Late Failure of a Polyethylene Unicompartmental Knee Insert -Retrieval Analysis Protocol and Results

This study reports the investigation of a degraded polyethylene insert retrieved after the catastrophic failure of a mobile bearing knee implant, occurred after a traumatic event and leading to a late revision. Understanding wear mechanisms of polyethylene components is important to improve the implants for joint replacement. This model of unicompartmental arthroplasty, due to its mobile, congruent insert and design, has the potential to attain low rates of wear, leading to an improved survival of the prosthesis over fixed-bearing knee implants. During the surgical technique, however, it is critical to avoid any source of impingement or incongruent articulation, as this are associated with increased rates of polyethylene wear and may contribute to the early necessity for revision surgery. The investigated insert presented a macroscopic fragmentation, surface and bulk defects and debris. Characterization of the retrieved polyethylene implant fragments was performed by macroscopic examination, by scanning electron microscopy and Fourier transform infrared spectroscopy. Due to a systematic retrieval analysis according to current standards, we can question that, in our case, third body wear is rarely pure bone or pure cement debris related but a combination of the two mentioned. The combination enhanced contribution of polyethylene debris in severe wear initiation and progression. Complete examination of the explants exhibiting breakage or severe wear may help in understanding pathogenic ways of failure in unicompartmental knee.

Pathomorphological changes in the early postnatal period in a calf with abomasum rupture

The main cause of the disease and death of calves in the early postembryonic period of development is a feeding disorder. The aim of the work was to analyze macro-and micromorphological changes in the digestive system of a calf with a rennet rupture. To achieve this goal, standard macro-and microscopic research methods were used. Macroscopic examination revealed thickening, erosion of the mucous membrane of the esophageal gutter rollers, accumulation of contents in the scar, mesh and book, hyperemia of the mucous membranes; thinning and rupture of the rennet wall; pronounced hyperemia of the mucous membrane of the small intestine, thickening of the mucous membrane of the thick section; an increase in mesenteric lymph nodes and a change in their consistency. Microscopically, the thickness of the epithelium, submucosal and muscle layer is most developed in the abomasum and was, respectively, 0.68-0.72 mm, 0.23-0.32 mm and 0.98-1.05 mm. Villi were found in the folds of the scar, numerous well – developed longitudinally oriented protrusions were found in the book, lymphocellular clusters and bottom glands were found in the rennet; folds with well – developed crypts were found in the colon. Thus, as a result of feeding coarse feed, the deceased calf has catarrhal erosive lesions of the esophageal trough; serous-catarrhal abomasitis with signs of hemorrhagic with dilation and perforation in the cardiac part; hemorrhagic omasitis against the background of a book blockage; catarrhal reticulitis; catarrhal ruminitis and catarrhal enterocolitis.

An Autopsy Report of Hypoplastic Coronary Artery Disease Incidentally Identified in a Young Man

Hypoplastic coronary artery disease (HCAD) is a rare congenital abnormality characterized by underdevelopment of one or more major branches of the coronary arteries, which may lead to myocardial infarction and sudden death. We report a case of HCAD that was incidentally detected during autopsy in a 25-year-old male soldier who died during underwater escape training. On macroscopic examination, the right coronary artery measured 1 mm in diameter, which was significantly smaller than that of other coronary arteries. We observed no anomalies in addition to HCAD. Death was attributed to drowning, which was consistent with autopsy findings and the circumstances of death. Although extremely rare, if sudden cardiac death is suspected in children and young adults, it must be confirmed through careful evaluation.

Autopsy findings of suicidal hanging in Mugla, Turkey

Introduction: External and internal autopsy findings of suicidal hanging were evaluated retrospectively in Muğla, Turkey. The relations between macroscopic autopsy findings and age, gender, nature of the ligature, position of the knot, and the ligature marks were assessed. The aim of this study was to describe autopsy findings of the hangings and discuss the regional differences. Method: The reports of 175 hanging autopsies between 2013 to 2018 were evaluated retrospectively. Macroscopic external and internal findings were evaluated and compared statistically. Results: Among the 2534 autopsies, the cause of death was suicide by hanging in 175 cases (6.9%). The male-to-female ratio was 3:1, 76%(n = 133) of the cases were male, 24% (n = 42) were female, the mean age was 44.9(SD = 19.3) years. Suicide by hanging was most prevalent in the 25–44 age group and among men. Complete hanging was more common than incomplete hanging, and softer materials were more commonly used in incomplete hangings. Females utilized soft materials more than males. Males used atypical hanging more than females. Bilateral hemorrhage in the neck muscles was more common with typical hanging. There was a significant relationship between tongue protrusion and hemorrhage at the clavicular head of sternocleidomastoid muscle. Conclusion: In this study, which includes a large series, some regional and gender differences were observed. Careful and detailed macroscopic examination was important to diagnose antemortem vitality findings.

Sarcoptes sp. Infection in Turtledoves (Geopelia striata) at Banyuwangi

This study aimed to explain the case of ectoparasite infection and the life cycle of parasites in turtledoves (Geopelia striata). Sarcoptes sp. one of the ectoparasites belonging to the phylum Arthropods, the Arachnid class, and the order Acarina.Sarcoptes sp. can infect the skin of the host through direct contact with infected animals and the environment. Sarcoptes sp. infects by forming a lump under the skin and severe infection causes a crust to form on the skin and is accompanied by itching. Physical examination was carried out by means of inspection of the infected skin area. Subsequent examinations were carried out on the dead skin cells mixed with fresh manure macroscopically and microscopically. Macroscopic examination was done by observing the condition of the skin that is discraped. Microscopic examination using native examination. Based on the negative examination, it was found that there were Sarcoptes sp. mites on an objective microscope with a 40x magnification. Geopelia striata can be infected with Sarcoptes sp. through direct contact with sick animals. The incubation period of Sarcoptes sp. after infection from infected animals was 3-6 weeks.

