Abstract. Upper respiratory tract infections are the most common infections reported by elite athletes. Low vitamin D status has been associated with an increased risk of upper respiratory tract infections. The aim of this study was to investigate associations between serum 25-hydroxyvitamin D (25(OH)D), salivary immunoglobulin A (S-IgA) concentrations, and acute respiratory tract infections (colds/flu) (ARI) in elite rowers and rugby players. A total of 53 (23 rugby players, 30 rowers) elite New Zealand athletes volunteered to participate in an interview, and to provide a blood and a saliva sample. Testing occurred twice, 6 months apart. Athletes’ serum 25(OH)D concentrations and s-IgA levels were both significantly higher in summer, 108.9 (CI 102.8, 115.4) nmol/L, than in winter, 86.8 (CI 81.8, 92.1) nmol/L (p < 0.01, p = 0.028). The occurrence of an acute respiratory tract infection did not differ significantly between the time points (p = 0.322). However, ARI duration was significantly longer in winter than in summer (6.9 ± 4.3 days vs 4.8 ± 3.0 days; p = 0.044). There were no significant correlations between athletes’ 25(OH)D levels and their s-IgA levels (p > 0.05) nor with acute respiratory tract infection occurrence (p > 0.05) nor duration (p > 0.05) in summer or winter. These findings suggest there may not be any associations between serum 25(OH)D concentrations and acute respiratory tract infections in this population. However, this null finding may be attributed to the high vitamin D concentrations seen in these athletes.
Effect of High-Dose vs Standard-Dose Wintertime Vitamin D Supplementation on Viral Upper Respiratory Tract Infections in Young Healthy Children