Induction of visual extinction by rapid-rate transcranial magnetic stimulation of parietal lobe

Neurology ◽  
1994 ◽  
Vol 44 (3, Part 1) ◽  
pp. 494-494 ◽  
Author(s):  
A. Pascual-Leone ◽  
E. Gomez-Tortosa ◽  
J. Grafman ◽  
D. Alway ◽  
P. Nichelli ◽  
...  
Keyword(s):  
Transcranial Magnetic Stimulation ◽  
Magnetic Stimulation ◽  
Parietal Lobe ◽  
Rapid Rate ◽  
Visual Extinction ◽  
Stimulation Of

scholarly journals The Role of the Parietal Lobe in Visual Extinction Studied with Transcranial Magnetic Stimulation

2009 ◽  
Vol 21 (10) ◽  
pp. 1946-1955 ◽  
Author(s):  
Lorella Battelli ◽  
George A. Alvarez ◽  
Thomas Carlson ◽  
Alvaro Pascual-Leone
Keyword(s):  
Transcranial Magnetic Stimulation ◽  
Visual Tracking ◽  
Magnetic Stimulation ◽  
Posterior Parietal Cortex ◽  
Parietal Lobe ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Visual Fields ◽  
Brain Regions ◽  
Visual Extinction ◽  
Interhemispheric Competition

Interhemispheric competition between homologous areas in the human brain is believed to be involved in a wide variety of human behaviors from motor activity to visual perception and particularly attention. For example, patients with lesions in the posterior parietal cortex are unable to selectively track objects in the contralesional side of visual space when targets are simultaneously present in the ipsilesional visual field, a form of visual extinction. Visual extinction may arise due to an imbalance in the normal interhemispheric competition. To directly assess the issue of reciprocal inhibition, we used fMRI to localize those brain regions active during attention-based visual tracking and then applied low-frequency repetitive transcranial magnetic stimulation over identified areas in the left and right intraparietal sulcus to asses the behavioral effects on visual tracking. We induced a severe impairment in visual tracking that was selective for conditions of simultaneous tracking in both visual fields. Our data show that the parietal lobe is essential for visual tracking and that the two hemispheres compete for attentional resources during tracking. Our results provide a neuronal basis for visual extinction in patients with parietal lobe damage.

Transcranial Magnetic Stimulation of Human Parietal Lobe Relieves Induced Pain through Endorphin Release

1999 ◽  
pp. 975-977
Author(s):  
Vahe E. Amassian ◽  
Manuel S. Vergara ◽  
Mahendra Somasundaram ◽  
Paul J. Maccabee ◽  
Roger Q. Cracco
Keyword(s):  
Transcranial Magnetic Stimulation ◽  
Magnetic Stimulation ◽  
Parietal Lobe ◽  
Stimulation Of

Responses to rapid-rate transcranial magnetic stimulation of the human motor cortex

Brain ◽  
1994 ◽  
Vol 117 (4) ◽  
pp. 847-858 ◽  
Author(s):  
Alvaro Pascual-Leone ◽  
Josep Valls-Solé ◽  
Eric M. Wassermann ◽  
Mark Hallett
Keyword(s):  
Transcranial Magnetic Stimulation ◽  
Motor Cortex ◽  
Magnetic Stimulation ◽  
Rapid Rate ◽  
Human Motor Cortex ◽  
Human Motor ◽  
Stimulation Of

Dose-Dependent Reduction of Cerebral Blood Flow During Rapid-Rate Transcranial Magnetic Stimulation of the Human Sensorimotor Cortex

1998 ◽  
Vol 79 (2) ◽  
pp. 1102-1107 ◽  
Author(s):  
Tomáš Paus ◽  
Robert Jech ◽  
Christopher J. Thompson ◽  
Roch Comeau ◽  
Terry Peters ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Transcranial Magnetic Stimulation ◽  
Sensorimotor Cortex ◽  
Magnetic Stimulation ◽  
Frameless Stereotaxy ◽  
Rapid Rate ◽  
Primary Sensorimotor Cortex ◽  
Dose Dependent ◽  
Stimulation Of

Paus, Tomáš, Robert Jech, Christopher J. Thompson, Roch Comeau, Terry Peters, and Alan C. Evans. Dose-dependent reduction of cerebral blood flow during rapid-rate transcranial magnetic stimulation of the human sensorimotor cortex. J. Neurophysiol. 79: 1102–1107, 1998. Rapid-rate transcranial magnetic stimulation (rTMS) was used to stimulate the primary sensorimotor cortex in six healthy volunteers while regional changes in cerebral blood flow (CBF) were simultaneously measured by means of positron emission tomography. A figure-eight TMS coil (Cadwell Corticoil) was positioned, using frameless stereotaxy, over the probabilistic location of the left primary sensorimotor cortex, and a series of brief 10-Hz trains of TMS was delivered at subthreshold intensity during each of six 60-s scans. The scans differed in the number of trains delivered, namely 5, 10, 15, 20, 25, and 30 trains/scan, respectively. In the left primary sensorimotor cortex, CBF covaried significantly and negatively with the number of stimulus trains. These CBF decreases may reflect TMS–induced activation of local inhibitory mechanisms known to play a role in TMS–related phenomena, such as the electromyographic silent period.

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