Spontaneous Cerebrospinal Fluid Otorrhea in Association with a Congenital Defect of the Cochlear Aqueduct and Mondini Dysplasia

Neurosurgery ◽  
1982 ◽  
Vol 11 (3) ◽  
pp. 356-362 ◽  
Author(s):  
Tae Sung Park ◽  
Harold J. Hoffman ◽  
Robin P. Humphreys ◽  
Sylvester H. Chuang
Keyword(s):  
Congenital Anomaly ◽  
Cerebrospinal Fluid ◽  
Bacterial Meningitis ◽  
The Other ◽  
Csf Leak ◽  
Cystic Dilatation ◽  
Cochlear Aqueduct ◽  
Mondini Dysplasia ◽  
Cerebrospinal Fluid Otorrhea ◽  
Suboccipital Approach

Abstract Unrecognized spontaneous cerebrospinal fluid (CSF) otorrhea led to recurrent bacterial meningitis in three children. The underlying cause of the spontaneous CSF otorrhea was proved to be a congenital cystic dilatation of the cochlear aqueduct and Mondini dysplasia of the temporal bone. The CSF leak recurred in all patients after an initial surgical attempt to close the defects through a tympanotomy. A suboccipital approach was used successfully to obliterate the CSF fistulas in two children; a translabyrinthine approach was used in the other. A search of the literature revealed that Mondini dysplasia is a congenital anomaly that can commonly cause spontaneous CSF otorrhea in children. The authors discuss the management of this uncommon entity on the basis of a literature review and their own experience.

scholarly journals Recurrent Bacterial Meningitis in a Child with Mondini Dysplasia

2014 ◽  
Vol 2014 ◽  
pp. 1-3
Author(s):  
Eda Kepenekli-Kadayifci ◽  
Ayşe Karaaslan ◽  
Serkan Atıcı ◽  
Adem Binnetoğlu ◽  
Murat Sarı ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Hearing Loss ◽  
Bacterial Meningitis ◽  
Complete Resolution ◽  
Signs And Symptoms ◽  
Accurate Diagnosis ◽  
Developmental Abnormality ◽  
Mondini Dysplasia ◽  
Csf Leakage ◽  
Underlying Pathology

Mondini dysplasia, also known as Mondini malformation, is a developmental abnormality of the inner and middle ears that can cause hearing loss, cerebrospinal fluid (CSF) leakage, and recurrent bacterial meningitis (RBM), which is defined as two or more episodes of meningitis separated by a period of convalescence and the complete resolution of all signs and symptoms. An accurate diagnosis of the underlying pathology is crucial to prevent further episodes from occurring. Herein, we present a three-year-old boy with RBM and unilateral sensorineural hearing loss. During the evaluation to determine the etiology of the RBM, cystic malformation in the cochlea and vestibular dilatation consistent with Mondini dysplasia were detected via computerized tomography (CT) of the temporal bone.

Cerebrospinal fluid otorrhea and pseudomonal meningitis in a child with Mondini dysplasia: case report

2015 ◽  
Vol 31 (9) ◽  
pp. 1613-1616 ◽  
Author(s):  
R. Nick Hernandez ◽  
Abhinav R. Changa ◽  
Luigi Bassani ◽  
Robert W. Jyung ◽  
James K. Liu
Keyword(s):  
Cerebrospinal Fluid ◽  
Case Report ◽  
Mondini Dysplasia ◽  
Cerebrospinal Fluid Otorrhea

scholarly journals Cerebrospinal fluid otorrhea secondary to non-otogenic meningitis in a child with Mondini dysplasia

2017 ◽  
Vol 2 ◽  
pp. 16-18
Author(s):  
Mariah E. Small ◽  
Matthew D. Cox ◽  
Adam B. Johnson ◽  
John L. Dornhoffer
Keyword(s):  
Cerebrospinal Fluid ◽  
Mondini Dysplasia ◽  
Cerebrospinal Fluid Otorrhea

scholarly journals A Case of Petrous Apex Meningocele: Unusual Presentation of Cerebrospinal Fluid Leak Following Adenoidectomy

