigeki Kameyama ◽  
Masafumi Fukuda ◽  
Masaru Tomikawa ◽  
Nobuhito Morota ◽  
Makoto Oishi ◽  
...  

2014 ◽  
Vol 16 (4) ◽  
pp. 533-539 ◽  
Author(s):  
Nobutaka Mukae ◽  
Satoshi O Suzuki ◽  
Takato Morioka ◽  
Nobuya Murakami ◽  
Kimiaki Hashiguchi ◽  
...  

2021 ◽  
Author(s):  
Horst Urbach ◽  
Elias Kellner ◽  
Nico Kremers ◽  
Ingmar Blümcke ◽  
Theo Demerath

AbstractFocal cortical dysplasia (FCD) are histopathologically categorized in ILAE type I to III. Mild malformations of cortical development (mMCD) including those with oligodendroglial hyperplasia (MOGHE) are to be integrated into this classification yet. Only FCD type II have distinctive MRI and molecular genetics alterations so far. Subtle FCD including FCD type II located in the depth of a sulcus are often overlooked requiring the use of dedicated sequences (MP2RAGE, FLAWS, EDGE) and/or voxel (VBM)- or surface-based (SBM) postprocessing. The added value of 7 Tesla MRI has to be proven yet.


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