Problems of primary fallopian tube cancer diagnostics during and after surgery

To date, the reliable diagnoses primary fallopian tube cancer (PFTC) before surgery range from 0% to 10–15%. Number of misdiagnosis even during operations reaches 30–50% and PFTC is often disguised as innocent hydro-hematosalpinx or other diseases.Research objective: to study the possibilities of PFTC diagnosis during laparotomy and laparoscopy, macroscopic examination of removed macrodrugs, suboperative use of morphological studies, problems of histological interpretation of PFTC after surgery.Materials and methods. During the period from 1966 to 2020 authors of article selected and retrospectively studied quite informative medical histories of 105 patients with PFTC aged 34 to 78 years (mean age 55.8 years). All patients were operated. Revision of the pelvic organs and abdominal cavity was performed during operations. Removed macrodrugs were examined macroscopically and histologically. According to the indications during operations histological and cytological methods of rapid diagnosis were used. Immunohistochemical methods were used to interpret rare and difficult to diagnose tumors after surgery.Results. Only 7 (6.6%) from 105 patients with PFTC was not recognized during surgery, and 18 (17.1%) were diagnosed only after suboperative histological examination. Errors during operations in the initial PFTC forms (without careful study of macrodrugs and suboperative morphological examination) can reach 23.8%. Problems with the primary lession interpretation, which arose in 11 (10.5%) patients with a pronounced tumor process, did not prevent the choice of adequate surgery. The tumor dissemination of the fallopian tube outside was detected in 69 (72.4%) patients, in 25 (26.2%) among them there were lymph node metastases.Conclusion. Careful revision of the abdominal organs and macroscopic examination of removed drugs using suboperative morphological studies avoids errors in the diagnosis and surgical treatment of patients with PFTC.

Investigation of Lesions In Goat Brain Collected From Abattoirs in Rajshahi Metropolitan Area

Brain lesions are important cause of morbidity and reduced productivity in goats worldwide. Works on brain lesion in goats are extremely rare in Bangladesh and remain to be investigated. We investigated lesions in goat brains collected from abattoirs in Rajshahi Metropolitan area by gross and microscopic examination. Randomly selected 57 goat brains were investigated of which 24.56% brains showed gross and histopathologic lesions. Prevalence of brain lesions were higher in Jamnapari goats (29.41%) compared to in Black Bengal goats (22.50%) and female goats (26.47%) were more affected than male goats (21.74%). Age-wise prevalence were 31.25%, 21.43%, 12.50%, and 40.00% in the age of up to 2 years, 2-3 years, 3-4 years, and above 4 years old goats, respectively. Goats were more affected in the rainy (35.29%) season in contrast to in the winter (23.53%) and in the summer (10.52%) seasons. The brains collected from goats with Gid disease showed uni or multilocular cysts containing clear fluid and multiple scolices, the rest of the brains were apparently healthy by macroscopic examination. Histopathologically, pyogranuloma, perivascular cuffing, gliosis, neuronal degeneration, hemorrhages, congestion and thrombus were evident. J. Bio-Sci. 29(1): 49-58, 2021 (June)

Reproductive Biology of the Tigris Scraper, Capoeta Umbla (Heckel, 1843) Population Living in Solhan Creek of Murat River (Bingöl, Turkey)

We studied the reproductive traits in 23 of 190 individuals of Capoeta umbla caught monthly in the Solhan Creek of the Murat River between April 2017 and March 2018. The sex ratio (F:M) was found to be 1:1.11. The macroscopic examination of the gonads and gonado-somatic index indicated that the reproductive period lasted from May to August with peak activity in May. The fecundity ranged from 2,000 to 9,000 oocytes, and it correlated with the total length and body weight. This work represents the first attempt to investigate the reproductive traits of the Capoeta umbla population in the Solhan Creek. The results provide information on the reproductive biology and contribute to the conservation of the fish population and its sustainable management.

Identifying Handsaw Tooth Shape Based on the Micro- and Macroscopic Analysis of the Kerf Floor Contour

Skeletal trauma analysis is a major facet of forensic anthropology casework and can entail interpretation of sharp force saw trauma. Hand-powered saws are commonly used in cases of dismemberment and analysis requires differentiating class characteristics. Features of the kerf walls and floor provide information utilized in identifying set, shape, size, power, and direction of sawing motion of the tool. The focus of this study is to examine validity and reliability of determining tooth shape class characteristic (rip versus crosscut) from features of the kerf floor. Two crosscut and three rip handsaws, ranging from 6 to 16 teeth per inch, were used to make 30 incomplete cuts per saw for a total of 150 cuts. Each kerf floor was analyzed macroscopically and microscopically using a digital microscope at 30 × magnification by three observers of different experience levels (expert, experienced, and novice). Profile shapes were classified as U-shaped/concave (rip) or W-shaped/convex (crosscut) by each observer for all 150 cuts. Reliability tests using Cohen’s kappa ranged from substantial in the two less experienced observers to almost perfect in pairwise comparisons with the expert. Microscopic classification accuracy was 94.0% (423/450) for all three observers and macroscopic examination increased accuracy to 99.8% (449/450). Saw wear and tooth size were not a significant determiner in correct identification of saw tooth type. Overall, tooth shape can be reliably and accurately determined from incomplete cuts.