2020 ◽  
Vol 27 (2) ◽  
pp. 135-139
Author(s):  
Byung Kil Kim ◽  
Yujin Heo ◽  
Doo-Sik Kong ◽  
Sang Duk Hong
Keyword(s):  
Cerebrospinal Fluid ◽  
Bacterial Meningitis ◽  
Cerebrospinal Fluid Leak ◽  
Csf Leak ◽  
Petrous Apex ◽  
Diagnostic Process ◽  
Recurrent Meningitis ◽  
Csf Rhinorrhea ◽  
Leakage Site ◽  
Fluid Leak

Cerebrospinal fluid (CSF) leak is possible and can be a cause of recurrent bacterial meningitis. Petrous apex meningocele (PAM) is mostly asymptomatic and is often found during incidental imaging tests. We experienced a case of CSF rhinorrhea with recurrent meningitis in bilateral PAM after adenoidectomy. This report highlights the diagnostic process of CSF leak, identification of leakage site, and surgical approach to petrous apex lesions.

Mondini Dysplasia: Spontaneous Cerebrospinal Fluid Otorrhea

1990 ◽  
Vol 16 (4-5) ◽  
pp. 260-264 ◽  
Author(s):  
James T. Wilson ◽  
Sander W. Leivy ◽  
Robert A. Sofferman ◽  
Steven L. Wald
Keyword(s):  
Cerebrospinal Fluid ◽  
Mondini Dysplasia ◽  
Cerebrospinal Fluid Otorrhea

scholarly journals Quantification of cerebrospinal fluid ferritin as a biomarker for CNS malignant infiltration

2008 ◽  
Vol 66 (3b) ◽  
pp. 720-724 ◽  
Author(s):  
Sérgio Monteiro de Almeida ◽  
Dione Sosnitzki da Cunha ◽  
Edna Yamada ◽  
Elvira Missako Doi ◽  
Margaret Ono
Keyword(s):  
Cerebrospinal Fluid ◽  
Bacterial Meningitis ◽  
Enzyme Immunoassay ◽  
Neurological Diseases ◽  
Ferritin Level ◽  
The Other ◽  
Acute Bacterial Meningitis ◽  
Malignant Cells

Several markers have been studied for their ability to make the CNS infiltration diagnosis earlier and more precise; previous studies showed that CSF ferritin concentrations were higher in patients with malignant invasion of CNS. The objective was to determine the importance of CSF ferritin as a biomarker for the diagnosis of CNS neoplasic infiltration. This study is based on 93 CSF samples, divided into five groups: malignant cells present (n13); malignant cells not present (n26); inflammatory neurological diseases (n16); neurocysticercosis (n20); acute bacterial meningitis (n18). CSF ferritin values were determined by micro particle enzyme immunoassay. CSF ferritin level (mean±SD) in the group with neoplasic cells in the CSF was 42.8±49.7 ng /mL, higher than in the other groups (p<0.0001). We conclude that CSF ferritin with the cut off 20 ng/mL could be an adjuvant biomarker to the diagnosis of CNS malignant infiltration.

scholarly journals Invasive meningococcal disease at a military base in Warsaw, January 2007

2007 ◽  
Vol 12 (9) ◽  
Author(s):  
M Kadlubowski ◽  
I Wasko ◽  
A Klarowicz ◽  
W Hryniewicz
Keyword(s):  
Cerebrospinal Fluid ◽  
Intensive Care ◽  
Bacterial Meningitis ◽  
Neisseria Meningitidis ◽  
Intensive Care Units ◽  
Meningococcal Disease ◽  
The Other ◽  
Military Base ◽  
National Reference ◽  
Reference Centre

On 5 January 2007, two soldiers from a military base in Warsaw, Poland, presented with symptoms indicating fulminant sepsis. The soldiers were admitted to intensive care units in two different hospitals. Neisseria meningitidis was isolated from blood and cerebrospinal fluid in the case of one patient and from blood only in the case of the other, and sent to the National Reference Centre for Bacterial Meningitis (NRCBM) for further characterisation.

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