Age-associated alterations in the recruitment of signal-transduction proteins to lipid rafts in human T lymphocytes

2003 ◽  
Vol 75 (2) ◽  
pp. 373-381 ◽  
Author(s):  
Anis Larbi ◽  
Nadine Douziech ◽  
Gilles Dupuis ◽  
Abdelouahed Khalil ◽  
Hugues Pelletier ◽  
...  
Keyword(s):  
Signal Transduction ◽  
T Lymphocytes ◽  
Lipid Rafts ◽  
Human T Lymphocytes ◽  
Signal Transduction Proteins

Signal Transduction in Human T Lymphocytes

1987 ◽  
Vol 95 (1) ◽  
pp. 137-159 ◽  
Author(s):  
David C. Linch ◽  
Diana L. Wallace ◽  
Kieran O'Flynn
Keyword(s):  
Signal Transduction ◽  
T Lymphocytes ◽  
Human T Lymphocytes

FK-506 and cyclosporin A inhibit highly similar signal transduction pathways in human T lymphocytes

1991 ◽  
Vol 133 (2) ◽  
pp. 269-284 ◽  
Author(s):  
C.Shirley Lin ◽  
Robert C. Boltz ◽  
John J. Siekierka ◽  
Nolan H. Sigal
Keyword(s):  
Signal Transduction ◽  
T Lymphocytes ◽  
Cyclosporin A ◽  
Signal Transduction Pathways ◽  
Fk 506 ◽  
Human T Lymphocytes

scholarly journals Signal transduction in primary human T lymphocytes in altered gravity – results of the MASER-12 suborbital space flight mission

2013 ◽  
Vol 11 (1) ◽  
pp. 32 ◽  
Author(s):  
Svantje Tauber ◽  
Swantje Hauschild ◽  
Claudia Crescio ◽  
Christian Secchi ◽  
Katrin Paulsen ◽  
...  
Keyword(s):  
Signal Transduction ◽  
T Lymphocytes ◽  
Space Flight ◽  
Altered Gravity ◽  
Human T Lymphocytes

Differential role of lipid rafts in the functions of CD4+ and CD8+ human T lymphocytes with aging

2006 ◽  
Vol 18 (7) ◽  
pp. 1017-1030 ◽  
Author(s):  
Anis Larbi ◽  
Gilles Dupuis ◽  
Abdelouahed Khalil ◽  
Nadine Douziech ◽  
Carl Fortin ◽  
...  
Keyword(s):  
T Lymphocytes ◽  
Lipid Rafts ◽  
Human T Lymphocytes

Effect of the opioid methionine enkephalinamide on signal transduction in human T-lymphocytes

Life Sciences ◽  
1998 ◽  
Vol 62 (14) ◽  
pp. 1251-1259 ◽  
Author(s):  
Anja Nørbæk Sørensen ◽  
Mogens H. Claësson
Keyword(s):  
Signal Transduction ◽  
T Lymphocytes ◽  
Human T Lymphocytes

Dietary zinc deficiency and expression of T lymphocyte signal transduction proteins

2000 ◽  
Vol 78 (10) ◽  
pp. 823-828 ◽  
Author(s):  
Carla G Taylor ◽  
Jeri-Anne C Giesbrecht
Keyword(s):  
Signal Transduction ◽  
T Lymphocytes ◽  
Immune Function ◽  
T Lymphocyte ◽  
Molecular Level ◽  
Immune Dysfunction ◽  
Zn Deficiency ◽  
Dietary Zinc ◽  
Signal Transduction Proteins

Impaired immune function in dietary zinc (Zn) deficiency is characterized in part by reduced lymphocyte numbers (lymphopenia) and depressed cell-mediated (T lymphocyte) immune function, however, the causative mechanisms at the molecular level have not been elucidated. This paper will focus on the role of dietary Zn in T lymphocyte signal transduction, and specifically, the early Zn-dependent steps for phosphorylation and the putative Zn-finger proteins or Zn-metalloenzymes that may be part of the molecular mechanism for explaining immune dysfunction in Zn deficiency. One of the major recent findings is that murine splenic T lymphocyte p56lck expression is elevated in dietary Zn deficiency and caloric deficiency. Based on the known functions of p56lck, it is proposed that elevated p56lck may contribute to altered thymocyte maturation, apoptosis, and lymphopenia in dietary Zn deficiency and other malnutrition syndromes.Key words: zinc, T lymphocytes, signal transduction, immune function.

scholarly journals CD28 and Lipid Rafts Coordinate Recruitment of Lck to the Immunological Synapse of Human T Lymphocytes

2004 ◽  
Vol 173 (9) ◽  
pp. 5392-5397 ◽  
Author(s):  
Regina Tavano ◽  
Giorgia Gri ◽  
Barbara Molon ◽  
Barbara Marinari ◽  
Christopher E. Rudd ◽  
...  
Keyword(s):  
T Lymphocytes ◽  
Lipid Rafts ◽  
Immunological Synapse ◽  
Human T Lymphocytes
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