In vitro stimulation of placental progesterone production by 19-nortestosterone and C19 steroids in early human pregnancy.

1992 ◽  
Vol 75 (3) ◽  
pp. 838-845
Author(s):  
J Begum-Hasan ◽  
B E Murphy
Keyword(s):  
Human Pregnancy ◽  
Progesterone Production ◽  
Early Human ◽  
Stimulation Of

Estrogen formation in vitro by fetal liver, fetal adrenal gland, and placenta of early human pregnancy

1970 ◽  
Vol 107 (2) ◽  
pp. 313-317 ◽  
Author(s):  
Chung-Hsiu Wu ◽  
George L. Flickinger ◽  
David F. Archer ◽  
Joseph C. Touchstone
Keyword(s):  
Adrenal Gland ◽  
Fetal Liver ◽  
Human Pregnancy ◽  
Early Human

Tokishakuyakusan Stimulates Progesterone and Estradiol-17 β Production by Rat Granulosa Cells and Progesterone, Testosterone and Estradiol-17 β by the Residual Portion of the Follicle in Vitro

1991 ◽  
Vol 19 (02) ◽  
pp. 155-161 ◽  
Author(s):  
Satoshi Usuki
Keyword(s):  
Granulosa Cells ◽  
Cell Level ◽  
Testosterone Production ◽  
Progesterone Production ◽  
Preovulatory Follicles ◽  
Immature Rats ◽  
Serum Gonadotropin ◽  
Tissue Compartments ◽  
Stimulation Of

To examine the possible effects of Tokishakuyakusan (TS) on steroidogenesis by preovulatory follicles at the cell level, the expressed granulosa cells and remaining portion of follicles from pregnant mare's serum gonadotropin (PMS)-treated immature rats were incubated in vitro with increasing concentrations of TS for 3 h. TS significantly stimulated progesterone and estradiol-17 b production, with a predominant stimulation of progesterone, by the expressed granulosa cells, while testosterone production was not stimulated. In the remaining portion of the follicle, TS also significantly stimulated progesterone, testosterone and estradiol-17 b production. Similar to the effect produced by granulosa cells, the stimulatory effect of TS was stronger on progesterone than on testosterone and estradiol-17 b production. These results suggest that TS has a potent, direct stimulatory effect on steroidogenesis, especially progesterone production, by constituent tissue compartments of rat preovulatory follicles in vitro.

Early human pregnancy in vitro utilizing an artificially perfused uterus

1988 ◽  
Vol 49 (6) ◽  
pp. 991-996 ◽  
Author(s):  
Carlo Bulletti ◽  
Valerio Maria Jasonni ◽  
Stefania Tabanelli ◽  
Luca Gianaroli ◽  
Patrizia Maria Ciotti ◽  
...  
Keyword(s):  
Human Pregnancy ◽  
Early Human

CONVERSION OF DEHYDROEPIANDROSTERONE-7α-3H TO OESTROGENS BY CORPUS LUTEUM, PLACENTA, AND PLACENTA PLUS FOETAL VISCERA IN EARLY HUMAN PREGNANCY

1967 ◽  
Vol 54 (1) ◽  
pp. 181-188 ◽  
Author(s):  
Chung-Hsiu Wu ◽  
George L. Flickinger ◽  
Joseph C. Touchstone
Keyword(s):  
Corpus Luteum ◽  
Early Pregnancy ◽  
Human Pregnancy ◽  
Early Human

ABSTRACT A corpus luteum, placenta, and placenta plus foetal viscera of a 13-week old human pregnancy were incubated with dehydroepiandrosterone-7α-3H in vitro. Conversion to oestrone and 17β-oestradiol was found in all incubates. Oestriol was formed from dehydroepiandrosterone only in the incubate of placenta plus foetal viscera. Thus, in early pregnancy dehydroepiandrosterone may serve as a precursor for oestrogen biosynthesis not only in the foeto-placental compartment, but also in the corpus luteum.

Catecholamine stimulation of cyclic AMP and progesterone production in rat corpora lutea of different ages

1982 ◽  
Vol 100 (4) ◽  
pp. 613-622 ◽  
Author(s):  
Ensio Norjavaara ◽  
Gunnar Selstam ◽  
Kurt Ahrén
Keyword(s):  
Cyclic Amp ◽  
Corpora Lutea ◽  
Progesterone Production ◽  
Different Ages ◽  
Adrenergic Antagonists ◽  
Β Blocker ◽  
In Vitro Effects ◽  
Higher Doses ◽  
Stimulation Of

Abstract. In vitro effects of catecholamines (adrenaline and noradrenaline) and adrenergic antagonists on adenosine 3′,5′-cyclic monophosphate (cAMP) and progesterone production by rat corpora lutea (CL) of different ages (1–8 days old) were studied. To obtain defined ages of CL a pregnant mare's serum gonadotrophin (PMSG) model was used. The effect of catecholamines on cAMP decreased with luteal age while the effect on progesterone production was maximal on 5 day old CL. The β-blocker propranolol inhibited the effects of catecholamines in concentrations around 10−5 m. The effects of LH could only be inhibited with higher doses of propranolol known to exert unspecific effects. These results support the theory that LH and catecholamine effects on rat corpora lutea are mediated through different receptors.

scholarly journals Serotonin-induced stimulation of progesterone production by cow luteal cells in vitro

Reproduction ◽  
1986 ◽  
Vol 76 (1) ◽  
pp. 231-238 ◽  
Author(s):  
P. J. Battista ◽  
W. A. Condon
Keyword(s):  
Luteal Cells ◽  
Progesterone Production ◽  
Stimulation Of
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