Lymphoblastic Transformation

2021 ◽  
pp. 77-86
Author(s):  
Pauline Brousseau ◽  
Yves Payette ◽  
Helen Tryphonas ◽  
Barry Blakley ◽  
Herman Boermans ◽  
...  
Keyword(s):  
Lymphoblastic Transformation

Electron Microscopic identification of Pre-B Lymphocytes in the Bone Marrow of a Patient with Chronic Myelocytic Leukemic in Blast Crisis

1982 ◽  
Vol 40 ◽  
pp. 346-347
Author(s):  
T. Mullin ◽  
G. Yee ◽  
M. Aheam ◽  
J. Trujillo
Keyword(s):  
Blast Crisis ◽  
Immunoglobulin M ◽  
Terminal Deoxynucleotidyl Transferase ◽  
Transformation Theory ◽  
Electron Microscopic ◽  
Chemotherapeutic Sensitivity ◽  
Microscopic Studies ◽  
Hematopoietic Precursor ◽  
Lymphoblastic Transformation ◽  
B Lineage

There have been numerous reports in the current literature suggesting that hematopoietic precursor cells in some human chronic myelocytic leukemias (CML) undergo lymphoblastic transformation at the time of the acute blast crisis (BC) stage. The primary evidence offered in support of this transformation theory--lymphoblastic appearing morphology, increased terminal deoxynucleotidyl transferase (TdT) activity, and chemotherapeutic sensitivity to vincristine and prednisone--has been indirect, however, since these features may occur in nonlymphoid cells. More direct support for the Pre-B lineage of these cells has recently been provided by immunofluorescent light microscopic studies demonstrating the presence of intracytoplasmic immunoglobulin M (IgM) in these CML-BC cells.

Acute lymphoblastic transformation of essential thrombocythaemia

2008 ◽  
Vol 89 (4) ◽  
pp. 921-922 ◽  
Author(s):  
P. T. Murphy ◽  
M. Sivakumaran ◽  
F. van Rhee ◽  
A. E. WATMORE ◽  
V. E. Mitchell
Keyword(s):  
Essential Thrombocythaemia ◽  
Lymphoblastic Transformation

Acquisition of genomic events leading to lymphoblastic transformation in a rare case of myeloproliferative neoplasm withBCR-JAK2fusion transcript

2016 ◽  
Vol 97 (4) ◽  
pp. 399-402 ◽  
Author(s):  
Nicolas Duployez ◽  
Olivier Nibourel ◽  
Benoît Ducourneau ◽  
Nathalie Grardel ◽  
Thomas Boyer ◽  
...  
Keyword(s):  
Rare Case ◽  
Myeloproliferative Neoplasm ◽  
Lymphoblastic Transformation

Correlation between binding activity, inhibition of lymphoblastic transformation and metabolism of tixocortol 21 pivalate in mouse thymocytes

1987 ◽  
Vol 21 (3-4) ◽  
pp. 262-265
Author(s):  
V. Lelièvre ◽  
B. Bertin ◽  
F. Chanoine ◽  
J. Buré ◽  
J. L. Junien
Keyword(s):  
Binding Activity ◽  
Activity Inhibition ◽  
Lymphoblastic Transformation

scholarly journals Pediatric chronic myeloid leukemia with inv(3)(q21q26.2) and T lymphoblastic transformation: a case report

2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Margaret Lewen ◽  
Renee Gresh ◽  
Maria Queenan ◽  
Michele Paessler ◽  
Vinodh Pillai ◽  
...  
Keyword(s):  
Case Report ◽  
Chronic Myeloid Leukemia ◽  
Myeloid Leukemia ◽  
Lymphoblastic Transformation

Haemolytic streptococcus infection of chronic maxillary sinusitis An immunological study using the skin window test

1988 ◽  
Vol 102 (10) ◽  
pp. 890-893
Author(s):  
H. Toppozada
Keyword(s):  
Immune Response ◽  
Cellular Immune Response ◽  
Maxillary Sinusitis ◽  
Immunological Study ◽  
Haemolytic Streptococcus ◽  
Prevention And Treatment ◽  
Lymphoblastic Transformation ◽  
Chronic Maxillary Sinusitis ◽  
Cellular Immune ◽  
Nose And Throat

AbstractThe SWT was performed on 30 patients with chronic haemolytic streptococcus maxillary sinusitis, and 5 controls with no streptococcus in their nose and throat. Foreign and patient's own organism were used as antigen. The lymphoblastic transformation was higher in control streptococcus free patients than in chronic maxillary sinusitis, more when using foreign than patient's own organism. The failure of cellular immune response as a contributary factor tochronicity of maxillary sinusitis is discussed. The possible value of prepared foreign streptococcus vaccine in prevention and treatment ismentioned.

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