Relationship Between the Long-Acting Thyroid Stimulator and Circulating Thyroid Antibodies in Graves' Disease

1967 ◽  
Vol 27 (12) ◽  
pp. 1758-1760 ◽  
Author(s):  
A. PINCHERA ◽  
P. LIBERTI ◽  
R. DE SANTIS ◽  
L. GRASSO ◽  
E. MARTINO ◽  
...  
1973 ◽  
Vol 73 (3) ◽  
pp. 483-488 ◽  
Author(s):  
F. Adlkofer ◽  
H. Schleusener ◽  
L. Uher ◽  
A. Ananos ◽  
C. Brammeier

ABSTRACT Crude IgG of sera from 3 patients with Graves' disease, which contained LATS-activity and/or thyroid antibodies, was fractionated by isoelectric focusing in a pH-range between 6.0 to 10.0. LATS-activity was found in IgG-subfractions from pH 7.5 to 9.5, thyroglobulin antibodies and thyroid microsomal antibodies from pH 6.0 to 10.0. It was not possible to separate LATS-activity from the thyroid antibodies by this technique. The results indicate that LATS and the thyroid antibodies are heterogeneous and of polyclonal origin.


1970 ◽  
Vol 46 (3) ◽  
pp. 291-296 ◽  
Author(s):  
J. FÖLDES ◽  
J. TAKÓ ◽  
C. BÁNOS ◽  
E. GESZTESI ◽  
I. VARGA

SUMMARY In most cases of Graves' disease the level of iodotyrosines in the plasma is above normal. With a view to ascertaining the cause of this phenomenon simultaneous determinations were made of the iodotyrosine and long-acting thyroid stimulator (LATS) levels in the plasma and of the titre of thyroid antibodies. It was found that high plasma concentrations of iodotyrosines in exophthalmic goitre were mainly due to auto-immune thyroiditis, but that LATS may also contribute to the phenomenon.


2010 ◽  
Vol 35 (4) ◽  
pp. 183-187 ◽  
Author(s):  
Hiroyuki Kinoshita ◽  
Mutsuko Yasuda ◽  
Shingo Kaneko ◽  
Ryo Usui ◽  
Seiji Inoshita ◽  
...  

1967 ◽  
Vol 43 (4) ◽  
pp. 486-498 ◽  
Author(s):  
Leonard M. Lipman ◽  
Donald E. Green ◽  
Norton J. Snyder ◽  
Jerald C. Nelson ◽  
David H. Solomon

The Lancet ◽  
1970 ◽  
Vol 296 (7668) ◽  
pp. 335-338 ◽  
Author(s):  
E.A. Sellers ◽  
A.G. Awad ◽  
E. Schönbaum
Keyword(s):  

2017 ◽  
Vol 2017 ◽  
pp. 1-4
Author(s):  
Lilibet Urias-Uribe ◽  
Emmanuel Valdez-Solis ◽  
Claudia González-Milán ◽  
Claudia Ramírez-Rentería ◽  
Aldo Ferreira-Hermosillo

We present the case of a patient with previous psychiatric illness, acutely exacerbated by thyroid storm due to Graves’ disease, in whom treatment with antipsychotics induced catatonia. These associations are extremely rare and may be confused with Hashimoto’s encephalopathy, especially in the presence of anti-thyroid antibodies in cerebrospinal fluid. The treatment consists in the control of the triggering disease (in this case the resolution of the thyrotoxicosis) and the use of benzodiazepines. However, in some cases, the resolution of psychiatric symptoms is partial and may require the use of electroconvulsive therapy.


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