Short-Term Estradiol Replacement in Postmenopausal Women Selectively Mutes Somatostatin's Dose-Dependent Inhibition of Fasting Growth Hormone Secretion

2001 ◽  
Vol 86 (7) ◽  
pp. 3143-3149 ◽  
Author(s):  
M. J. Bray
Keyword(s):  
Growth Hormone ◽  
Postmenopausal Women ◽  
Hormone Secretion ◽  
Growth Hormone Secretion ◽  
Short Term ◽  
Dependent Inhibition ◽  
Dose Dependent Inhibition ◽  
Dose Dependent

Targeted, Dose-Dependent Inhibition of Growth Hormone Secretion by the Botulinum Neurotoxin-Based TSI SXN101000 and SXN101742

2011 ◽  
pp. P2-332-P2-332
Author(s):  
James Daniel Leggett ◽  
Eleanor Jane Waite ◽  
Philip Michael Hunt Marks ◽  
Alberto Martinez ◽  
Stafford Louis Lightman
Keyword(s):  
Growth Hormone ◽  
Botulinum Neurotoxin ◽  
Hormone Secretion ◽  
Growth Hormone Secretion ◽  
Inhibition Of Growth ◽  
Dependent Inhibition ◽  
Dose Dependent Inhibition ◽  
Dose Dependent

Short term pirenzepine treatment is ineffective in suppressing 24-h growth hormone secretion in type 1 diabetes mellitus

1993 ◽  
Vol 19 (3) ◽  
pp. 211-216 ◽  
Author(s):  
J. Krassowski ◽  
P. Szulc ◽  
A. Makowska ◽  
M. Godziejewska ◽  
W. Jeske ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Growth Hormone ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Hormone Secretion ◽  
Growth Hormone Secretion ◽  
Short Term

Growth hormone secretion in the guinea-pig

1990 ◽  
Vol 124 (3) ◽  
pp. 371-380 ◽  
Author(s):  
B. Gabrielsson ◽  
K. M. Fairhall ◽  
I. C. A. F. Robinson
Keyword(s):  
Growth Hormone ◽  
Guinea Pig ◽  
Guinea Pigs ◽  
Hormone Secretion ◽  
Growth Hormone Secretion ◽  
Physiological Control ◽  
Gh Secretion ◽  
Dose Dependent Fashion ◽  
Growth Promoting ◽  
Dose Dependent

ABSTRACT The guinea-pig is unusual in that it continues to grow at a normal rate after hypophysectomy. Although its pituitary gland appears to contain a GH, this has not been isolated or characterized, and nothing is known about its secretion or physiological control. We have identified guinea-pig GH, established a sensitive heterologous radioimmunoassay and adapted our automatic blood microsampling method to study spontaneous GH secretion in this species. In male guinea-pigs, GH is released in an episodic pattern, reminiscent of the rat. Large multicomponent pulses of GH secretion occur every 3–4 h between periods of low or undetectable GH release, whereas most females showed a more uniform pulsatile pattern with pulses every 1–2 h. GH was released in response to GH-releasing factor (GRF) injections (2, 10 or 20 μg [Nle27]-GRF(1–29)NH2) in a dose-dependent fashion, and i.v. infusion of somatostatin (50 μg/h) blocked spontaneous GH pulses, eliciting a rebound release (from 2·0±0·8 (s.e.m.) to 36±17 μg/l 30 min after stopping the infusion). Infusions of a GH-releasing hexapeptide (100 or 400 μg/h for 4 h) also released GH. These results provide the first description of the pattern of GH release in the guinea-pig, and suggest that the striking episodic pattern is controlled by the same hypothalamic peptides that regulate GH in other species. Since the guinea-pig grows well in the absence of GH, this species may use GH for its metabolic, rather than growth-promoting actions. The guinea-pig may well prove a useful model, now that methods are available for studying its endogenous GH secretion. Journal of Endocrinology (1990) 124, 371–380

scholarly journals Short-Term Treatment with Bromocriptine Improves Impaired Circadian Growth Hormone Secretion in Obese Premenopausal Women

2008 ◽  
Vol 93 (9) ◽  
pp. 3455-3461 ◽  
Author(s):  
Petra Kok ◽  
Ferdinand Roelfsema ◽  
Marijke Frölich ◽  
Johannes van Pelt ◽  
A. Edo Meinders ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Hormone Secretion ◽  
Growth Hormone Secretion ◽  
Premenopausal Women ◽  
Term Treatment ◽  
Short Term ◽  
Short Term Treatment
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