Cerebral MR venography of transverse sinuses in subjects with normal CSF pressure

The association of idiopathic intracranial hypertension (IIH) with stenosis or narrowing of the transverse sinuses (TSs) is well known. However, there is debate as to whether the stenosis is a cause or consequence. Here we describe a case of IIH and narrowing of the TSs, with four relapses and recoveries after repeated CSF diversions with lumbar puncture (LP) over 2 months. Subsequently, implantation of a lumboperitoneal shunt (LPrS) ensured recovery. MR venography 20 months after LPrS showed normally calibrated TSs. We show repeated MR venography findings before and after the LPs, and discuss the pathogenesis of IIH in terms of the cause and effect relationship between IIH and sinus collapse.

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Abnormal pressure waves in headache sufferers with bilateral transverse sinus stenosis

Cephalalgia ◽

10.1177/0333102410370877 ◽

2010 ◽

Vol 30 (12) ◽

pp. 1419-1425 ◽

Cited By ~ 36

Author(s):

F Bono ◽

D Salvino ◽

T Tallarico ◽

D Cristiano ◽

F Condino ◽

...

Keyword(s):

Transverse Sinus ◽

Pressure Waves ◽

Pressure Monitoring ◽

Opening Pressure ◽

Short Term ◽

Normal Appearance ◽

Csf Pressure ◽

Abnormal Pressure ◽

Sinus Stenosis ◽

Transverse Sinuses

Introduction: Bilateral transverse sinus stenosis (BTSS) has been reported to be associated with idiopathic intracranial hypertension without papilloedema in headache sufferers. Subjects and methods: To test the accuracy of short-term cerebrospinal fluid (CSF) pressure monitoring through a lumbar needle for detection of elevated intracranial pressure in headache sufferers with BTSS, we prospectively performed lumbar puncture in order to measure lumbar CSF opening pressures and to monitor, for 1 h, the CSF pressure in 48 consecutive headache sufferers with BTSS and in 50 consecutive headache sufferers with normal appearance of transverse sinuses or stenosis of one transverse sinus. Results: Of the 48 headache sufferers with BTSS, 18 (37.5%) had elevated CSF opening pressure and abnormal pressure waveforms, but short-term CSF pressure monitoring revealed abnormal pressure waves associated with elevated mean CSF pressure also in 26 (86.6%) out of 30 patients who had normal opening pressures. None of the 50 headache sufferers with normal appearance of transverse sinuses or stenosis of one transverse sinus had abnormal pressure waves and elevated CSF pressures. Conclusions: In this study, short-term CSF pressure monitoring through a lumbar needle revealed abnormal pressure waves and elevated mean CSF pressures in the majority of headache sufferers with BTSS who had normal CSF opening pressures. These findings demonstrate the accuracy of short-term CSF pressure monitoring through a lumbar needle in estimating CSF pressure; they also highlight that a single-spot opening pressure measurement has a low accuracy for recognition of increased intracranial pressure in headache sufferers with BTSS.

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Obesity does not induce abnormal CSF pressure in subjects with normal cerebral MR venography

Neurology ◽

10.1212/01.wnl.0000035628.81384.5f ◽

2002 ◽

Vol 59 (10) ◽

pp. 1641-1643 ◽

Cited By ~ 36

Author(s):

F. Bono ◽

M. R. Lupo ◽

P. Serra ◽

C. Cantafio ◽

A. Lucisano ◽

...

Keyword(s):

Mr Venography ◽

Csf Pressure

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Hemodynamically significant venous collapse underlying neonatal hydrocephalus

Journal of Neurosurgery Pediatrics ◽

10.3171/2013.10.peds13343 ◽

2014 ◽

Vol 13 (2) ◽

pp. 125-132 ◽

Cited By ~ 6

Author(s):

Grant A. Bateman

Keyword(s):

Vascular Resistance ◽

Tertiary Care ◽

Maximum Size ◽

Vascular Compression ◽

Mr Venography ◽

Significant Elevation ◽

Capillary Bed ◽

Csf Diversion ◽

Transverse Sinuses ◽

Subependymal Veins

Object It is known that CSF diversion in neonatal hydrocephalus can significantly increase cerebral blood flow, suggesting that a rapidly reversible elevation in vascular resistance underlies this disorder. Various sites of vascular compression have been described in the literature, from the arterioles to the capillary bed to the venules and sinuses. The purpose of this study was to define the site of the hemodynamically significant vascular compression seen in neonatal hydrocephalus. Methods The author performed a retrospective review of all patients who, in the first 28 days of life, had undergone 3-T MRI examination, including MR venography and susceptibility weighted scanning, at a tertiary care referral hospital in the period from April 2010 to April 2013. The maximum size of the subependymal veins over the thalamus and transverse sinuses was measured. Results Three children with hydrocephalus were identified, and 10 children with a normal ventricular size served as controls. The subependymal veins were twice as prominent and the transverse sinuses were half as large in the patients with hydrocephalus compared with those in controls. Conclusions The hemodynamically significant elevation in vascular resistance, which occurs in neonatal hydrocephalus, appears to be located in the venous sinuses.

