Suppression of the Positive Feedback of Estradiol Benzoate on Gonadotropin Secretion by an Inhibitory Analog of Luteinizing Hormone-Releasing Hormone (LRH) in Oophorectomized Rhesus Monkeys: Evidence for a Necessary Synergism between LRH and Estrogens*

1983 ◽  
Vol 57 (2) ◽  
pp. 367-372 ◽  
Author(s):  
R. H. ASCH ◽  
J. P. BALMACEDA ◽  
M. R. BORGHI ◽  
R. NIESVISKY ◽  
D. H. COY ◽  
...  
Endocrinology ◽  
1977 ◽  
Vol 101 (2) ◽  
pp. 430-434 ◽  
Author(s):  
J. D. NEILL ◽  
J. M. PATTON ◽  
R. A. DAILEY ◽  
R. C. TSOU ◽  
G. T. TINDALL

Endocrinology ◽  
1988 ◽  
Vol 122 (3) ◽  
pp. 884-890 ◽  
Author(s):  
JORG WINTERER ◽  
KEVIN M. BARNES ◽  
ALAN S. LICHTER ◽  
ANNE MARIE DELUCA ◽  
D. LYNN LORIAUX ◽  
...  

1977 ◽  
Vol 74 (3) ◽  
pp. 369-373 ◽  
Author(s):  
M. T. TSENG

SUMMARY Eighty micrograms of synthetic luteinizing hormone releasing hormone (LH-RH) were infused systemically into male and female foetuses of rhesus monkeys near term. Control animals were given infusions of saline. Morphologically, the control gonadotrophs varied from cells filled with secretory granules to highly stimulated cells with numerous cytoplasmic vesicles. In the LH-RH-treated animals, however, many cells showed depletion of secretory granules, dilatation of the endoplasmic reticulum and condensed nuclear chromatin. It is concluded, therefore, that foetal gonadotrophs can respond to administration of synthetic LH-RH.


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