Vav3 Enhances Androgen Receptor Splice Variant Activity and Is Critical for Castration-Resistant Prostate Cancer Growth and Survival

Growth And Survival ◽

Castration Resistant ◽

Abstract 1069: Vav3 enhances androgen receptor splice variant activity and is critical for castration resistant prostate cancer growth and survival.

10.1158/1538-7445.am2013-1069 ◽

2013 ◽

Author(s):

Stephanie Peacock ◽

Cale D. Fahrenholtz ◽

Kerry L. Burnstein

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Splice Variant ◽

Cancer Growth ◽

Growth And Survival ◽

Castration Resistant ◽

The association between androgen receptor splice variant 7 status and prognosis of metastatic castration‐resistant prostate cancer: A systematic review and meta‑analysis

Andrologia ◽

10.1111/and.13642 ◽

2020 ◽

Vol 52 (7) ◽

Author(s):

Jiatong Zhou ◽

Ranlu Liu

Keyword(s):

Prostate Cancer ◽

Systematic Review ◽

Androgen Receptor ◽

Splice Variant ◽

Meta Analysis ◽

Castration Resistant ◽

Clinical Utility of Circulating Tumour Cell Androgen Receptor Splice Variant-7 Status in Metastatic Castration-resistant Prostate Cancer

European Urology ◽

10.1016/j.eururo.2019.04.006 ◽

2019 ◽

Vol 76 (5) ◽

pp. 676-685 ◽

Cited By ~ 22

Author(s):

Adam Sharp ◽

Jon C. Welti ◽

Maryou B.K. Lambros ◽

David Dolling ◽

Daniel Nava Rodrigues ◽

...

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Tumour Cell ◽

Splice Variant ◽

Clinical Utility ◽

Castration Resistant ◽

Circulating Tumour Cell ◽

Abstract 2148: Exploitation of androgen receptor splice variant signaling by guanine nucleotide exchange factor Vav3 in castration resistant prostate cancer

10.1158/1538-7445.am2012-2148 ◽

2012 ◽

Author(s):

Stephanie Peacock ◽

Cale Fahrenholtz ◽

Kerry L. Burnstein

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Splice Variant ◽

Guanine Nucleotide ◽

Nucleotide Exchange ◽

Guanine Nucleotide Exchange ◽

Castration Resistant ◽

Nucleotide Exchange Factor ◽

Abstract 2910: Androgen receptor splice variant-7 predicts resistance to enzalutamide in patients with castration-resistant prostate cancer

10.1158/1538-7445.am2014-2910 ◽

2014 ◽

Author(s):

Emmanuel S. Antonarakis ◽

Changxue Lu ◽

Hao Wang ◽

Brandon Luber ◽

Mary Nakazawa ◽

...

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Splice Variant ◽

Castration Resistant ◽

Use of nuclear-localized androgen receptor splice variant 7 protein in CTCs after 1st androgen receptor signaling inhibitor (ARSi) as a predictive biomarker for overall survival on a second ARSi or taxane chemotherapy in metastatic castration-resistant prostate cancer (mCRPC)

Annals of Oncology ◽

10.1093/annonc/mdy284.045 ◽

2018 ◽

Vol 29 ◽

pp. viii292-viii293

Author(s):

H.I. Scher ◽

R.P. Graf ◽

M. Hulling ◽

E. Carbone ◽

R. Dittamore

Keyword(s):

Prostate Cancer ◽

Overall Survival ◽

Androgen Receptor ◽

Splice Variant ◽

Predictive Biomarker ◽

Androgen Receptor Signaling ◽

Castration Resistant ◽

Androgen Receptor Splice Variant ◽

Taxane Chemotherapy

Reply to Julie Steinestel, Christof Bernemann, Andres J. Schrader, and Jochen K. Lennerz's Letter to the Editor re: Emmanuel S. Antonarakis, Changxue Lu, Brandon Luber, et al. Clinical Significance of Androgen Receptor Splice Variant-7 mRNA Detection in Circulating Tumor Cells of Men with Metastatic Castration-resistant Prostate Cancer Treated with First- and Second-line Abiraterone and Enzalutamide. J Clin Oncol 2017;35:2149–56. AR-V7 Testing: What's in it for the Patient?

European Urology ◽

10.1016/j.eururo.2017.06.032 ◽

2017 ◽

Vol 72 (6) ◽

pp. e170-e171 ◽

Author(s):

Jun Luo ◽

Brandon Luber ◽

Hao Wang ◽

Emmanuel S. Antonarakis

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Clin Oncol ◽

Tumor Cells ◽

Clinical Significance ◽

Splice Variant ◽

Second Line ◽

Castration Resistant ◽

Androgen receptor splice variant, AR-V7, and resistance to enzalutamide and abiraterone in men with metastatic castration-resistant prostate cancer (mCRPC).

Journal of Clinical Oncology ◽

10.1200/jco.2014.32.15_suppl.5001 ◽

2014 ◽

Vol 32 (15_suppl) ◽

pp. 5001-5001 ◽

Cited By ~ 10

Author(s):

Emmanuel S. Antonarakis ◽

Changxue Lu ◽

Hao Wang ◽

Brandon Luber ◽

Mary Nakazawa ◽

...

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Splice Variant ◽

Castration Resistant ◽

Current status of circulating tumor cell androgen receptor splice variant-7 in metastatic castration-resistant prostate cancer

Annals of Translational Medicine ◽

10.21037/atm.2019.12.137 ◽

2019 ◽

Vol 0 ◽

pp. S375-S375

Author(s):

Shinichi Sakamoto

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Tumor Cell ◽

Splice Variant ◽

Circulating Tumor Cell ◽

Current Status ◽

Castration Resistant ◽

Abstract 1335: Digital droplet PCR (ddPCR)-based detection of androgen receptor splice variant 7 (AR-v7) in non-metastatic castration resistant prostate cancer

10.1158/1538-7445.am2019-1335 ◽

2019 ◽

Author(s):

Mel Pilar Espaillat ◽

Yashoda Rajpurohit ◽

Mike Gormley ◽

Denis Smirnov ◽

Ian McCaffery ◽

...

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Splice Variant ◽

Digital Droplet Pcr ◽

Castration Resistant ◽

Droplet Pcr ◽