scholarly journals Adherence with psychotherapy and treatment outcomes for psychogenic nonepileptic seizures

Neurology ◽  
2019 ◽  
Vol 92 (7) ◽  
pp. e675-e679 ◽  
Author(s):  
Benjamin Tolchin ◽  
Barbara A. Dworetzky ◽  
Steve Martino ◽  
Hal Blumenfeld ◽  
Lawrence J. Hirsch ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Childhood Abuse ◽  
Odds Ratio ◽  
Care Center ◽  
Medium Effect ◽  
Psychogenic Nonepileptic Seizures ◽  
History Of ◽  
Nonepileptic Seizures

ObjectiveWe conducted a prospective cohort study of patients with psychogenic nonepileptic seizures (PNES) to examine the association between adherence with psychotherapy and outcomes, including significant (≥50%) reduction in PNES frequency, PNES freedom, improvement in quality of life, and reduction in emergency department (ED) utilization.MethodsA total of 105 participants were referred to receive psychotherapy either at Brigham and Women's Hospital or with a local therapist. We called participants at 12–24 months follow-up and obtained detailed follow-up data from 93 participants (89%). Participants were considered adherent with psychotherapy if they attended at least 8 sessions within a 16-week period starting at the time of referral.ResultsAdherence with psychotherapy was associated with reduction in seizure frequency (84% in adherent group vs 61% in nonadherent, p = 0.021), improvement in quality of life (p = 0.044), and reduction in ED utilization (p = 0.040), with medium effect sizes; there was no difference in PNES freedom. The association between adherence and ≥50% reduction in PNES frequency persisted when controlling for potential confounders in a multivariate model. Psychotherapy nonadherence was associated with baseline characteristics of self-identified minority status (odds ratio 7.47, p = 0.019) and history of childhood abuse (odds ratio 3.30, p = 0.023).ConclusionsOur study is limited in that it cannot establish a causal relationship between adherence with psychotherapy and outcomes, and the results may not generalize beyond the single quaternary care center study site. Among participants with documented PNES, adherence with psychotherapy was associated with reduction in PNES frequency, improvement in quality of life, and decrease in ED visits.

Quality of Life in Psychogenic Nonepileptic Seizures

Epilepsia ◽  
2003 ◽  
Vol 44 (2) ◽  
pp. 236-242 ◽  
Author(s):  
Jerzy P. Szaflarski ◽  
Cynthia Hughes ◽  
Magdalena Szaflarski ◽  
David M. Ficker ◽  
William T. Cahill ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Psychogenic Nonepileptic Seizures ◽  
Nonepileptic Seizures

Natural history of Charcot–Marie-Tooth 2: 2-year follow-up of muscle strength, walking ability and quality of life

2009 ◽  
Vol 31 (2) ◽  
pp. 175-178 ◽  
Author(s):  
Luca Padua ◽  
D. Pareyson ◽  
I. Aprile ◽  
T. Cavallaro ◽  
D. A. Quattrone ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Muscle Strength ◽  
Natural History ◽  
Walking Ability ◽  
Charcot Marie Tooth ◽  
History Of

Outcomes in the treatment of psychogenic nonepileptic seizures (PNES) with CBTip: Response in seizure frequency, depression, anxiety, and quality of life

2021 ◽  
Vol 123 ◽  
pp. 108277
Author(s):  
Becky Bikat S. Tilahun ◽  
Nicolas R. Thompson ◽  
Lauren R. Sankary ◽  
Firdaws Laryea ◽  
Charles M. Trunick ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Seizure Frequency ◽  
Psychogenic Nonepileptic Seizures ◽  
Nonepileptic Seizures

Quality of life in psychogenic nonepileptic seizures and epilepsy: The role of somatization and alexithymia

2015 ◽  
Vol 43 ◽  
pp. 81-88 ◽  
Author(s):  
Laurie Dempsey Wolf ◽  
Joseph G. Hentz ◽  
Kristine S. Ziemba ◽  
Kristin A. Kirlin ◽  
Katherine H. Noe ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Psychogenic Nonepileptic Seizures ◽  
Nonepileptic Seizures

scholarly journals Impact of family functioning on quality of life in patients with psychogenic nonepileptic seizures versus epilepsy

Epilepsia ◽  
2011 ◽  
pp. no-no ◽  
Author(s):  
W. Curt LaFrance Jr. ◽  
Michael L. Alosco ◽  
Jennifer Duncan Davis ◽  
Geoffrey Tremont ◽  
Christine E. Ryan ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Family Functioning ◽  
Psychogenic Nonepileptic Seizures ◽  
Nonepileptic Seizures

scholarly journals Natural history of reflux oesophagitis: a 10 year follow up of its effect on patient symptomatology and quality of life.

