Calcium Phosphate Ceramics for Bone Tissue Engineering

2007 ◽  
pp. 9-1-9-18
Author(s):  
Paul Spauwen ◽  
John Jansen ◽  
P QuintenRuhé ◽  
Joop Wolke
Keyword(s):  
Tissue Engineering ◽  
Calcium Phosphate ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Calcium Phosphate Ceramics

Preparation of Porous HAW/ß-TCP Ceramics with In Situ Synthesis of HA Whiskers

2010 ◽  
Vol 434-435 ◽  
pp. 617-619
Author(s):  
Qing Feng Zan ◽  
Yao Cong Han ◽  
Li Min Dong ◽  
Chen Wang ◽  
Jie Mo Tian
Keyword(s):  
Tissue Engineering ◽  
Calcium Phosphate ◽  
Bone Tissue Engineering ◽  
Porous Materials ◽  
Bone Tissue ◽  
Phase Content ◽  
Calcium Phosphate Ceramics ◽  
Ceramics Matrix

Adding whiskers to ceramic was a way that has been used to strengthen the ceramics matrix. For porous materials, strength of pore walls was an important factor for strength of the whole materials. Porous calcium phosphate ceramics were always used as scaffolds of bone tissue engineering because of their biocompatible and osteoconductibility. In this work, HA whiskers were born in the porous -TCP ceramic during in situ procedure. The HA whiskers with about 2m for length and 100nm for diameter were observed from SEM photographs of as-fabricated porous HA ceramics, and the phase content was determined by XRD.

scholarly journals 3D Printing of Calcium Phosphate Ceramics for Bone Tissue Engineering and Drug Delivery

2016 ◽  
Vol 45 (1) ◽  
pp. 23-44 ◽  
Author(s):  
Ryan Trombetta ◽  
Jason A. Inzana ◽  
Edward M. Schwarz ◽  
Stephen L. Kates ◽  
Hani A. Awad
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Calcium Phosphate ◽  
3D Printing ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Calcium Phosphate Ceramics

scholarly journals Pro-angiogenic and osteogenic composite scaffolds of fibrin, alginate and calcium phosphate for bone tissue engineering

2021 ◽  
Vol 12 ◽  
pp. 204173142110056
Author(s):  
Nupur Kohli ◽  
Vaibhav Sharma ◽  
Alodia Orera ◽  
Prasad Sawadkar ◽  
Nazanin Owji ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Calcium Phosphate ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Chorioallantoic Membrane ◽  
Cam Assay ◽  
Clinical Model ◽  
Chick Chorioallantoic Membrane ◽  
Biomimetic Method ◽  
Alginate Scaffold

Due to the limitations of bone autografts, we aimed to develop new composite biomaterials with pro-angiogenic and osteogenic properties to be used as scaffolds in bone tissue engineering applications. We used a porous, cross-linked and slowly biodegradable fibrin/alginate scaffold originally developed in our laboratory for wound healing, throughout which deposits of calcium phosphate (CaP) were evenly incorporated using an established biomimetic method. Material characterisation revealed the porous nature and confirmed the deposition of CaP precursor phases throughout the scaffolds. MC3T3-E1 cells adhered to the scaffolds, proliferated, migrated and differentiated down the osteogenic pathway during the culture period. Chick chorioallantoic membrane (CAM) assay results showed that the scaffolds were pro-angiogenic and biocompatible. The work presented here gave useful insights into the potential of these pro-angiogenic and osteogenic scaffolds for bone tissue engineering and merits further research in a pre-clinical model prior to its clinical translation.

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