Maternal Diabetes, Large-for-Gestational-Age Births, and First Trimester Pregnancy–Associated Plasma Protein-A

2015 ◽  
Vol 100 (6) ◽  
pp. 2372-2379 ◽  
Author(s):  
George Wells ◽  
Kerrin Bleicher ◽  
Xuguang Han ◽  
Monika McShane ◽  
Yuk Fun Chan ◽  
...  
Keyword(s):  
Plasma Protein ◽  
Gestational Age ◽  
Protein A ◽  
Maternal Diabetes ◽  
First Trimester ◽  
Large For Gestational Age ◽  
First Trimester Pregnancy ◽  
Trimester Pregnancy

Low first-trimester pregnancy-associated plasma protein-A and Cornelia de Lange syndrome

2003 ◽  
Vol 23 (10) ◽  
pp. 864-864 ◽  
Author(s):  
S. Arbuzova ◽  
M. Nikolenko ◽  
D. Krantz ◽  
T. Hallahan ◽  
J. Macri
Keyword(s):  
Plasma Protein ◽  
Protein A ◽  
First Trimester ◽  
Cornelia De Lange Syndrome ◽  
First Trimester Pregnancy ◽  
Trimester Pregnancy ◽  
Cornelia De Lange

First trimester pregnancy-associated plasma protein-A in pregnancies complicated by subsequent gestational diabetes

2011 ◽  
Vol 31 (6) ◽  
pp. 523-528 ◽  
Author(s):  
Fausta Beneventi ◽  
Margherita Simonetta ◽  
Elisabetta Lovati ◽  
Giulia Albonico ◽  
Carmine Tinelli ◽  
...  
Keyword(s):  
Gestational Diabetes ◽  
Plasma Protein ◽  
Protein A ◽  
First Trimester ◽  
First Trimester Pregnancy ◽  
Trimester Pregnancy

First-trimester pregnancy associated plasma protein-A (PAPP-A) levels identify the pregnant smoker at high-risk of pregnancy complications

2005 ◽  
Vol 193 (6) ◽  
pp. S121
Author(s):  
Adam Urato (F) ◽  
Sabrina Craigo ◽  
Jamie Collins ◽  
Fergal D. Malone ◽  
T. Flint Porter ◽  
...  
Keyword(s):  
High Risk ◽  
Plasma Protein ◽  
Pregnancy Complications ◽  
Protein A ◽  
First Trimester ◽  
First Trimester Pregnancy ◽  
Trimester Pregnancy ◽  
Pregnant Smoker

scholarly journals The Relationship Between First-Trimester Aneuploidy Markers and Birth Weight

2021 ◽  
pp. 1-6
Author(s):  
Cenk Soysal ◽  
İsmail Biyik ◽  
Özlem Erten ◽  
Onur Ince ◽  
Hatice Sari ◽  
...  
Keyword(s):  
Plasma Protein ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Protein A ◽  
First Trimester ◽  
Nuchal Translucency ◽  
Maternal Serum ◽  
Large For Gestational Age ◽  
Aneuploidy Screening ◽  
Beta Human Chorionic Gonadotropin

OBJECTIVE: We aimed to determine the relationship between the first-trimester aneuploidy screeningma and the predicted weight at birth: Small for gestational age and large for gestational age. STUDY DESIGN: 594 low-risk pregnant women with a singleton pregnancy, who underwent first-trimester aneuploidy screening by measuring nuchal translucency, maternal serum free beta-human chorionic gonadotropin, and pregnancy-associated plasma protein-A were included in the study. Those weighing above the 3rd percentile and below the 10th percentile were defined as small for gestational age, and those over the 90th percentile were defined as large for gestational age. RESULTS: A total of 594 pregnant women were enrolled. The mean maternal age of the studied group was 28.8±5.5 years. Low maternal serum pregnancy-associated plasma protein-A levels and decreased nuchal translucency measurements were associated with the small for gestational age newborn (p<0.001 and p=0.001, respectively). There is a significant correlation with large for gestational age for newborns only with an increase in maternal serum pregnancy-associated plasma protein-A levels (p=0.001). beta-human chorionic gonadotropin levels were not associated with the birth weight (p=0.735). CONCLUSION: Maternal serum pregnancy-associated plasma protein-A levels, one of the markers in first-trimester aneuploidy screening, can be used in the prediction of small for gestational age and large for gestational age However, due to its low correlation, it is not a suitable screening test for clinical practice.

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