Gut ◽  
1996 ◽  
Vol 38 (4) ◽  
pp. 481-486 ◽  
Author(s):  
N I McDougall ◽  
B T Johnston ◽  
F Kee ◽  
J S Collins ◽  
R J McFarland ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Natural History ◽  
Reflux Oesophagitis ◽  
History Of ◽  
Reflux Œsophagitis

scholarly journals Tucked and treated- a case series on outcome of meshplasty with abdominoplasty for incisional hernia

2021 ◽  
Vol 8 (11) ◽  
pp. 3421
Author(s):  
Nagamallesh C. S. ◽  
Nandini S. Tanwar ◽  
F. Sadiq Nawaz ◽  
Padmanath Bhat
Keyword(s):  
Quality Of Life ◽  
Incisional Hernia ◽  
Previous History ◽  
Case Series ◽  
Weight Lifting ◽  
Aesthetic Outcome ◽  
Strict Glycemic Control ◽  
History Of

Incisional hernia is the second most common type of hernia. Incisional hernia occurs in 10-20% of patients who were subjected to abdominal surgery in India. Here we are presenting a case series of 20 patients with incisional hernia and obesity. Body mass index (BMI) ranges from 28 to 35 in all cases. Females outnumbered the male in the ratio of 4:1 and 40% of cases had a previous history of caesarean section. All cases were operated by combining open polypropylene meshplasty and abdominoplasty techniques and follow up consultations were done for 1 year. 10% of cases had post-op wound infections, who were known to be diabetic. They were managed with appropriate antibiotics and maintained strict glycemic control. 90% of patients were satisfied from the procedure performed which improved their quality of life, significant cosmetic outcome and no recurrence. 10% of cases had recurrence after heavy weight lifting following surgery (BMI was 36). By incorporating the above mentioned techniques in hernia repair, recurrence rate and complications were reduced, quality of life and aesthetic outcome are enhanced.

Allogeneic Transplantation from an HLA-Matched Family Donor in First Complete Remission of Acute Myeloid Leukemia Had an Adverse Impact on Quality of Life in Patients Followed for at Least Five Years after Treatment: A Survey of the German AML Intergroup on 525 Patients.

Blood ◽  
2005 ◽  
Vol 106 (11) ◽  
pp. 747-747
Author(s):  
Dorle Messerer ◽  
Jutta Engel ◽  
Jörg Hasford ◽  
Markus Schaich ◽  
Silke Soucek ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Health Status ◽  
Global Health ◽  
Odds Ratio ◽  
Cardiac Insufficiency ◽  
Global Health Status ◽  
Concomitant Disease ◽  
The Impact

Abstract The impact of allogeneic blood stem cell transplantation (Allo-SCT) in comparison to conventional chemotherapy (CCT) in AML on quality of life remains unclear mainly due to a lack of studies with long term follow-up. Therefore the German AML-Intergroup initiated a survey on quality of life for patients treated within 1 of 8 German prospective multicenter treatment trials. All patients completed a self-report questionnaire either when they returned for follow-up outpatient visits or by mail. Patients completed the EORTC Quality of Life-Core Questionnaire (QLQ-C30) supplemented by self-assessed concomitant diseases, late treatment effects and demographic details including percentage of disability. 525 patients (median age: 46 years at diagnosis; median follow up period: 9 years) returned their questionnaires, 244 after SCT in 1. CR (189 allo; 55 auto) and 281 after CCT. Recovery-rate of the questionnaires was 55% ranging from 40% to 79% in the different trial cohorts. Due to low numbers after auto-SCT these patients were excluded from further analysis. The ECOG activity index revealed normal activity in 40% and 58% and disabled person card in 63% and 37% of the patients in the allo-SCT and CCT groups, respectively. Impaired vision, cataract surgery, chronic skin disorders and treatment of hormonal disorders were reported significantly more often in allo-SCT-patients, whereas osteoarthritis, cardiac insufficiency and unspecific back pain were slightly more frequent in CCT patients, mainly due to a higher median age in the CCT-group. All QLQC-30 functions except physical functioning and pain were in favor of CCT (p<0.001 in each variable). Problems in leisure-time activity, evenness and social life (friends and family) as well as financial management were significantly more frequent in patients after Allo-SCT than in patients after CCT, whereas the general assessment of positive attitude in life showed no difference between the two groups (62% CCT and 64% Allo-SCT). Multivariate logistic regression models on global health status and fatigue were performed. Actually concomitant disease (odds ratio 6.68 95%-CI 3.83–11.66), age > 45 years (odds-ratio 2.57 95%-CI 1.47–4.50) and Allo-SCT (odds ratio 2.10 95%-CI 1.20 – 3.69) showed significant adverse effect on global health status. Similarly unfavorable effects were evaluated for actually concomitant disease and Allo-SCT on fatigue. These results indicate that Allo-SCT compared to intensive chemotherapy had a significant negative impact on quality of life and this needs to be considered when reviewing treatment options.

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