The Effect of Nitroglycerin on Pacing-Induced Changes in Myocardial Oxygen Consumption and Metabolic Coronary Vasodilation in Patients with Coronary Artery Disease

1999 ◽  
Vol 88 (2) ◽  
pp. 271-278
Author(s):  
Jasper E. Kal ◽  
Isabelle Vergroesen ◽  
Harry B. van Wezel
2005 ◽  
Vol 13 (1) ◽  
pp. 34-37 ◽  
Author(s):  
Arash Arya ◽  
Majid Maleki ◽  
Fereydoon Noohi ◽  
Ebrahim Kassaian ◽  
Farideh Roshanali

One hundred and thirty-six men with coronary artery disease were randomly assigned to a hospital-based or home-based exercise program of 3 sessions per week. A treadmill test was carried out with the modified Naughton protocol. After 3 months, 125 patients (92%) with a mean age of 55 ± 11 years had completed the study. Maximum workload achieved increased by 65% [(12.40 ± 1.32 vs. 7.50 ± 0.85 metabolic equivalent units (METs)] in the hospital-based group, and by 17% (8.86 ± 0.9 vs. 7.56 ± 0.78 METs) in the home-based group ( p = 0.0001). The heart rate-blood pressure product, an index of myocardial oxygen consumption, decreased at rest by 19% in the hospital-based group but was unchanged in the home-based group ( p = 0.0001). The heart rate-blood pressure product at 5 and 7 METs activity level decreased 28% and 26%, respectively, in the hospital-based group vs. 8% and 2% in the home-based group ( p = 0.0001). It was concluded that hospital-based exercise training in patients with coronary artery disease improves functional capacity and decreases the myocardial oxygen consumption index at rest and during exercise.


2020 ◽  
Vol 9 (6) ◽  
pp. 1889
Author(s):  
Won Young Jang ◽  
Dong Oh Kang ◽  
Yoonjee Park ◽  
Jieun Lee ◽  
Woohyeun Kim ◽  
...  

The regression equation of the American College of Sports Medicine (ACSM) was a preferred method for estimating maximal oxygen consumption (VO2max). Recently, a more precise equation from the fitness registry and the importance of exercise national database (FRIEND) for healthy people was developed. This study compared VO2max estimated by the ACSM and FRIEND equations to VO2max directly measured in coronary artery disease (CAD) patients. Overall, 293 CAD patients who participated in cardiac rehabilitation between June 2015 and December 2018 were analyzed. Directly measured VO2max values were compared to the ACSM and FRIEND equations. The directly measured VO2max was significantly different from the estimated VO2max by ACSM equation (24.16 vs. 28.7 mL/kg/min, p < 0.001), which was overestimated by 20% in men and 16% in women. However, there was no statistically significant difference between the directly measured VO2max and the estimated VO2max by the FRIEND equation. (24.16 vs. 24.15 mL/kg/min, p = 0.986). In CAD patients, the estimated VO2max from the ACSM equation was significantly higher than the directly measured VO2max. In addition, estimated cardiorespiratory fitness (CRF) by the FRIEND equation showed similar results with directly measured CRF. As a result, the FRIEND equation can predict CRF more accurately than the ACSM.


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