scholarly journals True hermaphroditism in chimaeric mice

Development ◽  
1964 ◽  
Vol 12 (4) ◽  
pp. 735-757
Author(s):  
Andrzej K. Tarkowski
Keyword(s):  
Special Reference ◽  
Reproductive System ◽  
Sex Chromosome ◽  
A Priori ◽  
Microscopic Structure ◽  
Chromosome Mosaicism ◽  
Preliminary Communication ◽  
Number Of Individuals ◽  
Macroscopic Examination ◽  
Newborn Animals

In a preliminary communication on the development of mouse chimaerae formed from fused eggs (Tarkowski, 1961) three cases of intersexuality were reported among newborn animals. Sexing was based exclusively on macroscopic examination of the reproductive system. The present paper deals with the microscopic structure of this system in chimaeric hermaphrodites, with special reference to the structure of the gonads. The occurrence of intersexes among animals developed from fused eggs was considered as one of the proofs of their chimaeric constitution (Tarkowski, 1961). Abnormalities similar to those displayed by these chimaerae have been described in the mouse and related rodents in sporadic spontaneous cases of hermaphroditism. However, while the genesis of the latter is unknown, there are strong indications that hermaphroditism among chimaerae develops on the basis of sex-chromosome mosaicism. This type of mosaicism can be expected a priori to occur in a number of individuals developed from two eggs randomly selected.

Fluorescence In Situ Hybridization Analysis of Sex-Chromosome Mosaicism in Azoospermic Men

2001 ◽  
Vol 22 (6) ◽  
pp. 970-972 ◽  
Author(s):  
HIROSHI OKADA ◽  
MASAKI DOBASHI ◽  
TAKAFUMI YAMAZAKI ◽  
MASATO FUJISAWA ◽  
SOICHI ARAKAWA ◽  
...  
Keyword(s):  
In Situ Hybridization ◽  
Fluorescence In Situ Hybridization ◽  
Sex Chromosome ◽  
Hybridization Analysis ◽  
Chromosome Mosaicism

Sex-Chromosome Mosaicism of Type XYY/XO

1962 ◽  
Vol 266 (14) ◽  
pp. 699-702 ◽  
Author(s):  
Herbert L. Cooper ◽  
Herbert S. Kupperman ◽  
Orlando R. Rendon ◽  
Kurt Hirschhorn
Keyword(s):  
Sex Chromosome ◽  
Chromosome Mosaicism

scholarly journals STUDY OF CLINICOPATHOLOGICAL SPECTRUM OF OVARIAN NEOPLASMS WITH SPECIAL REFERENCE TO EXPRESSION OF ER AND PR IN MALIGNANT LESIONS

2020 ◽  
pp. 67-69
Author(s):  
Sujata Ganguli ◽  
Keya Basu ◽  
Ranjana Bandyopadhyay
Keyword(s):  
Germ Cell ◽  
Special Reference ◽  
Reproductive System ◽  
Ovarian Neoplasms ◽  
Germ Cell Tumours ◽  
Female Reproductive System ◽  
Gynaecological Malignancy ◽  
Ovarian Tumours ◽  
Epithelial Tumours ◽  
Malignant Lesions

Ovarian carcinoma is the second most common carcinoma of the female reproductive system .It is the leading cause of death from gynaecological malignancy .The purpose of this study is to observe the clinicopathological spectrum of ovarian neoplasms with the expression of ER and PR in the different malignant lesions .A total of 156 cases of ovarian tumours were included in this study, and surface epithelial tumours were found to be the commonest neoplasm followed by germ cell tumours. Expression of ER and PR was found to be highest in Serous and Endometrioid tumours. PR Negative cases showed a higher grade and stage.

Increased frequency of heterozygotes for α1 antitrypsin variants in individuals with either sex chromosome mosaicism or trisomy 21

Nature ◽  
1976 ◽  
Vol 260 (5549) ◽  
pp. 320-321 ◽  
Author(s):  
ROBERT M. FINEMAN ◽  
KENNETH K. KIDD ◽  
A. MYRON JOHNSON ◽  
W. ROY BREG
Keyword(s):  
Trisomy 21 ◽  
Sex Chromosome ◽  
Chromosome Mosaicism

scholarly journals The histology of the cell wall, with special reference to the mode of connexion of cells. preliminary communication

1898 ◽  
Vol 62 (379-387) ◽  
pp. 100-112 ◽  
Keyword(s):  
Cell Wall ◽  
Cell Membrane ◽  
Special Reference ◽  
Original Method ◽  
New Method ◽  
Endosperm Tissue ◽  
Preliminary Communication

Since 1883 I have repeatedly endeavoured to discover some refined and generally applicable method by means of which the fine fibrillæ, or “connecting threads,” traversing the cell membrane might be identified with certainty, and the fact of their existence settled beyond dispute. I was also anxious to be in a position to investigate the development of the threads in endosperm tissue. My researches met with little encouragement until 1894, when I succeeded in finding a new method, by means of which I obtained excellent results with the young developing endosperm tissue of Tamus communis . This I have further elaborated, so that either the original method, or modifications of it, can be applied to tissues generally.

scholarly journals Further observations on the Diagnosis of Ankylostoma Infection with Special reference to the Examination of the Blood

1904 ◽  
Vol 4 (4) ◽  
pp. 437-479 ◽  
Author(s):  
A. E. Boycott
Keyword(s):  
Special Reference ◽  
Large Body ◽  
Final Diagnosis ◽  
Medical Examination ◽  
Coal Field ◽  
Number Of Individuals

The experience of the last few years in the Westphalian coal-field has shewn that the presence of Ankylostoma in a mine may become a matter of considerable industrial importance. Since it has been shewn that several of the metalliferous mines in Cornwall are throughly infected, the question of how far it may be present in, or spread to, other British mines has arisen in a practical form. When any large number of individuals have to undergo a medical examination for any such purpose it is of importance that such examination should be convenient at once for the examiner and for the examinee, that it should occupy as short a time as possible, and should, at the same time, be reliable. The diagnosis of the presence of Ankylostoma is commonly made by searching for the characteristic eggs in the faeces; and indeed a final diagnosis must rest in nearly every case on the results of this procedure. Which is therefore not easily replaced by any other method when separate individuals are in question. But as applied to a large body of active working men this process has many disadvantages, and at the request of the Home Secretary an inquiry has been made into the practicability of other methods of examination1.

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