scholarly journals Clinical Reasoning: Transient speech deficits in a patient with history of medulloblastoma

Neurology ◽  
2018 ◽  
Vol 91 (22) ◽  
pp. 1031.1-1031
Neurology ◽  
2018 ◽  
Vol 91 (12) ◽  
pp. e1196-e1201
Author(s):  
Jessica D. Schulte ◽  
Gunnar Hargus ◽  
Peter Canoll ◽  
Michael B. Sisti ◽  
Tony J.C. Wang ◽  
...  

Neurology ◽  
2021 ◽  
pp. 10.1212/WNL.0000000000012486
Author(s):  
Anna Sofie Jakobsson ◽  
Ditte Gry Strange ◽  
Kirsten Møller ◽  
Daniel Kondziella

Neurology ◽  
2020 ◽  
Vol 95 (14) ◽  
pp. e2038-e2042
Author(s):  
Garland Tang ◽  
David R. Benavides

Neurology ◽  
2015 ◽  
Vol 85 (14) ◽  
pp. e104-e107
Author(s):  
Anoopum Gupta ◽  
Mark R. Etherton ◽  
Kathleen McKee ◽  
Jessica M. Baker ◽  
Saef Izzy ◽  
...  

Neurology ◽  
2017 ◽  
Vol 89 (19) ◽  
pp. e231-e234 ◽  
Author(s):  
Josef Maxwell Gutman ◽  
Michael Levy ◽  
Steven Galetta ◽  
Ilya Kister

Neurology ◽  
2011 ◽  
Vol 77 (24) ◽  
pp. e145-e148 ◽  
Author(s):  
M. H. Lee ◽  
J. M. Pritchard ◽  
W. J. Weiner

2019 ◽  
Vol 152 (Supplement_1) ◽  
pp. S69-S69
Author(s):  
Suhalika Sahni ◽  
Vikas Mehta

Abstract Objective The approach to a patient presenting with a rectal mass who has a history of bright red blood per rectum (BRBPR) renders a wide range of differential diagnoses. The clinical reasoning to suspect prostatic ductal adenocarcinoma (PDA) in a patient with BRBPR without a classical clinical presentation is highly unlikely. The incidence of PDA is rare with only 0.4% to 0.8% in pure ductal origin. Methods A 71-year-old African American male presented with 3-month history of watery, bloody diarrhea and a recent history of BRBPR with unintentional weight loss. Patient underwent colonoscopy, which showed a large polyp 10 cm from the anal verge, measuring 7 cm. The unclear history of this patient contributed to an initial impression of a colorectal cancer leading to a biopsy of the colonic mass. Results An erroneous diagnosis of tubulovillous adenoma was rendered initially. Further workup showed a large mass originating from the prostate area that was seen penetrating the colorectal region on an abdominal CT scan. The patient’s serum prostate-specific antigen (PSA) level was alarmingly high (4,800 ng/mL) and a subsequent prostate biopsy showed PDA. The colonic biopsy was reviewed again by a genitourinary pathologist and a correct diagnosis was rendered. Conclusion The role of pathology in diagnosing PDA is crucial as patients with PDA can have normal digital rectal examination (DRE) as well as a normal serum PSA level (less than 4.0 ng/mL). Majority of PDAs originate from periurethral prostatic ducts. The unique presentation of primary prostate pathology offers appreciation into the approach and workups to diagnose PDA. Diagnosing PDA can be challenging due to its more aggressive nature of PDA compared to prostatic acinar adenocarcinoma. The clinical reasoning and pathological findings from this rare case can aid clinicians and pathologists to establish the diagnosis of PDA in a timely and efficient manner.


Neurology ◽  
2020 ◽  
Vol 95 (22) ◽  
pp. e3065-e3069
Author(s):  
Valerie Jeanneret ◽  
Ryan B. Peterson ◽  
Carlos S. Kase

Electronics ◽  
2021 ◽  
Vol 10 (17) ◽  
pp. 2075
Author(s):  
Fabrizio Pecoraro ◽  
Fabrizio L. Ricci ◽  
Fabrizio Consorti ◽  
Daniela Luzi ◽  
Oscar Tamburis

Clinical reasoning in multimorbidity conditions asks for the ability to anticipate the possible evolutions of the overall health state of a patient and to identify the interactions among the concurrent health issues and their treatments. The HIN (Health Issue Network) approach, as Petri Nets-based formal language, is introduced as capable of providing a novel perspective to facilitate the acquisition of such competencies, graphically representing the network among a set of health issues (HIs) that affect a person throughout their life, and describing how HIs evolve over time. The need to provide a more immediate user-oriented interface has led to the development of f-HIN (friendly HIN), a lighter version based on the same mathematical properties as HIN, from which stems in turn the f-HINe (friendly HIN extracted) model, used to represent networks related to either real patients’ clinical experiences extracted from electronic health records, or from teacher-designed realistic clinical histories. Such models have also been designed to be embedded in a software learning environment that allows drawing a f-HIN diagram, checking for its format correctness, as well as designing clinical exercises for the learners, including their computer-assisted assessment. The present paper aims at introducing and discussing the f-HIN/f-HINe models and their educational use. It also introduces the main features of the software learning environment it was built upon, pointing out its importance to: (i) help medical teachers in designing and representing the context of a learning outcome; and (ii) handle the complex history of a multimorbidity patient, to be conveyed in Case-Based Learning (CBL) exercises.


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