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The Usefulness of Three-Dimensional Gadolinium-Enhanced MR Venography for the Evaluation of Varices in Lower Extremities

Journal of the Korean Radiological Society ◽

10.3348/jkrs.2001.45.5.465 ◽

2001 ◽

Vol 45 (5) ◽

pp. 465

Author(s):

Myong Kwan Ko ◽

Hee Lee ◽

Sung Gwon Kang ◽

Jeong Yeol Choi ◽

Ju Nam Byun ◽

...

Keyword(s):

Three Dimensional ◽

Lower Extremities ◽

Mr Venography

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The sentinel node invasion level (SNIL) as a prognostic parameter in melanoma

Modern Pathology ◽

10.1038/s41379-021-00835-5 ◽

2021 ◽

Author(s):

Lutz Kretschmer ◽

Christina Mitteldorf ◽

Simin Hellriegel ◽

Andreas Leha ◽

Alexander Fichtner ◽

...

Keyword(s):

Lymph Node ◽

Prognostic Significance ◽

Tumor Burden ◽

Recurrence Rates ◽

Cox Models ◽

Nodal Basin ◽

Lymph Vessels ◽

Kaplan Meier ◽

Metastasis Patterns ◽

Transverse Sinuses

AbstractSentinel lymph node (SN) tumor burden is becoming increasingly important and is likely to be included in future N classifications in melanoma. Our aim was to investigate the prognostic significance of melanoma infiltration of various anatomically defined lymph node substructures. This retrospective cohort study included 1250 consecutive patients with SN biopsy. The pathology protocol required description of metastatic infiltration of each of the following lymph node substructures: intracapsular lymph vessels, subcapsular and transverse sinuses, cortex, paracortex, medulla, and capsule. Within the SN with the highest tumor burden, the SN invasion level (SNIL) was defined as follows: SNIL 1 = melanoma cells confined to intracapsular lymph vessels, subcapsular or transverse sinuses; SNIL 2 = melanoma infiltrating the cortex or paracortex; SNIL 3 = melanoma infiltrating the medulla or capsule. We classified 338 SN-positive patients according to the non-metric SNIL. Using Kaplan–Meier estimates and Cox models, recurrence-free survival (RFS), melanoma-specific survival (MSS) and nodal basin recurrence rates were analyzed. The median follow-up time was 75 months. The SNIL divided the SN-positive population into three groups with significantly different RFS, MSS, and nodal basin recurrence probabilities. The MSS of patients with SNIL 1 was virtually identical to that of SN-negative patients, whereas outgrowth of the metastasis from the parenchyma into the fibrous capsule or the medulla of the lymph node indicated a very poor prognosis. Thus, the SNIL may help to better assess the benefit-risk ratio of adjuvant therapies in patients with different SN metastasis patterns.

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Three-dimensional low dose gadolinium-enhanced peripheral MR venography

Journal of Magnetic Resonance Imaging ◽

10.1002/jmri.1880080317 ◽

1998 ◽

Vol 8 (3) ◽

pp. 630-633 ◽

Cited By ~ 38

Author(s):

Wei Li ◽

Vivek David ◽

Richard Kaplan ◽

Robert R. Edelman

Keyword(s):

Low Dose ◽

Three Dimensional ◽

Mr Venography

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Role of MR venography in the evaluation of deep venous thrombosis

Acta Radiologica ◽

10.1080/02841859709172434 ◽

1997 ◽

Vol 38 (5) ◽

pp. 907-912 ◽

Cited By ~ 25

Author(s):

C. Catalano ◽

P. Pavone ◽

A. Laghi ◽

A. Scipioni ◽

F. Fanelli ◽

...

Keyword(s):

Venous Thrombosis ◽

Deep Venous Thrombosis ◽

Sensitivity And Specificity ◽

Filling Defect ◽

Clinical Suspicion ◽

Mr Venography ◽

Diagnostic Modalities ◽

Positive Results ◽

Intraluminal Filling Defect

Purpose: MR venography has been recommended for the evaluation of deep venous thrombosis. The purpose of our study was to determine the role of MR venography, in particular at the level of the pelvis where other diagnostic modalities show major limitations. Materials and Methods: Forty-three patients with clinical suspicion of deep venous thrombosis were examined by means of pelvic MR venography. In all cases, a 2D-TOF sequence was used with cranial arterial presaturation. In selected cases, i.e. when a small intraluminal filling defect was present, a cine-PC sequence was used in addition in order to exclude the presence of a pulsatility artifact as causing the filling defect. In all cases, contrast venography was also performed and considered to be the standard of reference. Results: MR venography showed 26 patients to be positive for deep venous thrombosis at the pelvic level. These positive results were correct in 25 cases. The analysis of the results provided values of sensitivity and specificity of respectively 100% and 94%, with an overall accuracy of 97.6%. Conclusion: Our results indicate that MR can provide highly accurate images, similar to those of contrast venography, in a noninvasive fashion. It is particularly useful in the pelvic region where the limitations of other imaging modalities are more evident.

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