scholarly journals Transcranial magnetic stimulation in clinical practice

2016 ◽  
Vol 22 (6) ◽  
pp. 373-379 ◽  
Author(s):  
Sheila Hardy ◽  
Lorraine Bastick ◽  
Alex O'Neill-Kerr ◽  
Priyadharshini Sabesan ◽  
Sudheer Lankappa ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Transcranial Magnetic Stimulation ◽  
Magnetic Stimulation ◽  
Clinical Depression ◽  
Adult Patients

SummaryUp to 40% of people with depression do not recover following standard treatments such as medication and psychotherapy. Transcranial magnetic stimulation (TMS) is a treatment used worldwide for adult patients with severe clinical depression when antidepressants have repeatedly failed to control their symptoms. This article explains the use of TMS in clinical practice.

scholarly journals La stimolazione magnetica transcranica (TMS) nella pratica clinica [translation of “Transcranial magnetic stimulation in clinical practice” by Andrea Sacchetti]

2016 ◽  
Vol 22 (6) ◽  
Author(s):  
Sheila Hardy ◽  
Lorraine Bastick ◽  
Alex O'Neill-Kerr ◽  
Priyadharshini Sabesan ◽  
Sudheer Lankappa ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Transcranial Magnetic Stimulation ◽  
Magnetic Stimulation

scholarly journals Repetitive Transcranial Magnetic Stimulation in adult patients with migraine: Report of 3 cases

2020 ◽  
Vol 13 (6) ◽  
pp. 1849
Author(s):  
José Ricardo López Melgar ◽  
Sahory Bautista ◽  
Andrea Urbina ◽  
Edgar Castillo – Armas ◽  
Erick Carrillo
Keyword(s):  
Transcranial Magnetic Stimulation ◽  
Magnetic Stimulation ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Adult Patients

Transcranial magnetic stimulation (TMS) safety: a practical guide for psychiatrists

2018 ◽  
Vol 26 (2) ◽  
pp. 189-192 ◽  
Author(s):  
Rohan Taylor ◽  
Veronica Galvez ◽  
Colleen Loo
Keyword(s):  
Older Adults ◽  
Clinical Practice ◽  
Transcranial Magnetic Stimulation ◽  
Magnetic Stimulation ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Local Pain ◽  
Safety Issues ◽  
Assessment And Monitoring ◽  
Monitoring Treatment ◽  
Site Of Stimulation

Objectives: Repetitive transcranial magnetic stimulation (rTMS) is increasingly being utilised as a treatment option for depression, and with this comes a need for a practical review of safety issues intended for clinicians. This article provides an overview of the current literature regarding safety issues with rTMS for depression, and provides recommendations for clinical practice. Conclusions: Overall, rTMS is a well-tolerated treatment with common side effects (such as headache or local pain at the site of stimulation) being mild. Severe adverse effects, such as seizures, hearing impairment or mania, are uncommon. Certain populations, including adolescents, pregnant women, older adults and those with metal/electronic implants, require special consideration when prescribing and monitoring treatment courses. With adequate assessment and monitoring processes, rTMS can be administered safely in a large proportion of depressed patients.

Rewarding Network Mechanism of Left Orbito-frontal Cortex Transcranial Magnetic Stimulation in Depression

2017 ◽  
Vol 41 (S1) ◽  
pp. S142-S143
Author(s):  
Q. Dai ◽  
Y. Xuntao ◽  
F. Zhengzhi
Keyword(s):  
Transcranial Magnetic Stimulation ◽  
Therapeutic Effect ◽  
Magnetic Stimulation ◽  
Antidepressant Treatment ◽  
Neural Mechanism ◽  
Clinical Depression ◽  
Dorsolateral Striatum ◽  
Lower Baseline ◽  
Before And After ◽  
Function Connectivity

ObjectiveThe difficulties in the clinical antidepressant treatment lead to the pursuing of more effective methods such as transcranial magnetic stimulation (TMS). Mixed findings from DLPFC targeted TMS result in the exploration of optimal stimulation location. Disturbed function of obitofrontal cortex (OFC) has been indicated in depression, which is involving in the remission of depression. However, whether it could be a more specific treating target is not tested. Simultaneously, disturbed reward network (RN) has been confirmed in depression, however, whether this could be improved by TMS treatment remains unclear.MethodsFourteen patients with major depressive disorder (MDD) were allocated in a four-week course of OFC targeted TMS. Motivated by the literature, before and after the treatment, the function connectivity of RN with the seed of ventral striatum was conducted. The results were also compared with the data from 33 healthy controls.ResultsThe OFC targeted TMS improved the clinical depression significantly and enhanced the function connectivity within the RN effectively. Specifically, lower baseline dorsolateral striatum connectivity predicted strong therapeutic effect of TMS on depression, while lower baseline insula connectivity predicted weak therapeutic effect on depression.ConclusionsThe findings offer the first experimental evidence of the therapeutic effect of OFC targeted TMS on clinical depression, enhanced function connectivity within RN might be the potential neural mechanism (Fig. 1). Lower dorsolateral striatum connection might be a reliable neural biomarker of strong responding for TMS treatment, which helps to identify the patients who will be cured by TMS most effectively.

scholarly journals Repetitive transcranial magnetic stimulation (rTMS) using different TMS instruments for major depressive disorder at a suburban tertiary clinic

2019 ◽  
Vol 11 (1) ◽  
pp. 1-8
Author(s):  
Maria Cristina Davila ◽  
Brianna Ely ◽  
Ann M. Manzardo
Keyword(s):  
Major Depressive Disorder ◽  
Clinical Practice ◽  
Transcranial Magnetic Stimulation ◽  
Depressive Disorder ◽  
Clinical Response ◽  
Magnetic Stimulation ◽  
Suicide Attempts ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Major Depressive ◽  
Remission Rates

Repetitive transcranial magnetic stimulation (rTMS) is a neurostimulatory technique used to modulate orbital frontal corticostriatal (OFC) activity and clinical symptomatology for psychiatric disorders involving OFC dysfunction. We examined the effectiveness of rTMS in the treatment of major depressive disorder in an applied clinical setting (Awakening KC CNI) to assess efficacy and optimize rTMS parameters within clinical practice. A retrospective review of medical records was carried out on patients with major depressive disorder undergoing rTMS therapy at Awakenings KC Clinical Neuroscience Institute (CNI), a suburban tertiary psychiatric clinic. A detailed de-identified data set of clinical outcomes was compiled. Patient Health Questionnaire 9 (PHQ-9) total score, clinical remission rate and week achieved were evaluated over 6 weeks of treatment to assess clinical response referencing two different rTMS instruments (MagVenture; NeuroStar). Our survey included 247 participants from males (N=98) and females (N=149) with average baseline PHQ-9 scores of 21.7±4, classified as severe depression. Clinically rated remission rates of 72% were achieved in 3.1±1.0 weeks and associated with prior history of psychiatric hospitalization, suicide attempts and substance use disorder. Average baseline PHQ-9 scores decreased significantly over time with proportionately greater remission rates achieved for patients treated using the MagVenture over NeuroStar instrument. rTMS in applied clinical practice is efficacious over a wide range of settings and patients. Clinical response was related to severity of depression symptoms (e.g., prior hospitalization; suicide attempts) validating efficacy in critically ill groups. Clinical response may be impacted by rTMS instrument, magnetic field parameters or individual factors.

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